Cincinnati Center for Eosinophilic Disorders Research
Clinical Trials

Clinical Studies and Trials for Eosinophilic Disorders

We are actively conducting research to help understand and improve outcomes for patients with eosinophilic disorders. For more information on our ongoing clinical research, open the descriptions of our clinical studies and trials below.

For research inquiries, contact the Cincinnati Center for Eosinophilic Disorders (CCED) at ccedresearch@cchmc.org.

For more of our clinical trials, visit these clinicaltrials.gov webpages:

Ongoing Clinical Studies & Trials

CEGIR OMEGA Study for Patients with Eosinophilic Esophagitis (EoE), Eosinophilic Gastritis (EoG), and Eosinophilic Colitis (EoC)

What is the purpose of this study?

The purpose of this observational research study is to find the best measures to define how well a person with eosinophilic disorder is doing. People with EoE, EoG, and EoC normally undergo endoscopy and/or colonoscopy where cells are collected for microscopic analysis. Treatments are then decided based on how the cells look.  We want to see if scores on standard questionnaires can give us an idea how well the person is doing.

Who can participate?

Children and adults ages 3-65 years that have been diagnosed with EoE, EoG, or EoC.

Details

General CEGIR OMEGA Description (PDF)
Adult (18-65 years) CEGIR OMEGA (PDF)
Pediatric (3-17 years) CEGIR OMEGA (PDF)

Who should I contact for more information?

ccedresearch@cchmc.org

Where can I find additional information?

https://www.rarediseasesnetwork.org/cms/CEGIR

CEGIR OMEGA Protocol Version 4.0

Eosinophilic Gastrointestinal Disorders 

Have you or your child been diagnosed with an Eosinophilic Gastrointestinal Disorder (EGID)?  The Cincinnati Center for Eosinophilic Disorders is conducting a research study designed to develop a better understanding and improved treatment plans for patients with an eosinophilic gastrointestinal disorders (EGID).

Who

Those of any age who have been diagnosed with an EGID.

What

Saliva samples and a brief medical history.

How

All study procedures will be done by phone, via mail and via the internet.

Why

To improve the understanding of the genetic factors of EGID.

Contact

If you are interested in participating or have any questions, please contact ccedresearch@cchmc.org

Family Tree Study

Have several people in your family been diagnosed with an Eosinophilic Gastrointestinal Disorder (EGID)? The Cincinnati Center for Eosinophilic Disorders is conducting a research study designed to develop a better understanding and improved treatment plans for patients with eosinophilic gastrointestinal disorders (EGID).

Who

Families who have more than one member diagnosed with an EGID, particularly those families with three generations of diagnoses (e.g. grandparent, parent, and child), or families with cousins who have been diagnosed. 

What

Saliva samples and a brief medical history will be collected. 

How

All study procedures will be done by phone, via mail, and via the internet.

Why

To better understand genetic factors that may influence how EGID is passed down through families.

Contact

If you are interested in participating or have any questions, please contact ccedresearch@cchmc.org

Twin Study  

Are you a twin diagnosed with an Eosinophilic Gastrointestinal Disorder (EGID)?   The Cincinnati Center for Eosinophilic Disorders is conducting a research study designed to develop a better understanding and improved treatment plans for patients with eosinophilic gastrointestinal disorders (EGID). 

Who

Identical and fraternal twins and multiple births of all ages with at least one sibling diagnosed with an EGID.

What

Saliva samples and a brief medical history will be collected.

How

All study procedures will be done by phone, via mail, and via the internet.

Why

To identify the genetic and environmental factors that contribute to the diagnosis of an EGID. 

Contact

If you are interested in participating or have any questions, please contact ccedresearch@cchmc.org

CEGIR

The Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) is dedicated to improving the lives of individuals with eosinophilic gastrointestinal disorders through innovative research, clinical expertise and education via collaborations between scientists, health care providers, patients, and professional organizations. CEGIR is part of the Rare Diseases Clinical Research Network (RDCRN) and has a contact registry. Consider joining today.

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Mother with son.
Our clinical trials are not only for children. See the Ongoing Clinical Trials descriptions on this page for specifics of who are eligible to participate.
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