Experimental Hematology and Cancer Biology

Publications

Abu-Shihab, Y; Nicolet, D; Mrózek, K; Routbort, M; Patel, KP; Walker, CJ; Buss, J; Stiff, A; Laganson, A; DiNardo, CD; Blachly, JS; Miles, LA; Eisfeld, A; Loghavi, S. BRAF-Mutated Acute Myeloid Leukemia (AML) Represents a Distinct, Prognostically Poor Subgroup Enriched in Myelodysplasia-Related (MR-)AML. Blood. 2023; 142:1575.

Adair, JE; Androski, L; Bayigga, L; Bazira, D; Brandon, E; Dee, L; Deeks, S; Draz, M; Dubé, K; Dybul, M; Nsubuga, MS; Tisdale, JF; Verhoeyen, E; Dropulic, B. Towards access for all: 1st Working Group Report for the Global Gene Therapy Initiative (GGTI). Gene Therapy (Basingstoke). 2023; 30:216-221.

Babic, I; Bryan, N; Cunningham, C; Sampson, A; Starczynowski, D; Nurmemmedov, E. Abstract 2759: Real-time cellular target engagement and protein quantification for drug discovery. Cancer Research. 2023; 83:2759.

Bennett, J; Ishikawa, C; Agarwal, P; Yeung, J; Sampson, A; Uible, E; Vick, E; Bolanos, LC; Hueneman, K; Wunderlich, M; Rosenbaum, J; Hoyt, SB; Thomas, CJ; Starczynowski, DT. Paralog-specific signaling by IRAK1/4 maintains MyD88-independent functions in MDS/AML. Blood. 2023; 142:989-1007.

Bewersdorf, JP; Xie, Z; Bejar, R; Borate, U; Boultwood, J; Brunner, AM; Buckstein, R; Carraway, HE; Churpek, JE; Daver, NG; Xu, ML; Savona, MR; Wei, AH; Zeidan, AM. Current landscape of translational and clinical research in myelodysplastic syndromes/neoplasms (MDS): Proceedings from the 1st International Workshop on MDS (iwMDS) Of the International Consortium for MDS (icMDS). Blood Reviews. 2023; 60:101072.

Bouffi, C; Wikenheiser-Brokamp, KA; Chaturvedi, P; Sundaram, N; Goddard, GR; Wunderlich, M; Brown, NE; Staab, JF; Latanich, R; Zachos, NC; Mulloy, JC; Zorn, AM; Wells, JM; Helmrath, MA. In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice. Nature Biotechnology. 2023; 41:824-831.

Butler-Foster, T; Khandelwal, A; Montemayor, C; Miller, YM; Yan, MT S; Holmberg, JA; Ipe, TS; Accooe, P; Cancelas, JA. From MPOX to the next epidemic: Words matter when talking about equity-deserving groups. Transfusion. 2023; 63:646-651.

Ceolan, J; Seu, K; Ntoumaziou, A; Elgammal, Y; Emberesh, S; Bilston, L; Richards, D; Dickerson, KE; Chonat, S; Rydz, N; Lutzko, C; Husami, A; Zhang, W; Kalfa, TA. Erythrocyte Disorders Mimicking Congenital Dyserythropoietic Anemia Based on Bone Marrow Pathology Exposed By Genetic Evaluation. Blood. 2023; 142:2459.

Chlon, TM; Patnaik, MM. Germline DDX41 mutant predisposition syndromes: Slow driver states to hematological malignancies. American Journal of Hematology. 2023; 98:1673-1676.

Chlon, TM; Stepanchick, E; Sulentic, A; Wilson, A; Starczynowski, DT. Abstract A46: Heterozygous mutations in DDX41 cause erythroid progenitor cell defects and cooperate with p53 mutations to cause hematologic malignancy. 2023; 4:a46.

Cochran, AE; Hassan, A; Hueneman, K; Choi, K; Starczynowski, DT. Defective Necroptosis Mediates Chemotherapy Resistance in AML. Blood. 2023; 142:1394.

Cullion, K; Ostertag-Hill, CA; Pan, M; Timko, B; Boscolo, E; Kohane, DS. Ablation of Venous Malformations by Photothermal Therapy with Intravenous Gold Nanoshells. Nano Letters: a journal dedicated to nanoscience and nanotechnology. 2023; 23:7092-7099.

