Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery. Cell. 2023; 186:2062-2077.e17.
.Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion. Proceedings of the National Academy of Sciences of USA. 2022; 119:e2202490119.
.ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion. Developmental Cell. 2021; 56:3349-3363.e6.
.Skeletal muscle fibers count on nuclear numbers for growth. Seminars in Cell and Developmental Biology. 2021; 119:3-10.
.Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers. Nature Communications. 2020; 11:6374.
.Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains. Nature Communications. 2020; 11:6287.
.Myocyte-derived Myomaker expression is required for regenerative fusion but exacerbates membrane instability in dystrophic myofibers. JCI insight. 2020; 5.
.Myonuclear accretion is a determinant of exercise-induced remodeling in skeletal muscle. eLife. 2019; 8.
.Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development. Nature Communications. 2017; 8:15665.
.C16ORF70/MYTHO promotes healthy aging in C.elegans and prevents cellular senescence in mammals. The Journal of Clinical Investigation. 2024; 134.
.Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1α/Lipin1 axis in an aging-related sarcopenia model. The Journal of Clinical Investigation. 2024; 134.
.MEK1-ERK1/2 signaling regulates the cardiomyocyte non-sarcomeric actin cytoskeletal network. American Journal of Physiology: Heart and Circulatory Physiology. 2024; 326:H180-H189.
.Molecular regulation of myocyte fusion. Current Topics in Developmental Biology. 2024; 158:53-82.
.Expression of Myomaker and Myomerger in myofibers causes muscle pathology. Skeletal Muscle. 2023; 13:8.
.2023; 133.
. Abstract P2023: Mitogen-activated Protein Kinase-directed Modulation Of The Non-sarcomeric Actin Cytoskeleton In Cardiomyocytes. Circulation Research.Localized Prox1 Regulates Aortic Valve Endothelial Cell Diversity and Extracellular Matrix Stratification in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023; 43:1478-1493.
.Enveloped viruses pseudotyped with mammalian myogenic cell fusogens target skeletal muscle for gene delivery. Cell. 2023; 186:2062-2077.e17.
.Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion. Proceedings of the National Academy of Sciences of USA. 2022; 119:e2202490119.
.All for One and One for All: Regenerating Skeletal Muscle. Cold Spring Harbor perspectives in biology. 2022; 14.
.Regulation of the myoblast fusion reaction for muscle development, regeneration, and adaptations. Experimental Cell Research. 2022; 415:113134.
.ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion. Developmental Cell. 2021; 56:3349-3363.e6.
.TGFβ signaling curbs cell fusion and muscle regeneration. Nature Communications. 2021; 12:750.
.Fibroblast fusion to the muscle fiber regulates myotendinous junction formation. Nature Communications. 2021; 12:3852.
.Myomerger promotes fusion pore by elastic coupling between proximal membrane leaflets and hemifusion diaphragm. Nature Communications. 2021; 12:495.
.Comparing the epigenetic landscape in myonuclei purified with a PCM1 antibody from a fast/glycolytic and a slow/oxidative muscle. PLoS Genetics. 2021; 17:e1009907.
.Skeletal muscle fibers count on nuclear numbers for growth. Seminars in Cell and Developmental Biology. 2021; 119:3-10.
.FOXF1 is required for the oncogenic properties of PAX3-FOXO1 in rhabdomyosarcoma. Oncogene: Including Oncogene Reviews. 2021; 40:2182-2199.
.Single-nucleus RNA-seq identifies transcriptional heterogeneity in multinucleated skeletal myofibers. Nature Communications. 2020; 11:6374.
.Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains. Nature Communications. 2020; 11:6287.
.Myonuclear content regulates cell size with similar scaling properties in mice and humans. Nature Communications. 2020; 11:6288.
.DOCK3 is a dosage-sensitive regulator of skeletal muscle and Duchenne muscular dystrophy-associated pathologies. Human Molecular Genetics. 2020; 29:2855-2871.
.Myocyte-derived Myomaker expression is required for regenerative fusion but exacerbates membrane instability in dystrophic myofibers. JCI insight. 2020; 5.
.Lipid Mixing Assay for Murine Myoblast Fusion and Other Slow Cell-cell Fusion Processes. Bio-protocol. 2020; 10:e3544.
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