CuSTOM Solutions: Revolutionizing Organ Disease Care with Stem Cell and Organoid Innovations
Cincinnati Children’s Center for Stem Cell and Organoid Medicine (CuSTOM), established in 2017, comprises 37 research laboratories where investigators collaborate with clinical teams, industry partners and other research institutions worldwide with the goal of transforming the care of end-stage organ disease.
CuSTOM’s flagship technologies utilize novel approaches using human pluripotent stem cells (hPSCs), which can be made into bioengineered organoids. Although miniature in size, organoids function like the patient’s own organ. They possess complex tissue structures, multiple cell types, and perform organ functions.
With generous philanthropic support from the Farmer Family Foundation, Cincinnati Children’s established the CuSTOM Accelerator Lab, a state-of-the-art facility with advanced robotics for high-throughput manufacturing and analysis of human organoids from patient stem cells. The CuSTOM Accelerator Lab is dedicated to translating groundbreaking discoveries into next-generation therapeutics and regenerative medicine to revolutionize child health.
Read more about Organoid Research on our Research Horizons Science Blog
Listen to the Science Podcast on gastrointestinal organoids.
Meet the CuSTOM Organoids Team.