Dandamudi, A; Akbar, H; Cancelas, J; Zheng, Y. Rho GTPase Signaling in Platelet Regulation and Implication for Antiplatelet Therapies. International Journal of Molecular Sciences. 2023; 24:2519.

Dandamudi, A; Seibel, W; Tourdot, B; Cancelas, JA; Akbar, H; Zheng, Y. Structure-Activity Relationship Analysis of Rhosin, a RhoA GTPase Inhibitor, Reveals a New Class of Antiplatelet Agents. International Journal of Molecular Sciences. 2023; 24:4167.

Dean, ST; Ishikawa, C; Zhu, X; Walulik, S; Nixon, T; Jordan, JK; Henderson, S; Wyder, M; Salomonis, N; Wunderlich, M; Greis, KD; Starczynowski, DT; Volk, AG. Repression of TRIM13 by chromatin assembly factor CHAF1B is critical for AML development. Blood Advances. 2023; 7:4822-4837.

Doherty, AC; Huddleston, DA; Horn, PS; Ratner, N; Simpson, BN; Schorry, EK; Aschbacher-Smith, L; Prada, CE; Gilbert, DL. Motor Function and Physiology in Youth With Neurofibromatosis Type 1. Pediatric Neurology. 2023; 143:34-43.

Dourson, AJ; Fadaka, AO; Warshak, AM; Paranjpe, A; Weinhaus, B; Queme, LF; Hofmann, MC; Evans, HM; Donmez, OA; Forney, C; Weirauch, MT; Kottyan, LT; Lucas, D; Deepe, GS; Jankowski, MP. Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming. 2023; 4:2023.02.13.528015.

Elgamal, OA; Zapata, JC; Li, H; Sharpe, C; Fobare, S; Stearns, B; Lerma, JR; Bryant, K; Furby, C; Long, M; Burd, A; Pauza, CD; Hertlein, EK; Byrd, JC. Therapeutic Targeting of FLT3 Gate Keeper Mutation with E2082-0047 in Traditional and a Novel Immunocompetent Murine Adoptive Transfer Model of AML. Blood. 2023; 142:1544.

Fan, C; Wunderlich, M; Cai, X; Yan, Z; Zhang, F; Davis, AK; Xu, L; Guo, F; Lu, QR; Azam, M; Tian, W; Zheng, Y. Kinase-independent role of mTOR and on-/off-target effects of an mTOR kinase inhibitor. Leukemia. 2023; 37:2073-2081.

Fichter, KM; Setayesh, T; Malik, P. Strategies for precise gene edits in mammalian cells. Molecular Therapy-Nucleic Acids. 2023; 32:536-552.

Filippi, MD. The multifaceted role of mitochondria in HSC fate decisions: energy and beyond. Experimental Hematology. 2023; 128:19-29.

Galletta, TJ; Lane, A; Lutzko, C; Leemhuis, T; Cancelas, JA; Khoury, R; Wang, YZ M; Hanley, PJ; Keller, MD; Bollard, CM; Davies, SM; Grimley, MS; Rubinstein, JD. Third-Party and Patient-Specific Donor-Derived Virus-Specific T Cells Demonstrate Similar Efficacy and Safety for Management of Viral Infections after Hematopoietic Stem Cell Transplantation in Children and Young Adults. Transplantation and cellular therapy. 2023; 29:305-310.

Garrett, MC; Albano, R; Carnwath, T; Elahi, L; Behrmann, CA; Pemberton, M; Woo, D; O’Brien, E; VanCauwenbergh, B; Perentesis, J; Roskin, K; Kornblum, H; Plas, DR; Lu, QR. HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma. Scientific Reports. 2023; 13:12433.

Gonzalez, LS; Fisher, AA; D'souza, SP; Cotella, EM; Lang, RA; Robinson, JE. Ventral striatum dopamine release encodes unique properties of visual stimuli in mice. eLife. 2023; 12:e85064.

Gonzalez-Muñoz, T; Giannatale, AD; García-Silva, S; Santos, V; Sanchez-Redondo, S; Savini, C; Graña-Castro, O; Blanco-Aparicio, C; Fischer, S; De Wever, O; Ratner, N; Yohay, K; Theuer, CP; Peinado, H. Endoglin, a Novel Biomarker and Therapeutical Target to Prevent Malignant Peripheral Nerve Sheath Tumor Growth and Metastasis. Clinical Cancer Research. 2023; 29:3744-3758.

