Division Publications
Abruzzo TA, Geller JI, Kimbrough DA, Michaels S, Correa ZM, Cornell K, Augsburger JJ. Adjunctive Techniques for Optimization of Ocular Hemodynamics in Children Undergoing Ophthalmic Artery Infusion Chemotherapy. J Neurointerv Surg . 2015; 7:770-6.
Adams A, Bolanos L, Dexheimer P, Karns R, Aronow B, Komurov K, Jegga A, Casper K, Patil Y, Wilson K. Irak1 Is a Novel Dek Transcriptional Target and Is Essential for Head and Neck Cancer Cell Survival. Oncotarget . 2015; 6:43395-407.
Adams DM, Trenor CC, 3rd, Hammill AM, Vinks AA, Patel MN, Chaudry G, Wentzel MS, Mobberley-Schuman PS, Campbell LM, Brookbank C, Gupta A, Chute C, Eile J, McKenna J, Merrow AC, Fei L, Hornung L, Seid M, Dasgupta AR, Dickie BH, et al. Efficacy and Safety of Sirolimus in the Treatment of Complicated Vascular Anomalies. Pediatrics . 2016; 137:e20153257.
Alsaied T, Mohameden M, Lee L, Lawson S, Mantell B, Saqr A, Nagarajan R. Abdominal Pain, Fatigue, and Constipation in a Teenager Female: Is It Worth Further Investigations? Clinc Pediatr (Phila) . 2016; 55:986-9.
Anderson CP, Matthay KK, Perentesis JP, Neglia JP, Bailey HH, Villablanca JG, Groshen S, Hasenauer B, Maris JM, Seeger RC, Reynolds CP. Pilot Study of Intravenous Melphalan Combined with Continuous Infusion L-S,R-Buthionine Sulfoximine for Children with Recurrent Neuroblastoma. Pediatr Blood Cancer . 2015; 62:1739-46.
Bielack SS, Smeland S, Whelan JS, Marina N, Jovic G, Hook JM, Krailo MD, Gebhardt M, Papai Z, Meyer J, Nadel H, Randall RL, Deffenbaugh C, Nagarajan R, Brennan B, Letson GD, Teot LA, Goorin A, Baumhoer D, Kager L, et al. Methotrexate, Doxorubicin, and Cisplatin (Map) Plus Maintenance Pegylated Interferon Alfa-2b Versus Map Alone in Patients with Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative Map: First Results of the Euramos-1 Good Response Randomized Controlled Trial. J Clin Oncol . 2015; 33:2279-87.
Breese E, Buechele C, Dawson C, Cleary M, Porteus M. Use of Genome Engineering to Create Patient Specific Mll Translocations in Primary Human Hematopoietic Stem and Progenitor Cells. Plos One . 2015; 10:e0136644.
Buechele C, Breese EH, Schneidawind D, Lin CH, Jeong J, Duque-Afonso J, Wong SH, Smith KS, Negrin RS, Porteus M, Cleary ML. Mll Leukemia Induction by Genome Editing of Human Cd34+ Hematopoietic Cells. Blood . 2015; 126:1683-94.
Bukowinski AJ, Burns KC, Parsons K, Perentesis JP, O'Brien MM. Toxicity of Cancer Therapy in Adolescents and Young Adults (Ayas). Semin Oncol Nurs . 2015; 31:216-26.
Cajaiba M, Jennings L, Rohan S, Perez-Atayde A, Marino-Enriquez A, Fletcher J, Geller J, Leuer K, Bridge J, Perlman E. Alk-Rearranged Renal Cell Carcinomas in Children. Gene Chromosome Canc . 2016; 55:442-51.
Cajaiba MM, Jennings LJ, Rohan SM, Leuer KM, Anagnost MR, Fahner JB, Fulton BK, Geller JI, Perlman EJ. Expanding the Spectrum of Renal Tumors in Children: Primary Renal Myoepithelial Carcinomas with a Novel Ewsr1-Klf15 Fusion. Am J Surg Pathol . 2016; 40:386-94.
