Publications

Pham, TD; Chng, MH Y; Roskin, KM; Jackson, KJ L; Nguyen, KD; Glanville, J; Lee, J; Engleman, EG; Boyd, SD. High-fat diet induces systemic B-cell repertoire changes associated with insulin resistance. Mucosal Immunology. 2017; 10:1468-1479.

Ellebedy, AH; Jackson, KJ L; Kissick, HT; Nakaya, HI; Davis, CW; Roskin, KM; McElroy, AK; Oshansky, CM; Elbein, R; Thomas, S; Mehta, AK; Thomas, PG; Boyd, SD; Ahmed, R. Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination. Nature Immunology. 2016; 17:1226-1234.

Hoh, RA; Joshi, SA; Liu, Y; Wang, C; Roskin, KM; Lee, J; Pham, T; Looney, TJ; Jackson, KJ L; Dixit, VP; Jenks, J; Hamilton, RG; Nadeau, KC; Boyd, SD. Single B-cell deconvolution of peanut-specific antibody responses in allergic patients. Journal of Allergy and Clinical Immunology. 2016; 137:157-167.

Collins, AM; Wang, Y; Roskin, KM; Marquis, CP; Jackson, KJ L. The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains. Philosophical Transactions of the Royal Society of London: Biological Sciences. 2015; 370.

Roskin, KM; Simchoni, N; Liu, Y; Lee, J; Seo, K; Hoh, RA; Pham, T; Park, JH; Furman, D; Dekker, CL; Davis, MM; James, JA; Nadeau, KC; Cunningham-Rundles, C; Boyd, SD. IgH sequences in common variable immune deficiency reveal altered B cell development and selection. Science Translational Medicine. 2015; 7:302ra135.

Wang, C; Liu, Y; Cavanagh, MM; Le Saux, S; Qi, Q; Roskin, KM; Looney, TJ; Lee, J; Dixit, V; Dekker, CL; Swan, GE; Goronzy, JJ; Boyd, SD. B-cell repertoire responses to varicella-zoster vaccination in human identical twins. Proceedings of the National Academy of Sciences of USA. 2015; 112:500-505.

Jackson, KJ L; Liu, Y; Roskin, KM; Glanville, J; Hoh, RA; Seo, K; Marshall, EL; Gurley, TC; Moody, MA; Haynes, BF; Koller, D; Davis, MM; Fire, AZ; Boyd, SD. Human responses to influenza vaccination show seroconversion signatures and convergent antibody rearrangements. Cell Host and Microbe. 2014; 16:105-114.

Wang, C; Liu, Y; Xu, LT; Jackson, KJ L; Roskin, KM; Pham, TD; Laserson, J; Marshall, EL; Seo, K; Lee, J; Dekker, CL; Davis, MM; Fire, AZ; Boyd, SD. Effects of aging, cytomegalovirus infection, and EBV infection on human B cell repertoires. Journal of immunology (Baltimore, Md. : 1950). 2014; 192:603-611.

Parameswaran, P; Liu, Y; Roskin, KM; Jackson, KK L; Dixit, VP; Lee, J; Artiles, KL; Zompi, S; Jose Vargas, M; Simen, BB; Balmaseda, A; Boyd, SD; Harris, E; Fire, AZ. Convergent antibody signatures in human dengue. Cell Host and Microbe. 2013; 13:691-700.

Liao, H; Lynch, R; Zhou, T; Gao, F; Alam, SM; Boyd, SD; Fire, AZ; Roskin, KM; Schramm, CA; Zhang, Z; Kwong, PD; Mascola, JR; Haynes, BF; Progra, NI S C C S. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature. 2013; 496:469-476.

DeVore, SB; Schuetz, M; Alvey, L; Lujan, H; Ochayon, DE; Williams, L; Chang, WC; Filuta, A; Ruff, B; Kothari, A; Keles, S; Milner, JD; Supp, DM; Khurana Hershey, GK. Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease. Cell Reports. 2024; 43:114589.

Tsuda, S; Shichino, S; Tilburgs, T; Shima, T; Morita, K; Yamaki-Ushijima, A; Roskin, K; Tomura, M; Sameshima, A; Saito, S; Nakashima, A. CD4+ T cell heterogeneity in gestational age and preeclampsia using single-cell RNA sequencing. Frontiers in Immunology. 2024; 15:1401738.

Garrett, MC; Albano, R; Carnwath, T; Elahi, L; Behrmann, CA; Pemberton, M; Woo, D; O’Brien, E; VanCauwenbergh, B; Perentesis, J; Roskin, K; Kornblum, H; Plas, DR; Lu, QR. HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma. Scientific Reports. 2023; 13:12433.

Dexheimer, PJ; Pujato, M; Roskin, KM; Weirauch, MT. VExD: a curated resource for human gene expression alterations following viral infection. G3-Genes Genomes Genetics. 2023; 13.

Shi, T; Burg, AR; Caldwell, JT; Roskin, KM; Castro-Rojas, CM; Chukwuma, PC; Gray, GI; Foote, SG; Alonso, JA; Cuda, CM; Shields, AR; Baker, BM; Woodle, ES; Hildeman, DA. Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality. The Journal of Clinical Investigation. 2023; 133.

