2020 Research Annual Report
Research Annual Report | By the Numbers

Internal Funding

Center for Clinical and Translational Science and Training (CCTST) Program Awards

Cincinnati Children’s partners with the University of Cincinnati and other institutions to support programs funded through the Center for Clinical and Translational Science and Training (CCTST). This list shows faculty who received grants to support translational research, build core capabilities, develop innovative research methods, or collaborate with community partners.

Title PI PI Division Co-I Co-I Division
Olfactomedin 4 Marks a Unique Subset of Neutrophils Matthew Alder, MD, PhD Critical Care
"Using tears for biomarker discovery in children with juvenile idiopathic arthritis-associated uveitis" Sheila Angeles-Han, MD, MSc Rheumatology
Manipulating a Rho GTPase for cancer immunotherapy modulation Fukun Guo, PhD Experimental Hematology and Cancer Biology
Genetically-encoded nuclear imaging of genome edited cells Kotagiri Nalinikanth, MD, PhD Pharmacy Hu Yueh-Chiang, PhD Developmental Biology
Molecular Insights into Patient-Derived MED1 Mutant in Breast Cancer Therapy Resistance Xiaoting Zhang, PhD Cancer Biology
A nanoparticle-based vaccine against influenza virus Ming Tan, PhD Infectious Diseases Xi Jiang, PhD Infectious Diseases
Pharmacological Inhibition of Vav3 in TKI-Resistant Ph+ B-ALL Nicolas Nassar, PhD Cancer and Blood Diseases Institute Jose Cancelas MD, PhD Experimental Hematology and Cancer Biology
Investigating the role of exosomes as therapeutic targets/biomarkers for NASH Takahisa Nakamura, PhD Endocrinology Takanori Takebe, MD Gastroenterology, Hepatology and Nutrition
FMR1 Gene Therapy for Fragile X Syndrome Christina Gross, PhD Neurology Ernest Pedapati MD, MS Psychiatry and Neurology
Secreted phosphor-Hsp70 is a biomarker and therapeutic target in brain metastases Xiaoyang Qi, PhD Hematology and Oncology
From Electronic Health Records to Research Quality Data Eric Hall, PhD Biomedical Informatics
Teen substance use in the electronic medical record Sarah Beal, PhD Behavioral Medicine and Clinical Psychology
Advance Casual Inference Methods for Data-powered Health Bin Huang, PhD Biostatistics and Epidemiology
Developing an Informatics Solution to Collect EHR for Clinical Research Tzu-Yu (Danny) Wu, PhD, MSI Biomedical Informatics Brett Kissela, MD, MS Neurology
"Harnessing Purchasing Data for Dietary Interventions and Health Outcome Measures" Dylan Steen, MD, MS Cardiovascular Health and Disease Sarah Couch, PhD Nutritional Sciences
Fuzzy Bolt AI to Predict Recovery from PTSD After 12 Weeks of Therapy David Fleck, PhD, MA, BA Psychiatry and Behavioral Neuroscience Kelly Cohen, PhD Aerospace Engineering
Improving cohort identification and IRB chart review protocol process for research Brett Harnett, MS Biomedical Informatics
Predicting Patient Outcomes using Advances in Smartphone Sensing Todd Kelley, MD Orthopedic Surgery
Predicting Individual SES for Improved EHR research Cole Brokamp, PhD Biostatistics and Epidemiology
Use of Design and Innovation to Prevent Cardiac Arrest in Critically Ill Children Maya Dewan, MD, MPH Critical Care
Reducing Barriers to Early Intervention for At-Risk Preschoolers Karen Burkett, PhD Patient Services - Nursing
Developing Sustainable Arts & Music Programs in Carthage & Roselawn Carthage Christian Church
The Cincinnati Asthma Friendly Environments Partnership (CAFE) People Working Cooperatively
A Needs Assessment of African American Women Living in Poverty Community Engagement Collective

Children’s Health Research Career Development Award (CHRCDA)

This NICHD-funded program provides grants to support training physician-scientists to stimulate pediatric research across a variety of disciplines. This year’s awardees are:

Name Division Title of Research
Michael Sherenian, MD, MS Asthma Research Hemostasis in Atopic Dermatitis
Anna Peters, MD, PhD Gastroenterology, Hepatology and Nutrition Transcriptional characterization of pathogenic B cells in pediatric liver transplant rejection
Meredith Schuh, MD Nephrology and Hypertension Molecular Analysis of Third Trimester Renal Progenitor Cells in the Primate Model

Fifth Third Bank/Charlotte R. Schmidlapp Women Scholars Awards

This program provides grants to support the academic career development of women faculty who have demonstrated academic potential and leadership skills as they progress toward the ranks of associate and full professor. This year’s awardees are:

Name Division Year
Vidya Chidambaran, MD Anesthesia 2019-2020
Elisa Boscolo, PhD Experimental Hematology and Cancer Biology 2020-2021

