O'Donnell, A; Gonzalez, BA; Mukherjee, S; Wilson, R; Alfieri, CM; Swoboda, CO; Millay, DP; Zorn, AM; Yutzey, KE. Localized Prox1 Regulates Aortic Valve Endothelial Cell Diversity and Extracellular Matrix Stratification in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023; 43:1478-1493.

Velayutham, N; Calderon, MU; Alfieri, CM; Padula, SL; van Leeuwen, FN; Scheijen, B; Yutzey, KE. Btg1 and Btg2 regulate neonatal cardiomyocyte cell cycle arrest. Journal of Molecular and Cellular Cardiology. 2023; 179:30-41.

Uscategui Calderon, M; Gonzalez, BA; Yutzey, KE. Cardiomyocyte-fibroblast crosstalk in the postnatal heart. Frontiers in Cell and Developmental Biology. 2023; 11:1163331.

Xu, N; Yutzey, KE. Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome. JACC: Basic to Translational Science. 2022; 7:1143-1157.

Velayutham, N; Yutzey, KE. Porcine Models of Heart Regeneration. Journal of Cardiovascular Development and Disease. 2022; 9.

Padula, SL; Yutzey, KE. Epigenetic Regulation of Heart Failure: Cell Type Matters. Circulation Research. 2021; 129:414-416.

Hortells, L; Meyer, EC; Thomas, ZM; Yutzey, KE. Periostin-expressing Schwann cells and endoneurial cardiac fibroblasts contribute to sympathetic nerve fasciculation after birth. Journal of Molecular and Cellular Cardiology. 2021; 154:124-136.

Padula, SL; Velayutham, N; Yutzey, KE. Transcriptional Regulation of Postnatal Cardiomyocyte Maturation and Regeneration. International Journal of Molecular Sciences. 2021; 22.

Velayutham, N; Alfieri, CM; Agnew, EJ; Riggs, KW; Baker, RS; Ponny, SR; Zafar, F; Yutzey, KE. Cardiomyocyte cell cycling, maturation, and growth by multinucleation in postnatal swine. Journal of Molecular and Cellular Cardiology. 2020; 146:95-108.

O'Donnell, A; Yutzey, KE. Mechanisms of heart valve development and disease. Development (Cambridge). 2020; 147.

O'Donnell, A; Yutzey, KE. To EndoMT or Not to EndoMT: Zebrafish Heart Valve Development. Circulation Research. 2020; 126:985-987.

Xu, N; Gulick, J; Osinska, H; Yu, Y; McLendon, PM; Shay-Winkler, K; Robbins, J; Yutzey, KE. Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination. Circulation Research. 2020; 126:907-922.

Agnew, EJ; Velayutham, N; Ortiz, GM; Alfieri, CM; Hortells, L; Moore, V; Riggs, KW; Baker, RS; Gibson, AM; Ponny, SR; Alsaied, T; Zafar, F; Yutzey, KE. Scar Formation with Decreased Cardiac Function Following Ischemia/Reperfusion Injury in 1 Month Old Swine. Journal of Cardiovascular Development and Disease. 2020; 7.

Kim, AJ; Xu, N; Umeyama, K; Hulin, A; Ponny, SR; Vagnozzi, RJ; Green, EA; Hanson, P; McManus, BM; Nagashima, H; Yutzey, KE. Deficiency of Circulating Monocytes Ameliorates the Progression of Myxomatous Valve Degeneration in Marfan Syndrome. Circulation. 2020; 141:132-146.

Gomez-Stallons, MV; Hassel, K; Yutzey, KE. Developmental Pathways and Aortic Valve Calcification. Cardiovascular Calcification and Bone Mineralization. : Springer Nature; Springer Nature; 2020.

Gomez-Stallons, MV; Tretter, JT; Hassel, K; Gonzalez-Ramos, O; Amofa, D; Ollberding, NJ; Mazur, W; Choo, JK; Smith, JM; Kereiakes, DJ; Yutzey, KE. Calcification and extracellular matrix dysregulation in human postmortem and surgical aortic valves. Heart. 2019; 105:1616-1621.

