Inge, TH; Courcoulas, AP; Jenkins, TM; Michalsky, MP; Brandt, ML; Xanthakos, SA; Dixon, JB; Harmon, CM; Chen, MK; Xie, C; Evans, ME; Helmrath, MA; Teen–LABS Consortium. Five-Year Outcomes of Gastric Bypass in Adolescents as Compared with Adults. The New England journal of medicine. 2019; 380(22):2136-2145.
Complimentary study to earlier reports demonstrating efficacy of Gastric bypass procedure - another major contribution to the field
Katzenstein, HM D; Langham, MR; Malogolowkin, MH; Krailo, MD; Towbin, AJ; McCarville, MB; Finegold, MJ; Ranganathan, S; Dunn, S; McGahren, ED; Tiao, GM; O'Neill, AF; Qayed, M; Furman, WL; Xia, C; Rodriguez-Galindo, C; Meyers, RL. Minimal adjuvant chemotherapy for children with hepatoblastoma resected at diagnosis AHEP0731 a Childrens Oncology Group, multicentre, phase 3 trial. The Lancet Oncology. 2019; 20(5):719-727.
First major report from AHEP 0731 trial demonstrating the efficacy of resection at diagnosis followed by treatment with low intensity chemotherapy
Nguyen, P; Valanejad, L; Cast, A; Wright, M; Garcia, JM; El-Serag, HB; Karns, R; Timchenko, NA. Elimination of Age-Associated Hepatic Steatosis and Correction of Aging Phenotype by Inhibition of cdk4-CEBP alpha-p300 Axis. Cell Reports. 2018; 24(6):1597-1609.
Important contribution focused on mechanistic basis of steatosis
Kotagal, M; Slusher, J; Ahmad, S; Aronson, LA; Brunner, J; Chima, R; Elder, DA; Goldschneider, KR; Hornung, L; Lin, TK; Ogg, SM; Palermo, JJ; Rich, K; Rose, J; Sekoulopoulos, T; Szabova, A; Abu-El-Haija, M; Nathan, JD. In-hospital and 90-day outcomes after total pancreatectomy with islet autotransplantation for pediatric chronic and acute recurrent pancreatitis. American Journal of Transplantation. 2019; 19(4):1187-1194.
First report from CCHMC TPIAT program demonstrating efficacy of procedure
Oria, M; Figueira, RL; Scorletti, F; Sbragia, L; Owens, K; Li, Z; Pathak, B; Corona, MU; Marotta, M; Encinas, JL; Peiro, JL. CD200-CD200R imbalance correlates with microglia and pro-inflammatory activation in rat spinal cords exposed to amniotic fluid in retinoic acid-induced spina bifida. Scientific Reports. 2018; 8(1).
Mechanistic study on the basis of inflammatory factors that impact pathophysiology of MMC