Place Outcome Awards

This program, administered by the James M. Anderson Center for Health Systems Excellence, provides grants to stimulate the development of health services and quality improvement research at Cincinnati Children’s and to ensure optimal implementation of clinical and operational innovations in the care delivery system. Awardees receiving funding are:

PI Name Division Co PI Name Award Title
Meera Kotagal, MD, MPH General and Community Pediatrics Richard Falcone, MD, MPH; Andrew Beck, MD, MPH; Cole Brokamp, PhD Using place-based indicators to identify potential targets for injury prevention
Patrick Brady, MD, MSc Hospital Medicine and Anderson Center Katherine Auger, MD, MSc; Barbara Giambra, PhD, RN, CPNP; Samir Shah, MD, MSCE; Lisa Loechtenfeldt Improving Hospital to Home Transitions for Children with Medical Complexity
Sarah Corathers, MD Endocrinology Patrick Brady, MD, MSc; Nancy Daraiseh, PhD; Amanda Sylvester, MSN, APRN, CNP Artificial Intelligence Decision Support to Enhance Care for Type 1 Diabetes
Mark Paterno, PT, PhD, MBA, SCS, ATC Sports Medicine Bin Huang, BS, MS, PhD Alternative Models of Care to Improve Outcome After ACL Reconstruction
Ellen Lipstein, MD, MPH Anderson Center Lisa Vaughn, PhD; Lee Ann Conrad, DO, MPH A Comprehensive Assessment of Transgender-Related Decision Support Needs

Procter Scholar Grant

The Procter Scholar Program supports faculty members from the Departments of Pediatrics, Surgery, Radiology, Patient Services, and Anesthesia who are committed to pursuing academic research careers.

PI Division Grant Title
Akihiro Asai, MD, PhD Gastroenterology Modeling inherited cholestasis with patient-specific mutations
Nathan Evanson, MD, PhD Anesthesia Indirect traumatic optic neuropathy in a murine model of traumatic brain injury
Elizabeth Kramer, MD, PhD Pulmonary Medicine TGFβ Enhances Airway Smooth Muscle Dysfunction in Cystic Fibrosis via P13K
Ravindra Arya, MD, DM Neurology Development and validation of methodology for pre-surgical language mapping with stereo-EEG
Nicole Weaver, MD Human Genetics Understanding allelic and phenotypic heterogeneity in POLR1A phenotypes
Daniel Swarr, MD Neonatology and Pulmonary Biology Chromatin State Dynamics in SOX9+ Lung Epithelial Progenitor Cells
Matthew Alder, MD, PhD Critical Care Mechanism for Olfactomedin 4 in shock
Francis Real, MD, Med General Pediatrics Promoting Resilience and Emotional Health through Virtual Education Training
Omar Niss, MD Cancer and Blood Diseases Institute/Hematology Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease

Trustee Grant Awards

This program provides research funds for junior faculty to support rapid achievement of independent, sustained extramural funding for their research. This year’s awardees are:

PI Division Grant Title
Paritha Arumugam, PhD Neonatology and Pulmonary Biology Macrophage engraftment/maintenance and the durability of PMT therapeutic efficacy
Yueh-Chiang Hu, PhD Developmental Biology Differentiation of primordial germ cells by the genital ridge via BMP signaling
Yizhao Ni, PhD Biomedical Informatics BRIDGE: A Brain Image-Descriptor Generation Model to assist brain tumor evaluation
Rachelle Ramsey, PhD Behavioral Medicine and Clinical Psychology Using technology-assisted stepped care intervention to improve adherence in adolescents with asthma
Lili He, PhD Neonatology and Pulmonary Biology Early Prediction of neurodevelopmental Deficits in Very Preterm Infants
Massashi Yamaji, PhD Reproductive Sciences Deciphering a micro environmental signaling network underlying proliferation and maintenance of spermatogonial stem/progenirot cells.
Marina Lopez-Sola, PhD Anesthesiology Discovering a nerual signature specific for juvenile fibromyalgia vs. juvenile idiopathic arthritis
Natoshia Cunningham, PhD Behavioral Medicine and Clinical Psychology Brain Mechanisms of Attention and Pain in Youth with Functional Abdominal Pain Disorders and Comorbid Anxiety
Alonzo Folger PhD, MS Epidemiology and Biostatistics Linking Adversity, DNA Methylation, and Early Development in Home Visiting PU
Makiko Iwafuchi-Doi, PhD Developmental Biology Elucidating the pioneering mechanisms of FOXA to establish open and heterochromatin domains during endodermal specifications
Yaping Lu, PhD Human Genetics Modeling cell-free DNA fragmentation patterns for genome-wide association study
Laura Walkup, PhD Pulmonary Medicine Regional lung ventilation-perfusion of pediatric CF via 129Xe gas-exchange MRI
Juan Sanchez Gurmaches, PhD Endocrinology Developmental Heterogeneity of Adipose Tissues
Hee Woong Lim, PhD Biomedical Informatics High-resolution mapping of protein-genome interactions using CUT & RUN
Kelli VanDussen, PhD Gastroenterology ILEAL Microvilli Phenotypes as zPredictors of Crohn's Disease Clinical outcome