Cincinnati Center for Eosinophilic Disorders Research
Associated Labs

Labs and Divisions Associated with the CCED

The Cincinnati Center for Eosinophilic Disorders (CCED) works closely with many labs and divisions throughout Cincinnati Children’s and the University of Cincinnati: 

Labs

Rothenberg CURED Lab

The Rothenberg CURED Research Lab is focused on elucidating the mechanisms of allergic responses, especially in mucosal tissues such as the gastrointestinal tract and lung. 

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Shoda Lab

The Shoda Lab is working to identify the key genes and genetic regulatory mechanisms that predispose patients to eosinophilic conditions, especially eosinophilic gastrointestinal diseases (EGID). 

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Azouz Lab

The Azouz Lab investigates the function and regulation of proteases in host defense and in the onset and propagation of inflammatory and allergic diseases. 

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Kottyan Lab

The Kottyan Lab is focused on identifying the molecular mechanisms that underlie specific genetic associations with human disease.

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Weirauch Lab

The Weirauch Lab is working to understand the mechanisms of gene transcriptional regulation, using computational methods to study how, when, where, and why genes are “turned on and off”.

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Divisions

Allergy and Immunology

The Division of Allergy and Immunology at Cincinnati Children’s conducts leading research focused on elucidating the causes, mechanisms and most effective treatment of allergic and immunological diseases. Our research spans fundamental studies, translational investigations, genetic and genomic analyses, computational science, and clinical trials to enhance our understanding of immunity with a focus on mast cells, eosinophils, macrophages, lymphocytes, epithelium and stem cells.

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Behavioral Medicine and Clinical Psychology

Research within the Division of Behavioral Medicine and Clinical Psychology (BMCP) focuses on improving long-term outcomes for patients by revealing the interactions among behavior, biology, family environment, community and child health. Our research faculty seek to translate our research into care practices and techniques that will directly impact the health and well being of today’s children.

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Biomedical Informatics

The Division of Biomedical Informatics (BMI) at Cincinnati Children's Research Foundation is committed to improving pediatric and adult health outcomes through the innovative application of biomedical data and informatics. Our researchers, staff and students use computational methods to solve pressing health problems in bioinformatics, clinical informatics and genomics. Our research advances the understanding of comparative/functional genomics, systems biology, and proteomics; natural language processing; genome-wide association studies of diseases; data warehousing and data mining; and high-performance computing.

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Gastroenterology, Hepatology and Nutrition

The Division of Gastroenterology, Hepatology and Nutrition at Cincinnati Children’s specializes in treatment and research for gastrointestinal, liver and nutritional disorders. Faculty of the Division of Gastroenterology, Hepatology and Nutrition and the Division of Allergy and Immunology frequently collaborate in areas of research including eosinophilic gastrointestinal disorders and inflammatory bowel disease.

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Human Genetics

The Division of Human Genetics at Cincinnati Children's specializes in treatment and research of heritable disorders and has the overall research goal of creating unified platforms for complex phenotyping, genomic dissection and translation of personalized approaches to medical care and enhanced outcomes for individuals afflicted with gene-influenced diseases.

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Pathology

The Division of Pathology has active research programs at the clinical and basic science level. Ongoing clinical collaborative studies involve most clinical subdivisions at Cincinnati Children’s including a wide range of clinical disorders such as eosinophilic GI disorders, motility disorders, metabolic liver diseases, inflammatory bowel disease, interstitial lung disease and muscle disorders.

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