Cajaiba MM, Khanna G, Smith EA, Gellert L, Chi YY, Mullen EA, Hill DA, Geller JI, Dome JS, Perlman EJ. Pediatric Cystic Nephromas: Distinctive Features and Frequent Dicer1 Mutations. Hum Pathol . 2016; 48:81-7.
Chlon TM, Ruiz-Torres S, Maag L, Mayhew CN, Wikenheiser-Brokamp KA, Davies SM, Mehta P, Myers KC, Wells JM, Wells SI. Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage. Stem Cell Reports . 2016; 6:44-54.
Conry RM, Rodriguez MG, Pressey JG. Zoledronic Acid in Metastatic Osteosarcoma: Encouraging Progression Free Survival in Four Consecutive Patients. Clin Sarcoma Res . 2016; 6:6.
Cramer SL, Wei S, Merrow AC, Pressey JG. Gorham-Stout Disease Successfully Treated with Sirolimus and Zoledronic Acid Therapy. J Pediatr Hematol Oncol . 2016; 38:e129-32.
Dahl NA, Michaels ST, McMasters RL, Chandra S, O'Brien MM. Azacitidine and Sorafenib Therapy in a Pediatric Patient with Refractory Acute Myeloid Leukemia with Monosomy 7 and Somatic Ptpn11 Mutation. Pediatr Blood Cancer . 2016; 63:551-3.
Dandoy CE, Hariharan S, Weiss B, Demmel K, Timm N, Chiarenzelli J, Dewald MK, Kennebeck S, Langworthy S, Pomales J, Rineair S, Sandfoss E, Volz-Noe P, Nagarajan R, Alessandrini E. Sustained Reductions in Time to Antibiotic Delivery in Febrile Immunocompromised Children: Results of a Quality Improvement Collaborative. BMJ Qual Saf . 2016; 25:100-9.
Dasgupta B, Chhipa RR. Evolving Lessons on the Complex Role of Ampk in Normal Physiology and Cancer. Trends Pharmacol Sci . 2016; 37:192-206.
Davis J, Kreppel A, Brady R, Jones B, Stevenson C, Fouladi M, Hummel T. Nocardia Farcinica Meningitis Masquerading as Central Nervous System Metastasis in a Child with Cerebellar Pilocytic Astrocytoma. J Pediatr Hematol Oncol . 2015; 37:482-85.
Dome J, Graf N, Geller J, Fernandez C, Mullen E, Spreafico F, Van den H-E, M, Pritchard-Jones K. Advances in Wilms Tumor Treatment and Biology: Progress through International Collaboration. J Clin Oncol . 2015; 33:2999-U94.
Ehrlich PF, Hamilton TE, Gow K, Barnhart D, Ferrer F, Kandel J, Glick R, Dasgupta R, Naranjo A, He Y, Perlman EJ, Kalapurakal JA, Khanna G, Dome JS, Geller J, Mullen E. Surgical Protocol Violations in Children with Renal Tumors Provides an Opportunity to Improve Pediatric Cancer Care: A Report from the Children's Oncology Group. Pediatr Blood Cancer . 2016; 63:1905-10.
Geller JI. Current Standards of Care and Future Directions for "High-Risk" Pediatric Renal Tumors: Anaplastic Wilms Tumor and Rhabdoid Tumor. Urol Oncol . 2016; 34:50-6.
Geller JI, Ehrlich PF, Cost NG, Khanna G, Mullen EA, Gratias EJ, Naranjo A, Dome JS, Perlman EJ. Characterization of Adolescent and Pediatric Renal Cell Carcinoma: A Report from the Children's Oncology Group Study Aren03b2. Cancer . 2015; 121:2457-64.
Glait-Santar C, Desmond R, Feng X, Bat T, Chen J, Heuston E, Mizukawa B, Mulloy J, Bodine D, Larochelle A. Functional Niche Competition between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells. Stem Cells . 2015; 33:3635-42.