Gorak, EJ; Otterstatter, M; Al Baghdadi, T; Gillis, N; Foran, JM; Liu, JJ; Bejar, R; Gore, SD; Kroft, SH; Harrington, A; Walker, ME; Padron, E; DeZern, AE; Sekeres, MA. Discordant pathologic diagnoses of myelodysplastic neoplasms and their implications for registries and therapies. Blood Advances. 2023; 7:6120-6129.

Gurska, LM; Okabe, R; Schurer, A; Tong, MM; Soto, M; Choi, D; Ames, K; Glushakow-Smith, S; Montoya, A; Tein, E; Levine, RL; Goel, S; Halmos, B; Gritsman, K. Crizotinib Has Preclinical Efficacy in Philadelphia-Negative Myeloproliferative Neoplasms. Clinical Cancer Research. 2023; 29:943-956.

Han, L; Dong, L; Leung, K; Zhao, Z; Li, Y; Gao, L; Chen, Z; Xue, J; Qing, Y; Li, W; Wei, M; Su, R; Chen, J; Deng, X. METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism. Cell Stem Cell. 2023; 30:52-68.e13.

Hashimoto, M; Li, J; Andreassen, PR; Huang, G. CPT1a Controls the Function of Long-Term Hematopoietic Stem Cells By Regulating the Balance between Fatty Acid Oxidation and Oxphos in Mitochondria. Blood. 2023; 142:4089.

Hegde, S; Nestheide, S; Wellndorf, A; Zheng, Y; Cancelas, J. 3080 – RHOA SIGNALING IS REQUIRED FOR THE COLD-INDUCED PLATELET LESION AND REVERSIBLE TARGETING OF RHOA IN A NEW PLATELET ADDITIVE SOLUTION EXTENDS DONOR-DERIVED PLATELET SHELF-LIFE TO FOURTEEN DAYS. Experimental Hematology. 2023; 124:s90.

Hennigan, RF; Thomson, CS; Stachowski, K; Nassar, N; Ratner, N. Merlin tumor suppressor function is regulated by PIP2-mediated dimerization. Editor, van der Wel P. PloS one. 2023; 18:e0281876.

Hu, X; Wu, X; Berry, K; Zhao, C; Xin, D; Ogurek, S; Liu, X; Zhang, L; Luo, Z; Sakabe, M; Lee, L; Hu, M; Xin, M; Lu, QR. Nuclear condensates of YAP fusion proteins alter transcription to drive ependymoma tumourigenesis. Nature Cell Biology. 2023; 25:323-336.

Ishikawa, C; Barreyro, L; Sampson, A; Hueneman, K; Choi, K; Bolanos, LC; Volk, A; Watowich, SS; Greis, K; Starczynowski, DT. UBE2N Regulates Oncoprotein Networks in Myeloid Malignancies. Blood. 2023; 142:2762.

Jackson, M; Ahmari, N; Wu, J; Rizvi, TA; Fugate, E; Kim, MO; Dombi, E; Arnhof, H; Boehmelt, G; Düchs, MJ; Long, CJ; Maier, U; Trapani, F; Hofmann, MH; Ratner, N. Combining SOS1 and MEK Inhibitors in a Murine Model of Plexiform Neurofibroma Results in Tumor Shrinkage. The Journal of pharmacology and experimental therapeutics. 2023; 385:106-116.

Katayama, KI; Zheng, Y; Inoue, N. Rac is required for the survival of cortical neurons. Experimental Neurology. 2023; 361:114316.

Koo, DJ; Reynaud, D; Ziady, A; Kahn, S; Abdullah, S; Luebbering, N; Strecker, L; Lake, KE; Giordullo, L; Ibrahimova, A; Good, S; Dandoy, DC E; Myers, K; Jodele, S; Davies, SM. 166 Reduced Sphingosine-1-Phosphate Leads to Hypoxemia and Lung Injury after Hematopoietic Stem Cell Transplant. Transplantation and cellular therapy. 2023; 29:s134.