Velayutham, N; Agnew, EJ; Yutzey, KE. Postnatal Cardiac Development and Regenerative Potential in Large Mammals. Pediatric Cardiology. 2019; 40:1345-1358.

Hortells, L; Johansen, AK Z; Yutzey, KE. Cardiac Fibroblasts and the Extracellular Matrix in Regenerative and Nonregenerative Hearts. Journal of Cardiovascular Development and Disease. 2019; 6.

Hulin, A; Hortells, L; Gomez-Stallons, MV; O'Donnell, A; Chetal, K; Adam, M; Lancellotti, P; Oury, C; Potter, SS; Salomonis, N; Yutzey, KE. Maturation of heart valve cell populations during postnatal remodeling. Development (Cambridge). 2019; 146.

Kim, AJ; Alfieri, CM; Yutzey, KE. Endothelial Cell Lineage Analysis Does Not Provide Evidence for EMT in Adult Valve Homeostasis and Disease. The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology. 2019; 302:125-135.

Hulin, A; Anstine, LJ; Kim, AJ; Potter, SJ; DeFalco, T; Lincoln, J; Yutzey, KE. Macrophage Transitions in Heart Valve Development and Myxomatous Valve Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 2018; 38:636-644.

Xiang, F; Fang, M; Yutzey, KE. Loss of β-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice. Nature Communications. 2017; 8:712.

Hulin, A; Moore, V; James, JM; Yutzey, KE. Loss of Axin2 results in impaired heart valve maturation and subsequent myxomatous valve disease. Cardiovascular Research (CVR). 2017; 113:40-51.

Gomez-Stallons, MV; Wirrig-Schwendeman, EE; Hassel, KR; Conway, SJ; Yutzey, KE. Bone Morphogenetic Protein Signaling Is Required for Aortic Valve Calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 2016; 36:1398-1405.

Xiang, F; Guo, M; Yutzey, KE. Overexpression of Tbx20 in Adult Cardiomyocytes Promotes Proliferation and Improves Cardiac Function After Myocardial Infarction. Circulation. 2016; 133:1081-1092.

Fang, M; Alfieri, CM; Hulin, A; Conway, SJ; Yutzey, KE. Loss of β-catenin promotes chondrogenic differentiation of aortic valve interstitial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 2014; 34:2601-2608.

Braitsch, CM; Kanisicak, O; van Berlo, JH; Molkentin, JD; Yutzey, KE. Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease. Journal of Molecular and Cellular Cardiology. 2013; 65:108-119.

Small, AM; Yutzey, KE; Binstadt, BA; Voigts Key, K; Bouatia-Naji, N; Milan, D; Aikawa, E; Otto, CM; St. Hilaire, C. Unraveling the Mechanisms of Valvular Heart Disease to Identify Medical Therapy Targets: A Scientific Statement From the American Heart Association. Circulation. 2024; 150:e109-e128.

Liu, Z; Liu, Y; Yu, Z; Tan, C; Pek, N; O’Donnell, A; Wu, A; Glass, I; Winlaw, DS; Guo, M; Spence, JR; Chen, YW; Yutzey, KE; Miao, Y; Gu, M. APOE–NOTCH axis governs elastogenesis during human cardiac valve remodeling. 2024; 3:933-950.

Xu, N; Alfieri, CM; Yu, Y; Guo, M; Yutzey, KE. Wnt Signaling Inhibition Prevents Postnatal Inflammation and Disease Progression in Mouse Congenital Myxomatous Valve Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 2024; 44:1540-1554.

Gonzalez, BA; Harmeyer, SW; Song, T; Sadayappan, S; Yutzey, KE. Dynamic changes in mitral valve extracellular matrix, tissue mechanics and function in a mouse model of Marfan syndrome. Matrix Biology. 2024; 126:1-13.

Xu, N; Gonzalez, BA; Yutzey, KE. Macrophage lineages in heart development and regeneration. . 2024.

O'Donnell, A; Yutzey, KE. Quality Over Quantity: BMP-9 Regulation of Scar Formation After Myocardial Infarction. JACC: Basic to Translational Science. 2023; 8:1331-1333.

