Pulmonary Biology
Meet the Team

Meet our Experts

Co-Directors

A photo of Jichao Chen.

Jichao Chen, PhD, MHS

Professor, UC Department of Pediatrics

Email jichao.chen@cchmc.org

Research Interests

lung development; single-cell genomics; mouse genetics; 3D imaging; artificial intelligence

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Faculty

A photo of Paritha Arumugam.

Paritha I. Arumugam, PhD

Assistant Professor, UC Department of Pediatrics

Email paritha.arumugam@cchmc.org

Research Interests

Gene therapy for inherited disorders; Hereditary Pulmonary Alveolar Proteinosis (hPAP)

Brenna C. Carey, MS, PhD

Assistant Professor, UC Department of Pediatrics

Email brenna.carey@cchmc.org

Research Interests

Regulations, management, and coordination of clinical research trials in rare lung diseases, specifically pulmonary alveolar proteinosis (PAP);...

A photo of Hitesh Deshmukh.

Hitesh S. Deshmukh, MD, PhD

Associate Professor, UC Department of Pediatrics

Email hitesh.deshmukh@cchmc.org

A photo of Mingxia Gu.

Mingxia Gu, MD, PhD

Assistant Professor, UC Department of Pediatrics

Email mingxia.gu@cchmc.org

Research Interests

Development of heart, lung, and vasculature; human induced pluripotent stem cells; organoid; high-throughput drug screening; human genetics Visit the...

Minzhe Guo.

Minzhe Guo, PhD

Assistant Professor, UC Department of Pediatrics

Email minzhe.guo@cchmc.org

Research Interests

Developing novel computational methods and software tools to support single cell multi-omics data analysis and integration for scientific discovery...

A photo of Timothy LeCras.

Timothy D. Le Cras, PhD

Professor, UC Department of Pediatrics

Email tim.lecras@cchmc.org

Research Interests

Pathogenesis of vascular anomalies; vascular malformations; kaposiform lymphangiomatosis; capillary lymphatic venous malformations; pulmonary...

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Yutaka Maeda, DVM, PhD

Assistant Professor, UC Department of Pediatrics

Email yutaka.maeda@cchmc.org

A photo of Yifei Miao.

Yifei Miao, MBBS, PhD

Assistant Professor, UC Department of Pediatrics

Email yifei.miao@cchmc.org

Research Interests

Organoids; human pluripotent stem cell; congenital cardiac and pulmonary defect; single ventricle defects; epigenetic regulation

Anne-Karina Theresia Perl, MS, PhD

Professor, UC Department of Pediatrics

Email anne.perl@cchmc.org

Research Interests

Lung development and regeneration; fibroblast function in development, regeneration and fibrosis

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A photo of Debora Sinner.

Debora I. Sinner, PhD

Assistant Professor, UC Department of Pediatrics

Email debora.sinner@cchmc.org

Research Interests

Developmental biology; lung development; congenital defects

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A photo of Bruce Trapnell.

Bruce C. Trapnell, MS, MD

Professor, UC Department of Pediatrics

Email bruce.trapnell@cchmc.org

Research Interests

Alveolar macrophage function; molecular techniques using gene knockout, transgenic and conditional gene expression mouse models and non-human...

Guolun Wang

Instructor, UC Department of Pediatrics

Email guolun.wang@cchmc.org

Research Interests

Chromatin regulation of cell specific transcription output

A photo of Kathryn Wikenheiser-Brokamp.

Kathryn A. Wikenheiser-Brokamp, MD, PhD

Professor, UC Department of Pathology and Laboratory Medicine

Email kathryn.wikenheiser-brokamp@cchmc.org

A photo of Yan Xu.

Yan Xu, PhD

Professor, UC Department of Pediatrics

Email yan.xu@cchmc.org

Research Interests

Yan Xu: main area of research interests are bioinformatics and systems biology application in pulmonary research. Our current focus is to...

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A photo of William Zacharias.

William J. Zacharias, MD, PhD

Assistant Professor, UC Department of Pediatrics

Email william.zacharias@cchmc.org