Koo, J; Ziady, AG; Reynaud, D; Abdullah, S; Luebbering, N; Kahn, S; Langenberg, L; Strecker, L; Lake, K; Dandoy, CE; Siefert, ME; Skala, E; Jodele, S; Davies, SM. Increased Body Mass Index Augments Endothelial Injury and Clinical Outcomes after Hematopoietic Stem Cell Transplantation. Transplantation and cellular therapy. 2023; 29:704.e1-704.e8.

Laranjeira, AB A; Kong, T; Snyder, SC; Fulbright, MC; Fisher, DA C; Starczynowski, DT; Oh, ST. In Vivo Ablation of NFκB Cascade Effectors Alleviates Disease Burden in Myeloproliferative Neoplasms. Blood. 2023; 142:991.

LeBlanc, F; Bennett, J; Choi, K; Starczynowski, DT. Targeting CREB-Binding Protein (CREBBP) Overcomes Resistance to Azacitidine and Venetoclax Therapy in Acute Myeloid Leukemia (AML). Blood. 2023; 142:5765.

Li, J; Malouf, C; Miles, LA; Willis, MB; Pietras, EM; King, KY. Chronic inflammation can transform the fate of normal and mutant hematopoietic stem cells. Experimental Hematology. 2023; 127:8-13.

Li, J; Wu, Y; Xue, T; He, J; Zhang, L; Liu, Y; Zhao, J; Chen, Z; Xie, M; Xiao, B; Liu, N; Guo, F; Zhang, L; Zhang, L. Cdc42 signaling regulated by dopamine D2 receptor correlatively links specific brain regions of hippocampus to cocaine addiction. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. 2023; 1869:166569.

Li, Y; Martin, TE; Hancock, JM; Li, R; Viswanathan, S; Lydon, JP; Zheng, Y; Ye, X. Visualization of preimplantation uterine fluid absorption in mice using Alexa Fluor™ 488 Hydrazide†. Biology of Reproduction. 2023; 108:204-217.

Li, Y; Xue, M; Deng, X; Dong, L; Nguyen, LX T; Ren, L; Han, L; Li, C; Xue, J; Zhao, Z; Tian, J; Shen, B; Su, R; Chen, J. TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal. Cell Stem Cell. 2023; 30:1072-1090.e10.

Lin, Y; Zhao, X; Liou, B; Fannin, V; Zhang, W; Liu, Y; Wang, X; Pan, D; Grabowski, G; Liu, C; Sun, Y. Earlier-onset, more severe neurodegeneration in PGRN KO mice with a decreased dose of D409V Gba1. Molecular Genetics and Metabolism. 2023; 138:107207.

Lin, Y; Zheng, Y. Rho Family GTPases and their Modulators. NADPH Oxidases Revisited: From Function to Structure. : Springer Nature; Springer Nature; 2023.

Liu, X; Sato, N; Yabushita, T; Li, J; Jia, Y; Tamura, M; Asada, S; Fujino, T; Fukushima, T; Yonezawa, T; Shibata, T; Miyake, K; Kitamura, T; Goyama, S. IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia. EMBO Molecular Medicine. 2023; 15:e15631.

Lu, R; Luo, Z. MDB-02. NUCLEAR ENVELOPE PHOSPHATASE CTDNEP1 MUTATIONS POTENTIATE AGGRESSIVE MEDULLOBLASTOMA BY TRIGGERING MYC ACTIVATION AND GENOMIC INSTABILITY. Neuro-Oncology. 2023; 25:i61-i62.

Luo, Z; Lu, R. MDB-05. HUMAN FETAL CEREBELLAR CELL ATLAS INFORMS MEDULLOBLASTOMA ORIGIN AND ONCOGENESIS. Neuro-Oncology. 2023; 25:i62.

Luo, Z; Xin, D; Liao, Y; Berry, K; Ogurek, S; Zhang, F; Zhang, L; Zhao, C; Rao, R; Dong, X; Zhou, W; Weiss, WA; Andreassen, P; Lu, QR. Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability. Nature Communications. 2023; 14:762.

Magallón-Lorenz, M; Terribas, E; Ortega-Bertran, S; Creus-Bachiller, E; Fernández, M; Requena, G; Rosas, I; Mazuelas, H; Uriarte-Arrazola, I; Negro, A; Reuss, D; Carrió, M; Gel, B; Serra, E. Deep genomic analysis of malignant peripheral nerve sheath tumor cell lines challenges current malignant peripheral nerve sheath tumor diagnosis. iScience. 2023; 26:106096.