Bowers, SL K; Meng, Q; Kuwabara, Y; Huo, J; Minerath, R; York, AJ; Sargent, MA; Prasad, V; Saviola, AJ; Galindo, DC; Hansen, KC; Vagnozzi, RJ; Yutzey, KE; Molkentin, JD. Col1a2-Deleted Mice Have Defective Type I Collagen and Secondary Reactive Cardiac Fibrosis with Altered Hypertrophic Dynamics. Cells. 2023; 12.

Ho, YC; Geng, X; O'Donnell, A; Ibarrola, J; Fernandez-Celis, A; Varshney, R; Subramani, K; Azartash-Namin, ZJ; Kim, J; Silasi, R; López-Andrés, N; Bischoff, J; Yutzey, KE; Srinivasan, RS. PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves. Circulation Research. 2023; 133:463-480.

Minerath, RA; Grimes, K; Kasam, RK; Sargent, M; York, A; Kuwabara, Y; Saviola, A; Alfieri, C; Hansen, K; Yutzey, KE; Molkentin, JD. Abstract P2106: Transforming Growth Factor β-dependent Regulation Of Cardiomyocyte Maturation. Circulation Research. 2023; 133.

Liu, Z; Liu, Y; Yu, Z; Pek, N; O'Donnell, A; Glass, I; Guo, M; Chen, Y; Wu, J; Yutzey, KE; Miao, Y; Gu, M. Abstract P1178: APOE-NOTCH Axis Governs Elastogenesis During Human Cardiac Valve Remodeling. Circulation Research. 2023; 133.

Xu, N; Alfieri, C; Yutzey, K. Abstract P1012: Wnt Signaling Is Required For Myxomatous Valve Disease In A Mouse Model Of Marfan Syndrome. Circulation Research. 2023; 133.

O'Donnell, A; Gonzalez, BA; Mukherjee, S; Wilson, R; Alfieri, CM; Swoboda, CO; Millay, DP; Zorn, AM; Yutzey, KE. Localized Prox1 Regulates Aortic Valve Endothelial Cell Diversity and Extracellular Matrix Stratification in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023; 43:1478-1493.

Velayutham, N; Calderon, MU; Alfieri, CM; Padula, SL; van Leeuwen, FN; Scheijen, B; Yutzey, KE. Btg1 and Btg2 regulate neonatal cardiomyocyte cell cycle arrest. Journal of Molecular and Cellular Cardiology. 2023; 179:30-41.

Uscategui Calderon, M; Gonzalez, BA; Yutzey, KE. Cardiomyocyte-fibroblast crosstalk in the postnatal heart. Frontiers in Cell and Developmental Biology. 2023; 11:1163331.

Liu, Z; Liu, Y; Yu, Z; O'Donnell, A; Guo, M; Chen, Y; Glass, I; Yutzey, K; Wu, J; Miao, Y; Gu, M. Abstract 9555: Human Valve Atlas in Health and Disease. Circulation. 2022; 146:a9555.

Xu, N; Yutzey, KE. Therapeutic CCR2 Blockade Prevents Inflammation and Alleviates Myxomatous Valve Disease in Marfan Syndrome. JACC: Basic to Translational Science. 2022; 7:1143-1157.

Xu, N; Yutzey, KE. Abstract P1112: Inhibition Of Wnt Signaling Protects Against Myxomatous Valve Disease In A Mouse Model Of Marfan Syndrome. Circulation Research. 2022; 131:ap1112.

Zarate, YA; Morris, SA; Blackshare, A; Algaze, CA; Connor, BS; Kim, AJ; Yutzey, KE; Miller, EM; Weaver, KN; Collins, RT. A clinical scoring system for early onset (neonatal) Marfan syndrome. Genetics in Medicine. 2022; 24:1503-1511.

Velayutham, N; Yutzey, KE. Porcine Models of Heart Regeneration. Journal of Cardiovascular Development and Disease. 2022; 9.

Auchampach, J; Han, L; Huang, GN; Kühn, B; Lough, JW; O’Meara, CC; Payumo, AY; Rosenthal, NA; Sucov, HM; Yutzey, KE; Patterson, M. Measuring cardiomyocyte cell-cycle activity and proliferation in the age of heart regeneration. American Journal of Physiology: Heart and Circulatory Physiology. 2022; 322:H579-H596.

