Best of Our Research

Publications

Kliewer, KL; Murray-Petzold, C; Collins, MH; Abonia, JP; Bolton, SM; DiTommaso, LA; Martin, LJ; Zhang, X; Mukkada, VA; Putnam, PE; Lyles, JL; Shoda, T; Klion, AD; Rothenberg, ME. Benralizumab for eosinophilic gastritis: a single-site, randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Gastroenterology and Hepatology. 2023; 8:803-815.

Kliewer, KL; Gonsalves, N; Dellon, ES; Katzka, DA; Abonia, JP; Aceves, SS; Arva, NC; Besse, JA; Bonis, PA; Caldwell, JM; Yang, GY; Zhang, X; Furuta, GT; Rothenberg, ME. One-food versus six-food elimination diet therapy for the treatment of eosinophilic oesophagitis: a multicentre, randomised, open-label trial. The Lancet Gastroenterology and Hepatology. 2023; 8:408-421.

Shoda, T; Rochman, M; Collins, MH; Caldwell, JM; Mack, LE; Osswald, GA; Mukkada, VA; Putnam, PE; Rothenberg, ME. Molecular analysis of duodenal eosinophilia. Journal of Allergy and Clinical Immunology. 2023; 151:1027-1039.

Zhang, S; Shoda, T; Aceves, SS; Arva, NC; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; Gonsalves, N; Gupta, SK; Wechsler, JB; Yang, GY; Furuta, GT; Rothenberg, ME. Mast cell-pain connection in eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2022; 77:1895-1899.

Shoda, T; Collins, MH; Rochman, M; Wen, T; Caldwell, JM; Mack, LE; Osswald, GA; Besse, JA; Haberman, Y; Aceves, SS; Mingler, M; Minnicozzi, M; Muir, A; Murray-Petzold, C. Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology. 2022; 162:1635-1649.

Min, S; Shoda, T; Wen, T; Rothenberg, ME. Diagnostic merits of the Eosinophilic Esophagitis Diagnostic Panel from a single esophageal biopsy. Journal of Allergy and Clinical Immunology. 2022; 149:782-787.e1.

Shoda, T; Wen, T; Caldwell, JM; Ben-Baruch Morgenstern, N; Osswald, GA; Rochman, M; Mack, LE; Felton, JM; Abonia, JP; Arva, NC; Mingler, M; Minnicozzi, M; Muir, A; MurrayPetzold, C. Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Gastroenterology. 2022; 162:439-453.

Shoda, T; Kaufman, KM; Wen, T; Caldwell, JM; Osswald, GA; Purnima, P; Zimmermann, N; Collins, MH; Rehn, K; Foote, H; Mukkada, VA; Putnam, PE; Martin, LJ; Rothenberg, ME. Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis. Nature Communications. 2021; 12:6795.

Shoda, T; Wen, T; Caldwell, JM; Collins, MH; Besse, JA; Osswald, GA; Abonia, JP; Arva, NC; MDd, DA; Capocelli, KE; Aceves, SS; Furuta, GT; Rothenberg, ME; Gastrointe, CE. Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study. Journal of Allergy and Clinical Immunology. 2020; 145:255-269.

Shoda, T; Wen, T; Aceves, SS; Abonia, JP; Atkins, D; Bonis, PA; Caldwell, JM; Capocelli, KE; Carpenter, CL; Collins, MH; Zimmermann, N; Furuta, GT; Rothenberg, ME; Gastrointe, CE. Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. The Lancet Gastroenterology and Hepatology. 2018; 3:477-488.

Sato, H; Dellon, ES; Aceves, SS; Arva, NC; Chehade, M; Collins, MH; Davis, CM; Falk, GW; Furuta, GT; Gonsalves, NP; Wechsler, JB; Yang, GY; Rothenberg, ME; Shoda, T. Clinical and molecular correlates of the Index of Severity for Eosinophilic Esophagitis. Journal of Allergy and Clinical Immunology. 2024; 154:375-386.e4.

Sato, H; Taylor, RJ; Sakai, N; Osonoi, K; Rothenberg, ME; Shoda, T. Eosinophil Involvement Outside the Esophagus in Eosinophilic Esophagitis. Clinical Gastroenterology and Hepatology. 2024; 22:1531-1534.e2.

Shoda, T; Taylor, RJ; Sakai, N; Rothenberg, ME. Common and disparate clinical presentations and mechanisms in different eosinophilic gastrointestinal diseases. Journal of Allergy and Clinical Immunology. 2024; 153:1472-1484.

Ruffner, MA; Shoda, T; Lal, M; Mrozek, Z; Muir, AB; Spergel, JM; Dellon, ES; Rothenberg, ME. Persistent esophageal changes after histologic remission in eosinophilic esophagitis. Journal of Allergy and Clinical Immunology. 2024; 153:1063-1072.

