2021 Research Annual Report
By the Numbers

Internal Funding

Center for Clinical and Translational Science and Training (CCTST) Program Awards

Cincinnati Children’s partners with the University of Cincinnati and other institutions to support programs funded through the Center for Clinical and Translational Science and Training (CCTST). This list shows faculty who received grants to support translational research, build core capabilities, develop innovative research methods, or collaborate with community partners.

PI PI Division Co-I Co-I Division Title
June Goto Nakamura, PhD Neurosurgery Francesco Mangano,DO, FACS, FAAP, FACOS Neurosurgery Targeted gene therapy for the prevention and treatment of X-linked hydrocephalus
Hee Kim, MD Radiology Cuixia Tian, MD Neurology Imaging biomarker of acute muscle damage in Duchenne muscular dystrophy (DMD)
Theodosia Kalfa, MD, PhD Hematology Mary Risinger, PhD
Charles Quinn, MD, MS
College of Nursing
Hematology
Targeted Treatment in Sickle Cell Disease
Nicholas Ollberding, PhD Biostatistics and Epidemiology David Haslam, MD
Michael Wagner, PhD
Mekibib Altaye, PhD
Infectious Disease
Biomedical Informatics
Biostatistics and Epidemiology
Microbial Metagenomics Analysis Core
Nicolas Nassar, PhD Pharmacological Inhibition of Vav3 in TKI-Resistant Ph+ B-ALL
Yan Xu, PhD Pulmonary Biology Apply single cell ATAC-Seq to determine chromatin accessibility of LAM lung
Emily Miraldi, PhD Immunobiology and Biomedical Informatics Stephen Waggoner, PhD CAGE Engineering innate lymphoid cells in health and disease
Elaine Urbina, MD, MS Cardiology Lisa Martin, PhD Human Genetics Epigenetics, Diet & Vascular Dysfunction in T1DM
Md Nasimuzzaman, PhD Experimental Hematology and Cancer Biology Generation of a PAR-4flox/flox Mouse
Gang Huang Pharmaceutical Sciences Exploring the Metabolic Reprogramming in Leukemic Transformation in Mouse Models
Vivian Hwa, PhD Endocrinology Insulin-induced Enhancer RNA Regulation of IGF1 Expression in Patient-based iPSC models
Daniel Prows, PhD Human Genetics Nives Zimmermann, MD Pediatrics Cardiac imaging the mutant mouse line: eosinophilic myocarditis to heart disease
H. Leighton "Lee" Grimes, PhD Pediatrics/Immunobiology Gut microbiome regulation of hematopoietic progenitor biology
Rana Herro, PhD Pediatrics/Immunobiology Shedding LIGHT and TL1A on Neutrophilic Asthma
Ian Lewkowich, PhD Pediatrics/Immunobiology Phosphoproteomic characterization of IL-13 signaling
Bin Huang, PhD Biostatistics and Epidemiology Michal Kouril, PhD Biomedical Informatics 2nd year funding- Advance Casual Inference Methods for Data-powered Health
Xueheng Zhao Pathology Liang Niu Bioinformatics and Biostatistics Developing machine learning method for longitudinal metabolomics data analysis
Rick Ittenbach, PhD Biostatistics and Epidemiology Jeremy Corsmo Research Compliance uConsent: Participant Understanding in Clinical Research
Sang Hoon Lee, MD, MEd Emergency Medicine Gary Geis, MD Emergency Medicine Evaluating Remote Training and Assessment via Video
Mina Busch Single IRB Presentation
Tanya Froehlich, MD, MS, and Nichole Nidey, MS, PhD Professor of Pediatrics & Research Fellow, Epi/Pediatrics, CCHMC Pam Born, Donna Collier-Strepp, and Susan Ford + Patient Partners OhioHealth Physician Group, Adena Baby-Centered Recovery, Ohio Perinatal Quality Collaborative
Laura Olexa, RN, BSN, and Linda Helms Veggies via Vespa/North Fairmount Community Center Lisa Vaughn, PhD, and Stacey Gomes, MS
Dena Cranley, MA, and Barbara Lynch Chairs, First Ladies for Health Monica Mitchell, PhD

Children’s Health Research Career Development Award (CHRCDA)

