Winter Storm Update

Due to the winter storm, in-person outpatient appointments scheduled on Monday, Jan. 6 before 10 am are cancelled and will be rescheduled. Surgery, radiology and dental appointments with anesthesia or sedation are being reviewed and some may be rescheduled.

Additional closures may be necessary. Please check back often.

Full Closure Details

Developmental Biology
Xue Lab

Bioengineering Techniques for the Future of Organoid Generation

The goal of the Xue lab is to create miniature human organs using stem cells to unravel disease mechanism, improve drug development, and advance personalized regenerative medicine. Specifically, we develop various bioengineering techniques to precisely control the environment of stem cells, including microfluidics, 3D bioprinting, optogenetics, and cell mechanics tools. Through these methods, we aim to guide stem cell pattern formation and morphogenesis to build the next generation human organoids with high reproducibility, complexity, and fidelity.

We are particularly interested in developing bioengineered human neural organoids which recapitulate the dynamic formation of different neural regions and neural circuits to study the inter-regional interactions.

Meet the PI

Xufeng Xue, PhD

Assistant Professor, UC Department of Pediatrics

I am an assistant professor within the Division of Developmental Biology and Center for Stem Cell & Organoid Medicine (CuSTOM). I joined Cincinnati Children’s in 2024 and focus my research on bioengineered human organoids.

Read My Full Web Bio

Winter Storm Update

Developmental BiologyXue Lab

Bioengineering Techniques for the Future of Organoid Generation

Meet the PI

Xufeng Xue, PhD

Connect With Us

Developmental Biology
Xue Lab