MEG Study of Migraine Following Traumatic Brain Injury

The purpose of this study is to draw a link between the large existing migraine literature and the growing traumatic brain injury (TBI) literature by using magnetoencephalography (MEG) to determine the differences in  neural oscillations underlying acute and chronic TBI migraine.  Additionally, we will examine the differences between TBI and non-TBI migraines.

Based on previous migraine work, we expect i) acute TBI migraine to show abnormalities in a lower frequency range than chronic TBI migraines, and ii) spectral abnormalities following a task performed by TBI migraine patients will be delayed compared with those following a task performed by non-TBI patients. Establishing a biomarker of TBI migraines will provide a basis for the development of more targeted treatments for this public health problem, which yields very prevalent and severe consequences.