Zarate, Y; Morris, S; Blackshare, A; Algaze, C; Connor, B; Kim, A; Yutzey, K; Miller, E; Weaver, KN; Collins, T. OP023: A clinical scoring system for early onset (neonatal) Marfan syndrome. Genetics in Medicine. 2022; 24:s353.

Padula, SL; Yutzey, KE. Epigenetic Regulation of Heart Failure: Cell Type Matters. Circulation Research. 2021; 129:414-416.

Hortells, L; Meyer, EC; Thomas, ZM; Yutzey, KE. Periostin-expressing Schwann cells and endoneurial cardiac fibroblasts contribute to sympathetic nerve fasciculation after birth. Journal of Molecular and Cellular Cardiology. 2021; 154:124-136.

Padula, SL; Velayutham, N; Yutzey, KE. Transcriptional Regulation of Postnatal Cardiomyocyte Maturation and Regeneration. International Journal of Molecular Sciences. 2021; 22.

Kim, AJ; Xu, N; Yutzey, KE. Macrophage lineages in heart valve development and disease. Cardiovascular Research (CVR). 2021; 117:663-673.

Peck, D; Tretter, J; Possner, M; Yutzey, K; Zafar, F; Morales, D; Alsaied, T. Timing of Repair in Tetralogy of Fallot: Effects on Outcomes and Myocardial Health. Cardiology in Review. 2021; 29:62-67.

Velayutham, N; Alfieri, CM; Agnew, EJ; Riggs, KW; Baker, RS; Ponny, SR; Zafar, F; Yutzey, KE. Cardiomyocyte cell cycling, maturation, and growth by multinucleation in postnatal swine. Journal of Molecular and Cellular Cardiology. 2020; 146:95-108.

Hortells, L; Valiente-Alandi, I; Thomas, ZM; Agnew, EJ; Schnell, DJ; York, AJ; Vagnozzi, RJ; Meyer, EC; Molkentin, JD; Yutzey, KE. A specialized population of Periostin-expressing cardiac fibroblasts contributes to postnatal cardiomyocyte maturation and innervation. Proceedings of the National Academy of Sciences of USA. 2020; 117:21469-21479.

O'Donnell, A; Yutzey, KE. Mechanisms of heart valve development and disease. Development (Cambridge). 2020; 147.

O'Donnell, A; Yutzey, KE. To EndoMT or Not to EndoMT: Zebrafish Heart Valve Development. Circulation Research. 2020; 126:985-987.

Xu, N; Gulick, J; Osinska, H; Yu, Y; McLendon, PM; Shay-Winkler, K; Robbins, J; Yutzey, KE. Ube2v1 Positively Regulates Protein Aggregation by Modulating Ubiquitin Proteasome System Performance Partially Through K63 Ubiquitination. Circulation Research. 2020; 126:907-922.

Agnew, EJ; Velayutham, N; Ortiz, GM; Alfieri, CM; Hortells, L; Moore, V; Riggs, KW; Baker, RS; Gibson, AM; Ponny, SR; Alsaied, T; Zafar, F; Yutzey, KE. Scar Formation with Decreased Cardiac Function Following Ischemia/Reperfusion Injury in 1 Month Old Swine. Journal of Cardiovascular Development and Disease. 2020; 7.

Yutzey, KE. Cytokinesis, Beta-Blockers, and Congenital Heart Disease. The New England Journal of Medicine. 2020; 382:291-293.

Kim, AJ; Xu, N; Umeyama, K; Hulin, A; Ponny, SR; Vagnozzi, RJ; Green, EA; Hanson, P; McManus, BM; Nagashima, H; Yutzey, KE. Deficiency of Circulating Monocytes Ameliorates the Progression of Myxomatous Valve Degeneration in Marfan Syndrome. Circulation. 2020; 141:132-146.

Gomez-Stallons, MV; Hassel, K; Yutzey, KE. Developmental Pathways and Aortic Valve Calcification. Cardiovascular Calcification and Bone Mineralization. : Springer Nature; Springer Nature; 2020.