Publications

Research in the Liu Lab focuses on developing therapeutic strategies to stimulate CM proliferation, reversing cardiac remodeling, reducing cardiac fibrosis and improving cardiac function. Learn more about this research and our published findings.

Liu, S; Deshmukh, V; Wang, F; Liang, J; Cusick, J; Li, X; Martin, JF. Myocardial Infarction Suppresses Protein Synthesis and Causes Decoupling of Transcription and Translation. JACC: Basic to Translational Science. 2024; 9:792-807.

Li, RG; Li, X; Morikawa, Y; Grisanti-Canozo, FJ; Meng, F; Tsai, C; Zhao, Y; Liu, L; Kim, J; Xie, B; Klysik, E; Liu, S; Samee, MA H; Martin, JF. YAP induces a neonatal-like pro-renewal niche in the adult heart. 2024; 3:283-300.

Li, RG; Li, X; Grisanti-Canozo, F; Morikawa, Y; Meng, F; Kim, JH; Xie, B; Klysik, E; Liu, S; Samee, MA H; Martin, JF. Abstract P1068: Yap Induces A Neonatal Like Pro-renewal Niche In The Adult Heart. Circulation Research. 2023; 133.

Meng, F; Tsai, C; Kim, JH; Li, X; Steimle, J; Liu, S; Xie, B; Li, RG; Martin, JF. Abstract P2187: SARS-CoV2 Nonstructural Protein, But Not The Omicron Ba.4/5 Mutant, Suppresses YAP Transcriptional Activity In The Heart. Circulation Research. 2023; 133.

Liu, S; Deshmukh, V; Meng, F; Wang, Y; Morikawa, Y; Steimle, J; Li, RG; Wang, J; Martin, JF. Abstract P2006: Cardiac Cytoskeleton Sequesters Acetylated Yap In The Cytoplasm To Inhibit Cardiomyocyte Renewal After Myocardial Infarction. Circulation Research. 2023; 133.

Franklin, DA; Liu, S; Jin, A; Cui, P; Guo, Z; Arend, KC; Moorman, NJ; He, S; Wang, GG; Wan, YY; Zhang, Y. Ribosomal protein RPL11 haploinsufficiency causes anemia in mice via activation of the RP-MDM2-p53 pathway. The Journal of biological chemistry. 2023; 299:102739.

Zhang, S; Liu, S; Leach, JP; Li, K; Perin, EC; Martin, JF. Gene Therapy Knockdown of Hippo Signaling Resolves Arrhythmic Events in Pigs After Myocardial Infarction. Circulation. 2022; 146:1558-1560.

Liu, S; Deshmukh, V; Meng, F; Wang, J; Martin, J. Abstract P1010: Acetylation Regulates Yap Subcellular Localization In Heart Regeneration. Circulation Research. 2022; 131:ap1010.

Liu, S; Li, RG; Martin, JF. The cell-autonomous and non-cell-autonomous roles of the Hippo pathway in heart regeneration. Journal of Molecular and Cellular Cardiology. 2022; 168:98-106.

Liu, S; Martin, JF. RNA splicing to cytoskeleton: A new path to cardiomyocyte ploidy and division?. Developmental Cell. 2022; 57:945-946.

Liu, S; Tang, L; Zhao, X; Nguyen, B; Heallen, TR; Li, M; Wang, J; Wang, J; Martin, JF. Yap Promotes Noncanonical Wnt Signals From Cardiomyocytes for Heart Regeneration. Circulation Research. 2021; 129:782-797.

Liu, S; Li, K; Wagner Florencio, L; Tang, L; Heallen, TR; Leach, JP; Wang, Y; Grisanti, F; Willerson, JT; Perin, EC; Zhang, S; Martin, JF. Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction. Science Translational Medicine. 2021; 13.

Liu, Q; Pan, S; Liu, S; Zhang, S; Willerson, JT; Martin, JF; Dixon, RA F. Suppressing Hippo signaling in the stem cell niche promotes skeletal muscle regeneration. Stem Cells. 2021; 39:737-749.

Liu, S; Li, K; Heallen, T; Tang, L; Wang, Y; Wagner, L; Willerson, JT; Perin, EC; Zhang, S; Martin, JF. Abstract 293: Functional Recovery After Gene Therapy and Hippo Pathway Knock Down After Myocardial Infarction in a Pig Model. Circulation Research. 2020; 127.