Neuromuscular Development Group
Research Projects

How We Collaborate

In pursuit of our goal to accelerate research, the Neuromuscular Development Group meets weekly for discussion. These meetings include progress report presentations from trainees in each lab (on a rotational basis). We also meet monthly to specifically discuss research articles published by others which are of direct interest to the group.

In addition to the free exchange of ideas, the Neuromuscular Development Group encourages the exchange of techniques, mouse lines and reagents amongst its members to accelerate their research.

 

Projects (5)

Coordinated Mechanisms to Rescue Bioenergetics and Sarcopenia in Aging

This project aims at discovering myocyte-autonomous mechanisms to rescue energy and mass during muscle aging. We are leveraging the unprecedented anti-sarcopenic effects of a once-weekly intermittent glucocorticoid treatment to unveil actionable epigenetic/metabolic pathways across sexes and ages.

Collaborating Research Labs
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Millay LabMillay Lab
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Quattrocelli LabQuattrocelli Lab
Sensory Dysfunction in Muscular Dystrophy

This ongoing project is using animal models of muscular dystrophy (MDX) and analyzing sensory dysfunction using behavioral, physiological and genetic approaches.

Collaborating Research Labs
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Jankowski LabJankowski Lab
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Quattrocelli LabQuattrocelli Lab
Novel Functions of Immune Cells in Muscle Repair

We are analyzing how macrophages may establish synaptic-like contacts with myofibers to facilitate repair after damage. This project uses novel chemogenetic and optogenetic manipulations of macrophage function, and pairs these strategies with behavioral analyses, anatomical assessments of injured muscle and intravital calcium imaging assays.

Collaborating Research Labs
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Jankowski LabJankowski Lab
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Millay LabMillay Lab
Electrical Stimulation of Lumbar Afferents Restores Inspiratory Diaphragm Function in Mice after Spinal Cord Injury

This project aims to learn how to stimulate the sciatic nerve in mouse models of spinal cord injury.

Collaborating Research Labs
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Jankowski LabJankowski Lab
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Crone LabCrone Lab
Satellite Cell Dysregulation in Neuromuscular Contractures

This project investigates the behavior of satellite cells (muscle stem cells) in postnatal muscle growth following neonatal nerve injury involving the exchange of mouse strains and techniques.

Collaborating Research Labs
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Millay LabMillay Lab
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Cornwall / Goh LabCornwall / Goh Lab
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