Marion, W; Koppe, T; Chen, CC; Wang, D; Frenis, K; Fierstein, S; Sensharma, P; Aumais, O; Peters, M; Ruiz-Torres, S; Ebert, BL; Starczynowski, D; da Rocha, EL; Rowe, RG. RUNX1 mutations mitigate quiescence to promote transformation of hematopoietic progenitors in Fanconi anemia. Leukemia. 2023; 37:1698-1708.

Matsui, S; Ri, C; Bolanos, LC; Choi, K; Shibamiya, A; Ishii, A; Takaishi, K; Oshima-Hasegawa, N; Tsukamoto, S; Takeda, Y; Mimura, N; Yokote, K; Starczynowski, DT; Sakaida, E; Muto, T. Regulation of Metabolic Homeostasis By TRAF6 Contributes to the Leukemia Progression. Blood. 2023; 142:1370.

McDonald, CL; Qasba, P; Anderson, DG; Bao, G; Colvin, RA; Kohn, DB; Malik, P; Mitchell, MJ; Pu, WT; Rawlings, DJ; Williams, DA; Flotte, TR. Future Directions and Resource Needs for National Heart, Lung, and Blood Institute (NHLBI) Gene Therapy Research: A Report of an NHLBI Workshop. Human Gene Therapy. 2023; 34:83-89.

Menéndez-Gutiérrez, MP; Porcuna, J; Nayak, R; Paredes, A; Niu, H; Núñez, V; Paranjpe, A; Gómez, MJ; Bhattacharjee, A; Schnell, DJ; Sánchez-Cabo, F; Welch, JS; Salomonis, N; Cancelas, JA; Ricote, M. Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis. Blood. 2023; 141:592-608.

Modur, V; Muhammad, B; Yang, JQ; Zheng, Y; Komurov, K; Guo, F. Mechanism of inert inflammation in an immune checkpoint blockade-resistant tumor subtype bearing transcription elongation defects. Cell Reports. 2023; 42:112364.

Muto, T; Walker, CS; Agarwal, P; Vick, E; Sampson, A; Choi, K; Niederkorn, M; Ishikawa, C; Hueneman, K; Varney, M; Starczynowski, DT. Inactivation of p53 provides a competitive advantage to del(5q) myelodysplastic syndrome hematopoietic stem cells during inflammation. Haematologica: the hematology journal. 2023; 108:2715-2729.

Na, Y; Hall, A; Yu, Y; Hu, L; Choi, K; Burgard, JA; Szabo, S; Huang, G; Ratner, N; Wu, J. Runx1/3-driven adaptive endoplasmic reticulum stress pathways contribute to neurofibromagenesis. Oncogene: Including Oncogene Reviews. 2023; 42:1038-1047.

Neidemire-Colley, LM; Khanal, S; Braunreiter, KM; Snyder, KJ; Gao, Y; Kalyan, S; Kararoud, MN; Duszynsk, M; Chi, M; Malik, P; Choe, H; Garzon, R; Ranganathan, P. CRISPR/Cas9 Gene Editing of MIR155HG in Primary Human T Cells to Prevent Acute Graft-Versus-Host Disease. Journal of immunology (Baltimore, Md. : 1950). 2023; 210:173.21.

Ottesen, EW; Singh, NN; Luo, D; Kaas, B; Gillette, BJ; Seo, J; Jorgensen, HJ; Singh, RN. Diverse targets of SMN2-directed splicing-modulating small molecule therapeutics for spinal muscular atrophy. Nucleic Acids Research. 2023; 51:5948-5980.

Pillay-Smiley, N; Fletcher, JS; de Blank, P; Ratner, N. Shedding New Light: Novel Therapies for Common Disorders in Children with Neurofibromatosis Type I. Pediatric Clinics of North America. 2023; 70:937-950.

Radulovic, I; Schündeln, MM; Müller, L; Ptok, J; Honisch, E; Niederacher, D; Wiek, C; Scheckenbach, K; Leblanc, T; Larcher, L; Soulier, J; Reinhardt, D; Schaal, H; Andreassen, PR; Hanenberg, H. A novel cancer risk prediction score for the natural course of FA patients with biallelic BRCA2/FANCD1 mutations. Human Molecular Genetics. 2023; 32:1836-1849.

