Like most U.S. hospitals, Cincinnati Children's is affected by the IV fluid shortage caused by damage to Baxter International's North Carolina production facility during Hurricane Helene. Our teams will continue to watch this situation and will provide any updates as needed.
These findings suggest that DEP exposure results in accumulation of allergen-specific TH2/TH17 cells in the lungs, potentiating secondary allergen recall responses and promoting the development of allergic asthma.
This study identifies a biological basis for poor corticosteroid treatment response used to distinguish a subgroup of asthmatic children who respond poorly to systemic corticosteroid treatment. It concludes that VNN1 contributes to corticosteroid responsiveness, and changes in VNN1 nasal epithelial mRNA expression and VNN1 promoter methylation might be clinically useful biomarkers of treatment response in asthmatic children.
This study demonstrates that the underlying heterogeneity of asthma is likely due, in part, to distinct pathogenetic pathways that depend on preceding or comorbid overweight and/or allergy. It is therefore important to consider both obesity and asthma when conducting studies of asthma.
In this study, we sought to examine the association of TET1 methylation with asthma and traffic-related air pollution (TRAP). Our findings suggest a possible role of TET1 methylation in asthmatic patients and response to TRAP.