Hoffman L, DeWire M, Ryall S, Buczkowicz P, Leach J, Miles L, Ramani A, Brudno M, Kumar S, Drissi R. Spatial Genomic Heterogeneity in Diffuse Intrinsic Pontine and Midline High-Grade Glioma: Implications for Diagnostic Biopsy and Targeted Therapeutics. pmc/PMC4700584. Acta Neuropathol Commun . 2016; 4:1.
Hoffman LM, Fouladi M, Olson J, Daryani VM, Stewart CF, Wetmore C, Kocak M, Onar-Thomas A, Wagner L, Gururangan S, Packer RJ, Blaney SM, Gajjar A, Kun LE, Boyett JM, Gilbertson RJ. Phase I Trial of Weekly Mk-0752 in Children with Refractory Central Nervous System Malignancies: A Pediatric Brain Tumor Consortium Study. Childs Nerv Syst . 2015; 31:1283-9.
Hummel TR, Salloum R, Drissi R, Kumar S, Sobo M, Goldman S, Pai A, Leach J, Lane A, Pruitt D, Sutton M, Chow LM, Grimme L, Doughman R, Backus L, Miles L, Stevenson C, Fouladi M, DeWire M. A Pilot Study of Bevacizumab-Based Therapy in Patients with Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas. J Neurooncol . 2016; 127:53-61.
Jones BV, Linscott L, Koberlein G, Hummel TR, Leach JL. Increased Prevalence of Developmental Venous Anomalies in Children with Intracranial Neoplasms. AJNR Am J Neuroradiol . 2015; 36:1782-5.
Kieran MW, Chi S, Goldman S, Onar-Thomas A, Poussaint TY, Vajapeyam S, Fahey F, Wu S, Turner DC, Stewart CF, Moses M, Packer RJ, Jakacki R, Banerjee A, Boyett JM, Fouladi M, Kun L. A Phase I Trial and Pk Study of Cediranib (Azd2171), an Orally Bioavailable Pan-Vegfr Inhibitor, in Children with Recurrent or Refractory Primary Cns Tumors. Childs Nerv Syst . 2015; 31:1433-45.
Kim MO, Wang X, Liu C, Dorris K, Fouladi M, Song S. Random-Effects Meta-Analysis for Systematic Reviews of Phase I Clinical Trials: Rare Events and Missing Data. Res Synth Methods . 2016.
Kim S-H, Ezhilarasan R, Phillips E, Gallego-Perez D, Sparks A, Taylor D, Ladner K, Furuta T, Sabit H, Chhipa R. Serine/Threonine Kinase Mlk4 Determines Mesenchymal Identity in Glioma Stem Cells in an Nf-Kappa B-Dependent Manner. Cancer Cell . 2016; 29:201-13.
Klionsky D, Abdelmohsen K, Abe A, Abedin M, Abeliovich H, Arozena A, Adachi H, Adams C, Adams P, Adeli Kea. Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (3rd Edition). Autophagy . 2016; 12:1-222.
Lu F, Chen Y, Zhao C, Wang H, He D, Xu L, Wang J, He X, Deng Y, Lu EE, Liu X, Verma R, Bu H, Drissi R, Fouladi M, Stemmer-Rachamimov AO, Burns D, Xin M, Rubin JB, Bahassi el M, et al. Olig2-Dependent Reciprocal Shift in Pdgf and Egf Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma. Cancer Cell . 2016; 29:669-83.
Lulla RR, Goldman S, Yamada T, Beattie CW, Bressler L, Pacini M, Pollack IF, Fisher PG, Packer RJ, Dunkel IJ, Dhall G, Wu S, Onar A, Boyett JM, Fouladi M. Phase I Trial of P28 (Nsc745104), a Non-Hdm2-Mediated Peptide Inhibitor of P53 Ubiquitination in Pediatric Patients with Recurrent or Progressive Central Nervous System Tumors: A Pediatric Brain Tumor Consortium Study. Neuro Oncol . 2016; 18:1319-25.