Rossi, AP; Tremblay, S; Castro-Rojas, CM; Burg, AA; Roskin, KM; Gehman, JM; Rike-Shields, A; Alloway, RR; Brailey, P; Allman, D; Hildeman, DA; Woodle, ES. Effects of invivo CXCR4 blockade and proteasome inhibition on bone marrow plasma cells in HLA-sensitized kidney transplant candidates. American Journal of Transplantation. 2023; 23:759-775.

Gill, K; Moore, C; Nwogu, O; Kroner, JW; Chang, W; Stevens, ML; Kyzy, AB; Biagini, JM; Devonshire, AL; Kottyan, L; Martin, LJ; Andorf, S; Hershey, GK K; Roskin, KM. B cell repertoire in children with skin barrier dysfunction supports altered IgE maturation associated with allergic food sensitization. 2023.

Garrett, MC; Albano, R; Carnwath, T; Shah, S; Woo, D; Lamba, M; Plas, DR; Paranjpe, A; Roskin, K; Zhao, C; Lu, R. Chromatin structure predicts survival in glioma patients. Scientific Reports. 2022; 12:8221.

Williams, JG; Joshi, R; Haslam, D; Yehya, N; Jones, RL; Paranjpe, A; Pujato, M; Roskin, KM; Lahni, PM; Wong, HR; Varisco, BM. Multi-omic characterization of pediatric ARDS via nasal brushings. Respiratory Research. 2022; 23:181.

McDaniel, MM; Chawla, AS; Jain, A; Meibers, HE; Saha, I; Gao, Y; Jain, V; Roskin, K; Way, SS; Pasare, C. Effector memory CD4+ T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells. Science Immunology. 2022; 7:eabk0182.

Shi, T; Roskin, K; Baker, BM; Woodle, ES; Hildeman, D. Advanced Genomics-Based Approaches for Defining Allograft Rejection With Single Cell Resolution. Frontiers in Immunology. 2021; 12:750754.

Chen, JA; Hou, Y; Roskin, KM; Arber, DA; Bangs, CD; Baughn, LB; Cherry, AM; Ewalt, MD; Fire, AZ; Fresard, L; Pearce, KE; Pitel, BA; Merker, JD; Gotlib, J. Lymphoid blast transformation in an MPN with BCR-JAK2 treated with ruxolitinib: putative mechanisms of resistance. Blood Advances. 2021; 5:3492-3496.

Yang, F; Nielsen, SC A; Hoh, RA; Röltgen, K; Wirz, OF; Haraguchi, E; Jean, GH; Lee, JY; Pham, TD; Jackson, KJ L; Nadeau, KC; Niemann, CU; Parsonnet, J; Boyd, SD. Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues. Science. 2021; 372:738-741.

Wagar, LE; Salahudeen, A; Constantz, CM; Wendel, BS; Lyons, MM; Mallajosyula, V; Jatt, LP; Adamska, JZ; Blum, LK; Gupta, N; Robinson, WH; Boyd, SD; Kuo, CJ; Davis, MM. Modeling human adaptive immune responses with tonsil organoids. Nature Medicine. 2021; 27:125-135.

Varisco, B; Joshi, R; Jones, R; Paranjpe, A; Roskin, K; Yunger, T; Stoneman, E; Lahni, P; Wong, H; Williams, J. 1003: Nasal Transcriptomic and Serum Proteomic Identification of Three Pediatric ARDS Subtypes. Critical Care Medicine. 2021; 49:500.

Rai, MA; Hammonds, J; Pujato, M; Mayhew, C; Roskin, K; Spearman, P. Comparative analysis of human microglial models for studies of HIV replication and pathogenesis. Retrovirology. 2020; 17:35.

Woodle, ES; Tremblay, S; Rossi, A; Rojas, CC; Alloway, R; Roskin, K; Allman, D; Hildeman, D. Plasma cell targeting to prevent antibody-mediated rejection. American Journal of Transplantation. 2020; 20 Suppl 4:33-41.

Moore, C; Gao, B; Roskin, KM; Vasilescu, EM; Addonizio, L; Givertz, MM; Madsen, JC; Zorn, E. B cell clonal expansion within immune infiltrates in human cardiac allograft vasculopathy. American Journal of Transplantation. 2020; 20:1431-1438.

Roskin, K; Spearman, P. HIV-1 Broadly Neutralizing Antibodies Take the Road Less Traveled, and That Makes All the Difference. Cell Host and Microbe. 2020; 27:487-488.

Hoh, RA; Joshi, SA; Lee, J; Martin, BA; Varma, S; Kwok, S; Nielsen, SC A; Nejad, P; Haraguchi, E; Dixit, PS; Galli, SJ; Chinthrajah, RS; Nadeau, KC; Boyd, SD. Origins and clonal convergence of gastrointestinal IgE+ B cells in human peanut allergy. Science Immunology. 2020; 5.

Roskin, KM; Jackson, KJ L; Lee, J; Hoh, RA; Joshi, SA; Hwang, K; Bonsignori, M; Pedroza-Pacheco, I; Liao, H; Moody, MA; Fire, AZ; Borrow, P; Haynes, BF; Boyd, SD. Aberrant B cell repertoire selection associated with HIV neutralizing antibody breadth. Nature Immunology. 2020; 21:199-209.