Ratner, N; Hu, L; Pundavela, J; Epstein, JA. Abstract IA17: Use of RAS isoforms in nerve tumors. Molecular cancer research : MCR. 2023; 21:ia17.

Robinson, TM; Bowman, RL; Persaud, S; Liu, Y; Neigenfind, R; Gao, Q; Zhang, J; Sun, X; Miles, LA; Cai, SF; Dogan, A; Roshal, M; Levine, RL; Xiao, W. Single-cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia. Science Advances. 2023; 9:eadg0488.

Rosenbaum, JS; Kolt, AS; Hoyt, SB; Hayes, GM; Soldo, BL; Thomas, CJ; Starczynowski, DT. Kme-0584, a Highly Potent IRAK1/IRAK4/panFLT3 Inhibitor, Is a Promising Clinical Candidate for Hypomethylating Agent Plus Venetoclax Resistant AML/MDS Patients. Blood. 2023; 142:4152.

Schrenk, S; Bischoff, LJ; Goines, J; Cai, Y; Vemaraju, S; Odaka, Y; Good, SR; Palumbo, JS; Szabo, S; Reynaud, D; Van Raamsdonk, CD; Lang, RA; Boscolo, E. MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ. Nature Communications. 2023; 14:1929.

Schwede, M; Jahn, K; Miles, LA; Bowman, RL; Kuipers, J; Robinson, TM; Ediriwickrema, A; Gentles, AJ; Levine, R; Beerenwinkel, N; Takahashi, K; Majeti, R. Abstract A49: Characterizing the order of mutation acquisition in acute myeloid leukemia using large-scale single-cell sequencing. 2023; 4:a49.

Singh, AK; Prasad, P; Cancelas, JA. Mesenchymal stromal cells, metabolism, and mitochondrial transfer in bone marrow normal and malignant hematopoiesis. Frontiers in Cell and Developmental Biology. 2023; 11:1325291.

Stahl, M; Abdel-Wahab, O; Wei, AH; Savona, MR; Xu, ML; Xie, Z; Taylor, J; Starczynowski, D; Sanz, GF; Sallman, DA; Steensma, DP; Sekeres, MA; Buckstein, RJ; Zeidan, AM. An agenda to advance research in myelodysplastic syndromes: a TOP 10 priority list from the first international workshop in MDS. Blood Advances. 2023; 7:2709-2714.

Stahl, M; Bewersdorf, JP; Xie, Z; Porta, MG D; Komrokji, R; Xu, ML; Abdel-Wahab, O; Taylor, J; Steensma, DP; Starczynowski, DT; Wei, AH; Santini, V; Savona, MR; Zeidan, AM. Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS). Blood Reviews. 2023; 62:101128.

Stahl, M; Derkach, A; Farnoud, N; Bewersdorf, JP; Robinson, T; Famulare, C; Cho, C; Devlin, S; Menghrajani, K; Patel, MA; Papaemmanuil, E; Tallman, MS; Roshal, M; Goldberg, AD. Molecular predictors of immunophenotypic measurable residual disease clearance in acute myeloid leukemia. American Journal of Hematology. 2023; 98:79-89.

Starczynowski, DT. 1031 – FROM PRE-LEUKEMIC STATES TO MALIGNANT TRANSFORMATION: UNRAVELING THE ROLE OF DYSREGULATED INNATE IMMUNE SIGNALING AND INFLAMMATION IN MYELOID MALIGNANCIES. Experimental Hematology. 2023; 124:s35.

Talley, MJ; Nardini, D; Ehrman, LA; Lu, QR; Waclaw, RR. Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon. Neural Development. 2023; 18:5.

Tamang, HK; Stringham, EN; Tourdot, BE. Platelet Functional Testing Via High-Throughput Microtiter Plate-Based Assays. 2023; 3:e668.

Thant, M; Cancelas, J; Kaplan, A. The enhanced direct antiglobulin test in current practice has a limited impact on management of adult patients. Transfusion and Apheresis Science. 2023; 62:103768.

Thompson, M; Sakabe, M; Verba, M; Hao, J; Meadows, SM; Lu, QR; Xin, M. PRDM16 regulates arterial development and vascular integrity. Frontiers in Physiology. 2023; 14:1165379.