Rochman, M; Rochman, Y; Caldwell, JM; Mack, LE; Besse, JA; Manes, NP; Yoon, SH; Shoda, T; Nita-Lazar, A; Rothenberg, ME. The minichromosome maintenance complex drives esophageal basal zone hyperplasia. JCI insight. 2023; 8.

Kliewer, KL; Murray-Petzold, C; Collins, MH; Abonia, JP; Bolton, SM; DiTommaso, LA; Martin, LJ; Zhang, X; Mukkada, VA; Putnam, PE; Lyles, JL; Shoda, T; Klion, AD; Rothenberg, ME. Benralizumab for eosinophilic gastritis: a single-site, randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet Gastroenterology and Hepatology. 2023; 8:803-815.

Gonsalves, N; Doerfler, B; Zalewski, A; Yang, GY; Martin, LJ; Zhang, X; Shoda, T; Brusilovsky, M; Aceves, S; Thompson, K; Rudman Spergel, AK; Furuta, G; Rothenberg, ME; Hirano, I. Prospective study of an amino acid-based elemental diet in an eosinophilic gastritis and gastroenteritis nutrition trial. Journal of Allergy and Clinical Immunology. 2023; 152:676-688.

Aknin, E; Larey, A; Caldwell, JM; Collins, MH; Rothenberg, ME; Savir, Y. (2023) Harnessing Digital Pathology And Causal Learning To Improve Eosinophilic Esophagitis Dietary Treatment Assignment. Institute of Electrical and Electronics Engineers (IEEE). 00:1-8.

Ben-Baruch Morgenstern, N; Shoda, T; Rochman, Y; Caldwell, JM; Collins, MH; Mukkada, V; Putnam, PE; Bolton, SM; Felton, JM; Rochman, M; Murray-Petzold, C; Kliewer, KL; Rothenberg, ME. Local type 2 immunity in eosinophilic gastritis. Journal of Allergy and Clinical Immunology. 2023; 152:136-144.

Kliewer, KL; Gonsalves, N; Dellon, ES; Katzka, DA; Abonia, JP; Aceves, SS; Arva, NC; Besse, JA; Bonis, PA; Caldwell, JM; Yang, GY; Zhang, X; Furuta, GT; Rothenberg, ME. One-food versus six-food elimination diet therapy for the treatment of eosinophilic oesophagitis: a multicentre, randomised, open-label trial. The Lancet Gastroenterology and Hepatology. 2023; 8:408-421.

Brusilovsky, M; Rochman, M; Shoda, T; Kotliar, M; Caldwell, JM; Mack, LE; Besse, JA; Chen, X; Weirauch, MT; Barski, A; Rothenberg, ME. Vitamin D receptor and STAT6 interactome governs oesophageal epithelial barrier responses to IL-13 signalling. Gut. 2023; 72:834-845.

Sato, H; Osonoi, K; Sharlin, CS; Shoda, T. Genetic and Molecular Contributors in Eosinophilic Esophagitis. Current Allergy and Asthma Reports. 2023; 23:255-266.

Shoda, T; Rochman, M; Collins, MH; Caldwell, JM; Mack, LE; Osswald, GA; Mukkada, VA; Putnam, PE; Rothenberg, ME. Molecular analysis of duodenal eosinophilia. Journal of Allergy and Clinical Immunology. 2023; 151:1027-1039.

Alvarado, D; Lu, Y; Shoda, T; Caldwell, JM; Keler, T; Rothenberg, ME. Strong association of mast cells with eosinophilic esophagitis-specific signatures. Allergy: European Journal of Allergy and Clinical Immunology. 2023; 78:583-586.

Avlas, S; Shani, G; Rhone, N; Itan, M; Dolitzky, A; Hazut, I; Grisaru-Tal, S; Gordon, Y; Shoda, T; Ballaban, A; Benhar, I; Varol, C; Rothenberg, ME; Munitz, A. Epithelial cell-expressed type II IL-4 receptor mediates eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2023; 78:464-476.

Ben-Baruch Morgenstern, N; Ballaban, AY; Wen, T; Shoda, T; Caldwell, JM; Kliewer, K; Felton, JM; Abonia, JP; Mukkada, VA; Putnam, PE; Bolton, SM; Dwyer, DF; Barrett, NA; Rothenberg, ME. Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation, and activation that persists in remission. Journal of Allergy and Clinical Immunology. 2022; 149:2062-2077.

