Cohen KB, Glass B, Greiner HM, Holland-Bouley K, Standridge S, Arya R, Faist R, Morita D, Mangano F, Connolly B, Glauser T, Pestian J. Methodological Issues in Predicting Pediatric Epilepsy Surgery Candidates Through Natural Language Processing and Machine Learning. Biomed Inform Insights. 2016 May 22;8:11-8.
The study described the development of natural language processing and machine learning to review free text in an electronic medical record to identify potential epilepsy surgery candidates. This allowed inclusion of often overlooked patients, while also expediting the process of identification.
Cobb-Pitstick KM, Hershey AD, O'Brien HL, Kabbouche MA, LeCates S, White S, Vaughn P, Manning P, Segers A, Bush J, Horn PS, Kacperski J. Factors Influencing Migraine Recurrence After Infusion and Inpatient Migraine Treatment in Children and Adolescents. Headache. 2015 Nov-Dec;55(10):1397-403.
This manuscript addressed the recurrence of headaches after acute infusion treatment or inpatient treatment of pediatric and adolescent migraine, allowing for prediction of who would be more likely to require additional treatment options.
Kroner JW, Hershey AD, Kashikar-Zuck SM, LeCates SL, Allen JR, Slater SK, Kabbouche MA, O'Brien HL, Shenk CE, Rausch JR, Kroon Van Diest AM, Powers SW. Cognitive Behavioral Therapy plus Amitriptyline for Children and Adolescents with Chronic Migraine Reduces Headache Days to four Per Month. Headache. 2016 Apr;56(4):711-6.
This study examined the efficacy of cognitive behavioral therapy in children and adolescents, finding that cognitive behavioral study was more effective than educational controls in reducing headache frequency to one a week or less.
Oldham MS, Horn PS, Tsevat J, Standridge S. Costs and Clinical Outcomes of Epilepsy Surgery in Children With Drug-Resistant Epilepsy. Pediatr Neurol. 2015 Sep;53(3):216-20.
This study examined both the outcomes and cost of epilepsy surgery in the pediatric population, identifying that if surgery freedom is achieved, the overall cost is reduced. This manuscript also received a resident award from the Child Neurology Society.
Pedapati EV, Gilbert DL, Erickson CA, Horn PS, Shaffer RC, Wink LK, Laue CS, Wu SW. Abnormal Cortical Plasticity in Youth with Autism Spectrum Disorder: A Transcranial Magnetic Stimulation Case-Control Pilot Study. J Child Adolesc Psychopharmacol. 2016 Sep;26(7):625-31.
This study demonstrated early evidence for a potential physiological biomarker of cortical plasticity in youth with ASD using a rapid low-intensity rTMS protocol with a discriminate measure at 20 minutes following stimulation. It builds on the growing evidence of rTMS in the understanding and treatment of neurological conditions in children.