Clinical Pharmacology
Publications
Division Publications
Adams DM, Trenor CC, 3rd, Hammill AM, Vinks AA, Patel MN, Chaudry G, Wentzel MS, Mobberley-Schuman PS, Campbell LM, Brookbank C, Gupta A, Chute C, Eile J, McKenna J, Merrow AC, Fei L, Hornung L, Seid M, Dasgupta AR, Dickie BH, et al. Efficacy and Safety of Sirolimus in the Treatment of Complicated Vascular Anomalies. Pediatrics . 2016; 137:e20153257.
Arya R, Gillespie CW, Cnaan A, Devarajan M, Clark P, Shinnar S, Vinks AA, Mizuno K, Glauser TA, Childhood Absence Epilepsy Study G. Obesity and Overweight as Cae Comorbidities and Differential Drug Response Modifiers. Neurology . 2016; 86:1613-21.
Birdwell KA, Decker B, Barbarino JM, Peterson JF, Stein CM, Sadee W, Wang D, Vinks AA, He Y, Swen JJ, Leeder JS, van Schaik R, Thummel KE, Klein TE, Caudle KE, MacPhee IA. Clinical Pharmacogenetics Implementation Consortium (Cpic) Guidelines for Cyp3a5 Genotype and Tacrolimus Dosing. Clin Pharmacol Ther . 2015; 98:19-24.
Brouwer KL, Aleksunes LM, Brandys B, Giacoia GP, Knipp G, Lukacova V, Meibohm B, Nigam SK, Rieder M, de Wildt SN, Pediatric Transporter Working Group. Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group. Clin Pharmacol Ther . 2015; 98:266-87.
Chidambaran V, Venkatasubramanian R, Sadhasivam S, Esslinger H, Cox S, Diepstraten J, Fukuda T, Inge T, Knibbe CA, Vinks AA. Population Pharmacokinetic-Pharmacodynamic Modeling and Dosing Simulation of Propofol Maintenance Anesthesia in Severely Obese Adolescents. Paediatr Anaesth . 2015; 25:911-23.
Chidambaran V, Venkatasubramanian R, Zhang X, Martin LJ, Niu J, Mizuno T, Fukuda T, Meller J, Vinks AA, Sadhasivam S. Abcc3 Genetic Variants Are Associated with Postoperative Morphine-Induced Respiratory Depression and Morphine Pharmacokinetics in Children. Pharmacogenomics J . 2016.
Christians U, Vinks AA, Langman LJ, Clarke W, Wallemacq P, van Gelder T, Renjen V, Marquet P, Meyer EJ. Impact of Laboratory Practices on Interlaboratory Variability in Therapeutic Drug Monitoring of Immunosuppressive Drugs. Ther Drug Monit . 2015; 37:718-24.
Dong M, McGann PT, Mizuno T, Ware RE, Vinks AA. Development of a Pharmacokinetic-Guided Dose Individualization Strategy for Hydroxyurea Treatment in Children with Sickle Cell Anaemia. Br J Clin Pharmacol . 2016; 81:742-52.
Downes K, Goldstein S, Vinks A. Increased Vancomycin Exposure and Nephrotoxicity in Children: Therapeutic Does Not Mean Safe. J Pediatr Infect Dis Soc . 2016; 5:65-67.
Emoto C, Fukuda T, Venkatasubramanian R, Vinks AA. The Impact of Cyp3a5*3 Polymorphism on Sirolimus Pharmacokinetics: Insights from Predictions with a Physiologically-Based Pharmacokinetic Model. Br J Clin Pharmacol . 2015; 80:1438-46.
Emoto C, Vinks AA, Fukuda T. Risk Assessment of Drug-Drug Interactions of Calcineurin Inhibitors Affecting Sirolimus Pharmacokinetics in Renal Transplant Patients. Ther Drug Monit . 2016; 38:607-13.
Gist KM, Goldstein SL, Joy MS, Vinks AA. Milrinone Dosing Issues in Critically Ill Children with Kidney Injury: A Review. J Cardiovasc Pharmacol . 2016; 67:175-81.