This NICHD-funded program provides grants to support training physician-scientists to stimulate pediatric research across a variety of disciplines. This year’s awardees are:

Name Division Title of Research
Sonya Tang Girdwood, MD Hospital Medicine Optimizing Piperacillin Therapy in Pediatric Patients
Anna Peters, MD, PhD Gastroenterology, Hepatology and Nutrition Transcriptional Characterization of Pathogenic B Cells in Pediatric Liver Transplant Rejection
Meredith Schuh, MD Nephrology and Hypertension Molecular Analysis of Third Trimester Renal Progenitor Cells in the Primate Model

Fifth Third Bank/Charlotte R. Schmidlapp Women Scholars Awards

This program provides grants to support the academic career development of women faculty who have demonstrated academic potential and leadership skills as they progress toward the ranks of associate and full professor. This year’s awardees are:

Name Division Year
Elisa Boscolo, PhD Experimental Hematology and Cancer Biology 2020-2021
Megan McGrady, PhD Behavioral Medicine and Clinical Psychology 2021-2022

Place Outcome Awards

This program, administered by the James M. Anderson Center for Health Systems Excellence, provides grants to stimulate the development of health services and quality improvement research at Cincinnati Children’s and to ensure optimal implementation of clinical and operational innovations in the care delivery system. Awardees receiving funding are:

PI Name Division Award Title
Robert Ammerman, PhD, ABPP Behavioral Medicine and Clinical Psychology Integrated Behavioral Health Prevention in Pediatric Primary Care Improving Self-Regulation and Outcomes for Infants and Parents
Meera Kotagal, MD, MPH Pediatric General and Thoracic Surgery Co-designing and evaluating neighborhood-based interventions to reduce pediatric injury
Vanessa Olbrecht, MD, MBA Anesthesia Feasibility and acceptability of a biofeedback-based virtual reality intervention to manage postoperative pain in children and adolescents after surgery
Matthew Zackoff, MD, MEd Critical Care Medicine Interprofessional VR Training to Impact Recognition and Management of Sepsis
Roger Cornwall, MD Orthopaedic Surgery Lived Experience of Adults with Brachial Plexus Birth Injury (LEAP)

Procter Scholar Grant

The Procter Scholar Program supports faculty members from the Departments of Pediatrics, Surgery, Radiology, Patient Services, and Anesthesia who are committed to pursuing academic research careers.

PI Division Grant Title
David Smith, MD, PhD Pediatric Otolaryngology, Pulmonary Medicine Circadian clock dysregulation in a model of obstructive sleep apnea
William Zacharias, MD, PhD Pulmonary Biology Combined activity of the PRC2 and BAF complexes define the regenerative capacity of alveolar progenitors
Neha Santucci, MD Gastroenterology A comprehensive investigation of the role of sleep in adolescents with functional abdominal pain disorders
Maria Barnes-Davis, MD, PhD Neonatology and Pulmonary Biology Towards biomarkers of resiliency in the extremely preterm child: a multimodal neuroimaging study of brain and environment

Trustee Grant Awards

This program provides research funds for junior faculty to support rapid achievement of independent, sustained extramural funding for their research. This year’s awardees are:

PI Division Grant Title
Ziyuan Guo, PhD Developmental Biology Dopaminergic dysregulation in human in vitro circuit models of schizophrenia
Tamara Tilburgs, PhD Immunobiology Regulation of fetus and virus specific CD8+ T cell responses in human pregnancy
Rana Herro, PhD Immunobiology The combinatorial targeting of LIGHT and TL1A to treat Pulmonary Fibrosis
Jason Tchieu, PhD Developmental Biology Investigating the role of nuclear factor I (NFI) genes in modulating cortical neuron timing
John Robinson, MD, PhD Experimental Hematology and Cancer Biology Dissecting a superior colliculus output circuit for visual processing phenotypes in NF1
Mingxia Gu MD, PhD Pulmonary Biology Transcriptional and Epigenetic Basis of the Endothelial Defect in BPD-PH
Mattia Quattrocelli, PhD Molecular Cardiovascular Biology Pharmacological Mechanisms Enhancing Adiponectin Sensitivity in Dietary Obesity