We serve as the basic research arm of the Cancer and Blood Diseases Institute, which is ranked No. 2 in the nation for pediatric cancer care in the U.S. News & World Report 2026-2027 Best Children's Hospitals rankings.

Our Research

For over two decades, our division has focused on basic and translational research in blood cells and cancer. We examine how abnormalities in the genetic code and cell signaling pathways contribute to the development of cancer and blood diseases within the context of regulatory mechanisms in normal cell and tissue physiology. This foundational work paves the way for new approaches to diagnosis, treatment and cure for some of the most serious pediatric diseases.

Our division prides itself on fostering a highly collaborative environment. Not only do we promote multidisciplinary research with other divisions at Cincinnati Children’s, but we also collaborate with institutions worldwide.

We also serve as a Cincinnati Center of Excellence in Molecular Hematology, funded by the National Institutes of Health (NIH).

Basic Research Programs

Our research is focused on eight thematic programs. Each program seeks to understand the mechanisms and develop novel therapies associated with clinical programs in these areas:

• Brain Tumor
• Cancer Biology and Neural Tumors
• Hemangioma and Vascular Malformations
• Hematological Malignancy
• Hematology and Gene Therapy
• Hemostasis and Thrombosis
• Signaling and Drug Discovery
• Stem Cell

Nurturing the Next Generation of Scientists and Clinicians

Dedicated mentoring and training programs ensure the professional growth of team members and trainees—the future leaders in cancer and molecular hematology research. Aspiring scientists may apply for pre- and postdoctoral fellowships.