Thompson, M; Sakabe, M; Xin, M. Abstract 664: Essential Roles Of Prdm16 In Repression Of Venous Marker In The Artery. Arteriosclerosis, Thrombosis, and Vascular Biology. 2023; 43.

Treichel, S; Filippi, MD. Linking cell cycle to hematopoietic stem cell fate decisions. Frontiers in Cell and Developmental Biology. 2023; 11:1231735.

Uible, EE; Choi, K; Hueneman, K; Bolanos, LC; Greis, K; Starczynowski, DT. The Zymogen Form of Caspase-1 Is Required to Fine Tune Excessive Cell-Intrinsic Inflammation in Acute Myeloid Leukemia. Blood. 2023; 142:1391.

Verma, R; Chen, X; Xin, D; Luo, Z; Ogurek, S; Xin, M; Rao, R; Berry, K; Lu, QR. Olig1/2-Expressing Intermediate Lineage Progenitors Are Predisposed to PTEN/p53-Loss-Induced Gliomagenesis and Harbor Specific Therapeutic Vulnerabilities. Cancer Research. 2023; 83:890-905.

Vick, EJ; Bennett, J; Cochran, AE; Hueneman, K; Bolanos, LC; Zhang, X; McKnight, C; Ceribelli, M; Klumpp-Thomas, C; Choi, K; Greis, K; Thomas, CJ; Starczynowski, DT. Synthetic Lethal Interactions with IRAK4 Inhibition in Myeloid Malignancies. Blood. 2023; 142:45.

Walulik, S; Dean, S; Vick, EJ; Zhu, X; Wunderlich, M; Chou, C; Choi, K; Grimes, HL; Starczynowski, DT; Miles, LA; Volk, A. The Mechanism of Therapy Resistance By Lineage Plasticity in AML and How to Overcome It. Blood. 2023; 142:1410.

Wang, C; Tu, Z; Cai, X; Wang, W; Davis, AK; Nattamai, K; Paranjpe, A; Dexheimer, P; Wu, J; Huang, FL; Geiger, H; Huang, G; Zheng, Y. A critical role of RUNX1 in governing megakaryocyte-primed hematopoietic stem cell differentiation. Blood Advances. 2023; 7:2590-2605.

Wang, C; Zheng, Y; Fan, C; Tu, Z; Cai, X; Wu, J; Huang, G. Conserved and Unique Regulatory Mechanisms of RUNX1 in Hematopoietic Stem/Progenitor Cell Subpopulations in Both Normal Hematopoiesis and FPD/AML Development. Blood. 2023; 142:1314.

Wang, F; Wang, W; Gu, S; Qi, D; Smith, NA; Peng, W; Dong, W; Yuan, J; Zhao, B; Mao, Y; Shapiro, LA; Yi, SS; Wu, E; Huang, JH. Distinct astrocytic modulatory roles in sensory transmission during sleep, wakefulness, and arousal states in freely moving mice. Nature Communications. 2023; 14:2186.

Xia, B; Liu, Y; Wang, J; Lu, Q; Lv, X; Deng, K; Yang, J. Emerging role of exosome-shuttled noncoding RNAs in gastrointestinal cancers: From intercellular crosstalk to clinical utility. Pharmacological Research. 2023; 195:106880.

Xie, Z; Starczynowski, DT. Are DDX41 variants of unknown significance and pathogenic variants created equal?. Haematologica: the hematology journal. 2023; 108:2883-2885.

Yamaguchi, A; van Hoorebeke, C; Tourdot, BE; Perry, S; Lee, G; Rhoads, N; Rickenberg, A; Green, A; Sorrentino, J; Yeung, J; Freedman, JC; Holman, TR; Holinstat, M. Fatty acids negatively regulate platelet function through formation of noncanonical 15-lipoxygenase-derived eicosanoids. Pharmacology Research and Perspectives. 2023; 11:e01056.

Yoshimatsu, S; Okahara, J; Yoshie, J; Igarashi, Y; Nakajima, R; Sanosaka, T; Qian, E; Sato, T; Kobayashi, H; Morimoto, S; Kishi, N; Pillis, DM; Malik, P; Noce, T; Okano, H. Generation of a tyrosine hydroxylase-2A-Cre knockin non-human primate model by homology-directed-repair-biased CRISPR genome editing. Cell Reports: Methods. 2023; 3:100590.

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