Gist KM, Mizuno T, Goldstein SL, Vinks A. Retrospective Evaluation of Milrinone Pharmacokinetics in Children with Kidney Injury. Ther Drug Monit . 2015; 37:792-6.
Hahn A, Frenck RW, Jr., Allen-Staat M, Zou Y, Vinks AA. Evaluation of Target Attainment of Vancomycin Area under the Curve in Children with Methicillin-Resistant Staphylococcus Aureus Bacteremia. Ther Drug Monit . 2015; 37:619-25.
Hahn A, Fukuda T, Hahn D, Mizuno T, Frenck RW, Jr., Vinks AA. Pharmacokinetics and Pharmacogenomics of Beta-Lactam-Induced Neutropenia. Pharmacogenomics . 2016; 17:547-59.
Hayashi S, Ohashi K, Mihara S, Nakata E, Emoto C, Ohta A. Discovery of Small-Molecule Nonpeptide Antagonists of Nociceptin/Orphanin Fq Receptor: The Studies of Design, Synthesis, and Structure-Activity Relationships for (4-Arylpiperidine Substituted-Methyl)-[Bicyclic (Hetero)Cycloalkanobenzene] Derivatives. Eur J Med Chem . 2016; 114:345-64.
Jodele S, Fukuda T, Mizuno K, Vinks AA, Laskin BL, Goebel J, Dixon BP, Chima RS, Hirsch R, Teusink A, Lazear D, Lane A, Myers KC, Dandoy CE, Davies SM. Variable Eculizumab Clearance Requires Pharmacodynamic Monitoring to Optimize Therapy for Thrombotic Microangiopathy after Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant . 2016; 22:307-15.
Nehus EJ, Mizuno T, Cox S, Goldstein SL, Vinks AA. Pharmacokinetics of Meropenem in Children Receiving Continuous Renal Replacement Therapy: Validation of Clinical Trial Simulations. J Clin Pharmacol . 2016; 56:291-7.
Ngamprasertwong P, Dong M, Niu J, Venkatasubramanian R, Vinks AA, Sadhasivam S. Propofol Pharmacokinetics and Estimation of Fetal Propofol Exposure During Mid-Gestational Fetal Surgery: A Maternal-Fetal Sheep Model. PLoS One . 2016; 11:e0146563.
Rohan JM, Fukuda T, Alderfer MA, Wetherington Donewar C, Ewing L, Katz ER, Muriel AC, Vinks AA, Drotar D. Measuring Medication Adherence in Pediatric Cancer: An Approach to Validation. J Pediatr Psychol . 2016.
Rosen MJ, Minar P, Vinks AA. Letter: Stool Adalimumab Detection in Ulcerative Colitis and Crohn's Disease--Authors' Reply. Aliment Pharmacol Ther . 2015; 42:241.
Shokati T, Bodenberger N, Gadpaille H, Schniedewind B, Vinks A, Jiang W, Alloway R, Christians U. Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using Lc-Ms/Ms. J Vis Exp . 2015; 8:e52424.
Teusink A, Vinks A, Zhang K, Davies S, Fukuda T, Lane A, Nortman S, Kissell D, Dell S, Filipovich A, Mehta P. Genotype-Directed Dosing Leads to Optimized Voriconazole Levels in Pediatric Patients Receiving Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant . 2016; 22:482-6.
Vinks A. Therapeutic Optimization as Part of the Precision Medicine Paradigm. Clin Pharmacol Ther . 2016; 99:340-42.
Vinks AA, Emoto C, Fukuda T. Modeling and Simulation in Pediatric Drug Therapy: Application of Pharmacometrics to Define the Right Dose for Children. Clin Pharmacol Ther . 2015; 98:298-308.
Wiles JR, Isemann B, Mizuno T, Tabangin ME, Ward LP, Akinbi H, Vinks AA. Pharmacokinetics of Oral Methadone in the Treatment of Neonatal Abstinence Syndrome: A Pilot Study. J Pediatr . 2015; 167:1214-20 e3.
Yang X, Sherwin CM, Yu T, Yellepeddi VK, Brunner HI, Vinks AA. Pharmacokinetic Modeling of Therapies for Systemic Lupus Erythematosus. Expert Rev Clin Pharmacol . 2015; 8:587-603.