Weight Loss Surgery on Lipid Subspecies Composition and Function

Severe obesity is a growing problem among adolescents. Unfortunately, few effective therapies exist for weight loss. Bariatric weight loss surgery is growing in popularity because it results in dramatic weight loss and improves metabolic diseases. Our lab aims to understand how weight loss surgeries alter lipid subspecies composition and function and how this surgery may improve cardiovascular disease risk.

Funding

This work has been funded through an Early Career Development Award from The Central Society for Clinical and Translational Research; a research grant from the Pediatric Diabetes and Obesity Center, and in part by Cincinnati Children’s Hospital Medical Center.

Publications from this Study

Shah, AS; Jenkins, T; Gao, Z; Daniels, SR; Urbina, EM; Kirk, S; Siegel, R; Inge, TH. Lipid Changes 8 Years Post Gastric Bypass in Adolescents with Severe Obesity (FABS-5+ Study). Int J Obes. 2017 Oct;41(10):1579-1584.

Davidson, WS; Inge, TH; Sexmith, H; Heink, A; Elder, D; Hui, DY; Melchior, JT; Kelesidis, T; Shah, AS. Weight loss surgery in adolescents corrects high density lipoprotein subspecies and their function. Int J Obesity. 2017 Jan;41(1):83-89.