Zhang, S; Shoda, T; Aceves, SS; Arva, NC; Chehade, M; Collins, MH; Dellon, ES; Falk, GW; Gonsalves, N; Gupta, SK; Wechsler, JB; Yang, GY; Furuta, GT; Rothenberg, ME. Mast cell-pain connection in eosinophilic esophagitis. Allergy: European Journal of Allergy and Clinical Immunology. 2022; 77:1895-1899.

Shoda, T; Collins, MH; Rochman, M; Wen, T; Caldwell, JM; Mack, LE; Osswald, GA; Besse, JA; Haberman, Y; Aceves, SS; Mingler, M; Minnicozzi, M; Muir, A; Murray-Petzold, C. Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study. Gastroenterology. 2022; 162:1635-1649.

Hirano, I; Collins, MH; King, E; Sun, Q; Chehade, M; Abonia, JP; Bonis, PA; Capocelli, KE; Dellon, ES; Falk, GW; Yang, GY; Rothenberg, ME; Aceves, SS; Furuta, GT. Prospective Endoscopic Activity Assessment for Eosinophilic Gastritis in a Multisite Cohort. The American Journal of Gastroenterology (Elsevier). 2022; 117:413-423.

Min, S; Shoda, T; Wen, T; Rothenberg, ME. Diagnostic merits of the Eosinophilic Esophagitis Diagnostic Panel from a single esophageal biopsy. Journal of Allergy and Clinical Immunology. 2022; 149:782-787.e1.

Shoda, T; Wen, T; Caldwell, JM; Ben-Baruch Morgenstern, N; Osswald, GA; Rochman, M; Mack, LE; Felton, JM; Abonia, JP; Arva, NC; Mingler, M; Minnicozzi, M; Muir, A; MurrayPetzold, C. Loss of Endothelial TSPAN12 Promotes Fibrostenotic Eosinophilic Esophagitis via Endothelial Cell-Fibroblast Crosstalk. Gastroenterology. 2022; 162:439-453.

Shoda, T; Kaufman, KM; Wen, T; Caldwell, JM; Osswald, GA; Purnima, P; Zimmermann, N; Collins, MH; Rehn, K; Foote, H; Mukkada, VA; Putnam, PE; Martin, LJ; Rothenberg, ME. Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis. Nature Communications. 2021; 12:6795.

Chiang, AW T; Duong, LD; Shoda, T; Nhu, QM; Ruffner, M; Hara, T; Aaron, B; Joplin, E; Manresa, MC; Abonia, JP; Rothenberg, ME; Lewis, NE; Muir, AB; Aceves, SS. Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders. Journal of Pediatric Gastroenterology and Nutrition. 2021; 72:718-722.

Lyles, JL; Martin, LJ; Shoda, T; Collins, MH; Trimarchi, MP; He, H; Kottyan, LC; Mukkada, VA; Rothenberg, ME. Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants. Journal of Allergy and Clinical Immunology. 2021; 147:244-254.e6.

O'Shea, KM; Rochman, M; Shoda, T; Zimmermann, N; Caldwell, J; Rothenberg, ME. Eosinophilic esophagitis with extremely high esophageal eosinophil counts. Journal of Allergy and Clinical Immunology. 2021; 147:409-412.e5.

Emi-Sugie, M; Shoda, T; Futamura, K; Takeda, T; Ainai, A; Hasegawa, H; Saito, H; Matsumoto, K; Matsuda, A. Robust production of IL-33 and TSLP by lung endothelial cells in response to low-dose dsRNA stimulation. Journal of Allergy and Clinical Immunology. 2020; 146:1449-1452.e2.

Yang, L; Yamamoto-Hanada, K; Ishitsuka, K; Ayabe, T; Mezawa, H; Konishi, M; Shoda, T; Sago, H; Saito, H; Ohya, Y; Hirooka, Y; Suganuma, N; Kusuhara, K; Katoh, T. Medical and surgical complications in pregnancy and obstetric labour complications in the Japan Environment and Children's Study (JECS) cohort: a birth cohort study. Journal of Obstetrics and Gynaecology. 2020; 40:918-924.

Dunn, JL M; Shoda, T; Caldwell, JM; Wen, T; Aceves, SS; Collins, MH; Dellon, ES; Falk, GW; Leung, J; Martin, LJ; Yang, G; Furuta, GT; Rothenberg, ME; Gastrointe, CE. Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort. Journal of Allergy and Clinical Immunology. 2020; 145:1629-1640.e4.

Shoda, T; Wen, T; Caldwell, JM; Collins, MH; Besse, JA; Osswald, GA; Abonia, JP; Arva, NC; MDd, DA; Capocelli, KE; Aceves, SS; Furuta, GT; Rothenberg, ME; Gastrointe, CE. Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study. Journal of Allergy and Clinical Immunology. 2020; 145:255-269.