Matrka MC, Hennigan RF, Kappes F, DeLay ML, Lambert PF, Aronow BJ, Wells SI. Dek over-Expression Promotes Mitotic Defects and Micronucleus Formation. Cell Cycle . 2015; 14:3939-53.
McCarthy CE, O'Brien M, Andrews J, Zoland JM, Macasiray E, Wong W, Lo C, Glader B, Tamaresis J, Jeng M. Updated Analysis: Central Venous Access Device Infection Rates in an Expanded Cohort of Paediatric Patients with Severe Haemophilia Receiving Prophylactic Recombinant Tissue Plasminogen Activator. Haemophilia . 2016; 22:81-6.
Michaels ST, Abruzzo TA, Augsburger JJ, Correa ZM, Lane A, Geller JI. Selective Ophthalmic Artery Infusion Chemotherapy for Advanced Intraocular Retinoblastoma: Cchmc Early Experience. J Pediatr Hematol Oncol . 2016; 38:65-9.
Patel A, Johansson G, Colbert M, Dasgupta B, Ratner N. Fatty Acid Synthase Is a Metabolic Oncogene Targetable in Malignant Peripheral Nerve Sheath Tumors. Neuro Oncol . 2015; 17:1599-608.
Poussaint TY, Vajapeyam S, Ricci KI, Panigrahy A, Kocak M, Kun LE, Boyett JM, Pollack IF, Fouladi M. Apparent Diffusion Coefficient Histogram Metrics Correlate with Survival in Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium. Neuro Oncol . 2016; 18:725-34.
Prada C, Hufnagel R, Hummel T, Lovell A, Hopkin R, Saal H, Schorry E. The Use of Magnetic Resonance Imaging Screening for Optic Pathway Gliomas in Children with Neurofibromatosis Type 1. J Pediatr 2015; 167:851.
Rao R, Salloum R, Xin M, Lu Q. The G Protein G Alpha(S) Acts as a Tumor Suppressor in Sonic Hedgehog Signaling-Driven Tumorigenesis. Cell Cycle . 2016; 15:1325-30.
Rayes A, McMasters RL, O'Brien MM. Lineage Switch in Mll-Rearranged Infant Leukemia Following Cd19-Directed Therapy. Pediatr Blood Cancer . 2016; 63:1113-5.
Robinson GW, Orr BA, Wu G, Gururangan S, Lin T, Qaddoumi I, Packer RJ, Goldman S, Prados MD, Desjardins A, Chintagumpala M, Takebe N, Kaste SC, Rusch M, Allen SJ, Onar-Thomas A, Stewart CF, Fouladi M, Boyett JM, Gilbertson RJ, et al. Vismodegib Exerts Targeted Efficacy against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results from Phase Ii Pediatric Brain Tumor Consortium Studies Pbtc-025b and Pbtc-032. J Clin Oncol . 2015; 33:2646-54.
Romick-Rosendale L, Hoskins E, Vinnedge L, Foglesong G, Brusadelli M, Potter S, Komurov K, Brugmann S, Lambert P, Kimple R. Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-Pk and Rac1 Signaling. Clin Cancer Res . 2016; 22:2062-73.
Rutter MM, Jha P, Schultz KA, Sheil A, Harris AK, Bauer AJ, Field AL, Geller J, Hill DA. Dicer1 Mutations and Differentiated Thyroid Carcinoma: Evidence of a Direct Association. J Clin Endocrinol Metab . 2016; 101:1-5.
Salloum R, Fox CE, Alvarez-Allende CR, Hammill AM, Dasgupta R, Dickie BH, Mobberley-Schuman P, Wentzel MS, Chute C, Kaul A, Patel M, Merrow AC, Gupta A, Whitworth JR, Adams DM. Response of Blue Rubber Bleb Nevus Syndrome to Sirolimus Treatment. Pediatr Blood Cancer . 2016; 63:1911-4.
