Events in Normal Skin Promote Early-Life Atopic Dermatitis - The MPAACH Cohort: Jocelyn Biagini, PhD

Biagini’s manuscript published “Events in Normal Skin Promote Early-Life Atopic Dermatitis – The MPAACH Cohort” in The Journal of Allergy and Clinical Immunology: In Practice. The American Academy of Asthma Allergy and Immunology website highlighted this publication on April 14, 2020. Biagini describes the Mechanisms of Progression of Atopic Dermatitis to Asthma in Children (MPAACH) cohort, the first US-based early life prospective cohort of children with eczema. The goals of this NIH funded cohort are to define eczema phenotypes and endotypes, dissect the mechanisms that contribute to the development of allergic co-morbidities (food allergy, allergic rhinitis, and asthma) in children with eczema, and to identify novel biomarkers (immunologic, skin, biome, physiologic, genetic, genomic, epigenetic, and environmental) that identify children at high risk for the development of asthma and wheezing phenotypes, as well as other allergic conditions.

Air Pollution, Racial Disparities and COVID-19 Mortality: Tesfaye Mersha, PhD

The new Cincinnati Children's Research Horizons science blog features Mersha for his research published on August 1st, 2019 in the journal of Human Molecular Genetics entitled: “Air Pollution, Racial Disparities and COVID-19 Mortality”. This timely publication was a featured “circle plot” by the editors to serve as the issue’s cover art. The findings in this publication identified that because of long-standing structural racism and disparate experience with a range of socioeconomic and environmental factors, African Americans are at higher risk of dying from COVID-19 and many other health conditions, all worsened by chronic exposure to air pollution.

American Society of Human Genetics (ASHG) Career Development Committe: Tesfaye Mersha, PhD

Mersha received a nomination to serve on the American Society of Human genetics (ASHG) Career Development Committee. The ASHG Career Development Committee’s charge is to recommend and carryout activities related with the training and career development of ASHG members. The committee will guide career fairs, panels, and mentoring during training and early stage career periods.

Human Epidemiology and Response to SARS-CoV-2 Study (HEROS): Liza Bronner Murrison, PhD, MPH, and Gurjit Khurana Hershey, MD, PhD.

Bronner Murrison and Khurana Hershey are part of the innovative Human Epidemiology and Response to SARS-CoV-2 Study (HEROS), a longitudinal epidemiologic study of SARS-CoV-2 infection in children led by NIH-NIAID. The study aims to survey children for SARS-CoV-2 infection, including asymptomatic cases, to determine the rates of infection in 2000 children and their families enrolled from 18 US pediatric cohorts. The enrollment for our site is 310 children and their families to participate in HEROS from four of our pediatric asthma cohorts. This study is the first of its kind to use all remote recruiting with survey completion and sample collections performed by the families at home with support from our Cincinnati Children's HEROS team. The study will provide critical data during the pandemic to determine the prevalence of SARS-CoV-2 infection in children with and without asthma and other atopic conditions over a six month period.

Human Epidemiology and Response to SARS-CoV-2 Study (HEROS): Liza Bronner Murrison, PhD, MPH, and Gurjit Khurana Hershey, MD, PhD.

Bronner Murrison and Khurana Hershey are part of the innovative Human Epidemiology and Response to SARS-CoV-2 Study (HEROS), a longitudinal epidemiologic study of SARS-CoV-2 infection in children led by NIH-NIAID. The study aims to survey children for SARS-CoV-2 infection, including asymptomatic cases, to determine the rates of infection in 2000 children and their families enrolled from 18 US pediatric cohorts. The enrollment for our site is 310 children and their families to participate in HEROS from four of our pediatric asthma cohorts. This study is the first of its kind to use all remote recruiting with survey completion and sample collections performed by the families at home with support from our Cincinnati Children's HEROS team. The study will provide critical data during the pandemic to determine the prevalence of SARS-CoV-2 infection in children with and without asthma and other atopic conditions over a six month period.