Theodosia A. Kalfa, MD, PhD
- Co-Director, Erythrocyte Diagnostic Laboratory
- Professor, UC Department of Pediatrics
- theodosia.kalfa@cchmc.org
- Board Certified
About
MD: Aristotle University Medical School, Thessaloniki, Greece, 1990.
PhD: Aristotle University Medical School, Thessaloniki, Greece, 1997.
Residency: University Of North Carolina, Chapel Hill, NC, 1999.
Fellowship: Duke University Medical Center, Durham, NC, 2003.
Certification: Hematology / oncology, American Board of Pediatrics, 2004; Pediatrics, American Board of Pediatrics, 2000; ECFMG Certification, 1995.
Licenses: Full and unrestricted medical license (OH Medical Board), 2003-present; full and unrestricted license of medical practice in Greece, 1990-present.
Services and Specialties
Cancer and Blood Diseases, Sickle Cell and Hemoglobin Disorders
Interests
Signaling in erythrocytes; erythropoiesis; sickle cell disease; reactive oxygen species
Research Areas
Experimental Hematology and Cancer Biology, Hematology, Cancer and Blood Diseases
Additional Languages
Greek
Insurance Information
Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.
Publications
VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. The American Journal of Human Genetics. 2020; 107:1149-1156.
Red cell membrane disorders: structure meets function. Blood. 2020; 136:1250-1261.
Signaling and cytoskeletal requirements in erythroblast enucleation. Blood. 2012; 119:6118-6127.
A pharmacokinetic-pharmacodynamic analysis of l-glutamine for the treatment of sickle cell disease: Implications for understanding the mechanism of action and evaluating response to therapy. British Journal of Haematology. 2024; 205:1147-1158.
Multicenter, phase 1 study of etavopivat (FT-4202) treatment for up to 12 weeks in patients with sickle cell disease. Blood Advances. 2024; 8:4459-4475.
Loss of TBC1D2B causes a progressive neurological disorder with gingival overgrowth. European Journal of Human Genetics. 2024; 32:558-566.
Rapid measurement of hemoglobin-oxygen dissociation by leveraging Bohr effect and Soret band bathochromic shift. The Analyst. 2024; 149:2561-2572.
Case report: Childhood erythrocytosis due to hypermanganesemia caused by homozygous SLC30A10 mutation. 2024; 3:1331485.
A Population Pharmacokinetic Analysis of L-Glutamine Exposure in Patients with Sickle Cell Disease: Evaluation of Dose and Food Effects. Clinical Pharmacokinetics. 2024; 63:357-365.
Diagnosis and management of pyruvate kinase deficiency: international expert guidelines. The Lancet Haematology. 2024; 11:e228-e239.
From the Blog
Blood Cell Production Discovery Opens Path to Improve Anemia of Inflammation
Theodosia A. Kalfa, MD, PhD10/31/2022
Rare Disease Day: More Tools for Solving Diagnostic Mysteries
Theodosia A. Kalfa, MD, PhD3/1/2021
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