Salloum R, Hummel TR, Kumar SS, Dorris K, Li S, Lin T, Daryani VM, Stewart CF, Miles L, Poussaint TY, Stevenson C, Goldman S, Dhall G, Packer R, Fisher P, Pollack IF, Fouladi M, Boyett J, Drissi R. A Molecular Biology and Phase Ii Study of Imetelstat (Grn163l) in Children with Recurrent or Refractory Central Nervous System Malignancies: A Pediatric Brain Tumor Consortium Study. J Neurooncol . 2016; 129:443-51.
Sharp SE, Trout AT, Weiss BD, Gelfand MJ. Mibg in Neuroblastoma Diagnostic Imaging and Therapy. Radiographics . 2016; 36:258-78.
Shi Y, Geller JI, Ma IT, Chavan RS, Masand PM, Towbin AJ, Chintagumpala M, Nuchtern JG, Tiao GM, Thompson PA, Vasudevan SA. Relapsed Hepatoblastoma Confined to the Lung Is Effectively Treated with Pulmonary Metastasectomy. J Pediatr Surg . 2016; 51:525-29.
Smith E, Matrka M, Wells S. Hpv Virology: Cellular Targets of Hpv Oncogenes and Transformation . In: D Miller, M Stack, eds. Human Papillomavirus (Hpv)-Associated Oropharyngeal Cancer . New York: Springer; 2015:69-101.
Steed TC, Treiber JM, Patel K, Ramakrishnan V, Merk A, Smith AR, Carter BS, Dale AM, Chow LM, Chen CC. Differential Localization of Glioblastoma Subtype: Implications on Glioblastoma Pathogenesis. Oncotarget . 2016; 7:24899-907.
Studebaker A, Bondra K, Seum S, Shen C, Phelps DA, Chronowski C, Leasure J, Smith PD, Kurmasheva RT, Mo X, Fouladi M, Houghton PJ. Inhibition of Mek Confers Hypersensitivity to X-Radiation in the Context of Braf Mutation in a Model of Childhood Astrocytoma. Pediatr Blood Cancer . 2015; 62:1768-74.
Sturm D, Orr BA, Toprak UH, Hovestadt V, Jones DT, Capper D, Sill M, Buchhalter I, Northcott PA, Leis I, Ryzhova M, Koelsche C, Pfaff E, Allen SJ, Balasubramanian G, Worst BC, Pajtler KW, Brabetz S, Johann PD, Sahm F, et al. New Brain Tumor Entities Emerge from Molecular Classification of Cns-Pnets. Cell . 2016; 164:1060-72.
Tiao G, Geller J, Timchenko N. Generation of Plc-Pdx Platforms for Pediatric Liver Cancer: A Critical Stage in the Development of Anti-Cancer Treatments. Hepatology . 2016; 64:1017-9.
Trout A, Sharp S, Turpin B, Zhang B, Gelfand M. Optimizing the Interval between G-Csf Therapy and F-18 Fdg Pet Imaging in Children and Young Adults Receiving Chemotherapy for Sarcoma. Pediatric Radiol . 2015; 45:1001-06.
Trout AT, Towbin AJ, Klingbeil L, Weiss BD, von Allmen D. Single and Multidimensional Measurements Underestimate Neuroblastoma Response to Therapy. Pediatr Blood Cancer . 2016.
Tuttle T, Mierzwa M, Wells S, Fox S, Ben-Jonathan N. The Cyclic Gmp/Protein Kinase G Pathway as a Therapeutic Target in Head and Neck Squamous Cell Carcinoma. Cancer Letters . 2016; 370:279-85.
Warren M, Turpin BK, Mark M, Smolarek TA, Li X. Undifferentiated Myxoid Lipoblastoma with Plag1-Has2 Fusion in an Infant; Morphologically Mimicking Primitive Myxoid Mesenchymal Tumor of Infancy (Pmmti)--Diagnostic Importance of Cytogenetic and Molecular Testing and Literature Review. Cancer Genet . 2016; 209:21-9.