2016 Research Annual Report

Publications

Publications

Publications with the Highest Impact Factor (Listed Highest to Lowest)

Burton BK, Balwani M, Feillet F, Baric I, Burrow TA, Camarena Grande C, Coker M, Consuelo-Sanchez A, Deegan P, Di Rocco M, Enns GM, Erbe R, Ezgu F, Ficicioglu C, Furuya KN, Kane J, Laukaitis C, Mengel E, Neilan EG, Nightingale S, et al. A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency. N Engl J Med. 2015; 373:1010-20.

Inge TH, Courcoulas AP, Jenkins TM, Michalsky MP, Helmrath MA, Brandt ML, Harmon CM, Zeller MH, Chen MK, Xanthakos SA, Horlick M, Buncher CR, Teen Labs Consortium. Weight Loss and Health Status 3 Years after Bariatric Surgery in Adolescents. N Engl J Med. 2016; 374:113-23.

Wainwright C, Elborn J, Ramsey B, Marigowda G, Huang X, Cipolli M, Colombo C, Davies J, De B, K, Flume P. Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del Cftr. N Eng J Med. 2015; 373:220-31.

Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, et al. Inherited Determinants of Crohn's Disease and Ulcerative Colitis Phenotypes: A Genetic Association Study. Lancet. 2016; 387:156-67.

Towbin JA, Lorts A, Jefferies JL. Left Ventricular Non-Compaction Cardiomyopathy. Lancet. 2015; 386:813-25.

Ware RE, Davis BR, Schultz WH, Brown RC, Aygun B, Sarnaik S, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone C, Lee MT, Kwiatkowski JL, Jackson S, Miller ST, Roberts C, et al. Hydroxycarbamide Versus Chronic Transfusion for Maintenance of Transcranial Doppler Flow Velocities in Children with Sickle Cell Anaemia-Tcd with Transfusions Changing to Hydroxyurea (Twitch): A Multicentre, Open-Label, Phase 3, Non-Inferiority Trial. Lancet. 2016; 387:661-70.

Alipanahi B, Delong A, Weirauch MT, Frey BJ. Predicting the Sequence Specificities of DNA- and Rna-Binding Proteins by Deep Learning. Nat Biotechnol. 2015; 33:831-8.

Pelossof R, Singh I, Yang JL, Weirauch MT, Hughes TR, Leslie CS. Affinity Regression Predicts the Recognition Code of Nucleic Acid-Binding Proteins. Nat Biotechnol. 2015; 33:1242-49.

Rosenblum MD, Way SS, Abbas AK. Regulatory T Cell Memory. Nat Rev Immunol. 2016; 16:90-101.

Ma H, Folmes CD, Wu J, Morey R, Mora-Castilla S, Ocampo A, Ma L, Poulton J, Wang X, Ahmed R, Kang E, Lee Y, Hayama T, Li Y, Van Dyken C, Gutierrez NM, Tippner-Hedges R, Koski A, Mitalipov N, Amato P, et al. Metabolic Rescue in Pluripotent Cells from Patients with Mtdna Disease. Nature. 2015; 524:234-8.

Babcock L, Kurowski B. Identifying Children and Adolescents at Risk for Persistent Postconcussion Symptoms. JAMA. 2016; 315:987-88.

Bacharier L, Guilbert T, Mauger D, Boehmer S, Beigelman A, Fitzpatrick A, Jackson D, Baxi S, Benson M, Burnham C-A. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children with a History of Such Illnesses a Randomized Clinical Trial. JAMA. 2015; 314:2034-44.

Boat T, Buka S, Perrin J. Children with Mental Disorders Who Receive Disability Benefits a Report from the Iom. JAMA. 2015; 314:2019-20.

Mody RJ, Wu YM, Lonigro RJ, Cao X, Roychowdhury S, Vats P, Frank KM, Prensner JR, Asangani I, Palanisamy N, Dillman JR, Rabah RM, Kunju LP, Everett J, Raymond VM, Ning Y, Su F, Wang R, Stoffel EM, Innis JW, et al. Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth. JAMA. 2015; 314:913-25.

Redington A, Caldarone C. Remote Ischemic Preconditioning and Postoperative Renal Dysfunction. JAMA. 2015; 314:1519-20.

Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, Laptook AR, Sanchez PJ, Van Meurs KP, Wyckoff M, Das A, Hale EC, Ball MB, Newman NS, Schibler K, Poindexter BB, Kennedy KA, Cotten CM, Watterberg KL, D'Angio CT, et al. Trends in Care Practices, Morbidity, and Mortality of Extremely Preterm Neonates, 1993-2012. JAMA. 2015; 314:1039-51.

Lo B, Zhang KJ, Lu W, Zheng LX, Zhang Q, Kanellopoulou C, Zhang Y, Liu ZD, Fritz JM, Marsh R, Husami A, Kissell D, Nortman S, Chaturvedi V, Haines H, Young LR, Mo J, Filipovich AH, Bleesing JJ, Mustillo P, et al. Patients with Lrba Deficiency Show Ctla4 Loss and Immune Dysregulation Responsive to Abatacept Therapy. Science. 2015; 349:436-40.

Rialdi A, Campisi L, Zhao N, Lagda AC, Pietzsch C, Ho JS, Martinez-Gil L, Fenouil R, Chen X, Edwards M, Metreveli G, Jordan S, Peralta Z, Munoz-Fontela C, Bouvier N, Merad M, Jin J, Weirauch M, Heinz S, Benner C, et al. Topoisomerase 1 Inhibition Suppresses Inflammatory Genes and Protects from Death by Inflammation. Science. 2016; 352:aad7993.

Whitsett JA, Morrisey EE. Inflammation. Modulating Pulmonary Inflammation. Science. 2016; 351:662-3.

Abrams AJ, Hufnagel RB, Rebelo A, Zanna C, Patel N, Gonzalez MA, Campeanu IJ, Griffin LB, Groenewald S, Strickland AV, Tao F, Speziani F, Abreu L, Schule R, Caporali L, La Morgia C, Maresca A, Liguori R, Lodi R, Ahmed ZM, et al. Mutations in Slc25a46, Encoding a Ugo1-Like Protein, Cause an Optic Atrophy Spectrum Disorder. Nat Genet. 2015; 47:926-32.

Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, Abedian S, Cheon JH, Cho J, Daryani NE, Franke L, Fuyuno Y, Hart A, Juyal RC, Juyal G, Kim WH, et al. Association Analyses Identify 38 Susceptibility Loci for Inflammatory Bowel Disease and Highlight Shared Genetic Risk across Populations. Nat Genet. 2015; 47:979-86.

Sun C, Molineros JE, Looger LL, Zhou XJ, Kim K, Okada Y, Ma J, Qi YY, Kim-Howard X, Motghare P, Bhattarai K, Adler A, Bang SY, Lee HS, Kim TH, Kang YM, Suh CH, Chung WT, Park YB, Choe JY, et al. High-Density Genotyping of Immune-Related Loci Identifies New Sle Risk Variants in Individuals with Asian Ancestry. Nat Genet. 2016; 48:323-30.

Geiger H. Depleting Senescent Cells to Combat Aging. Nat Med. 2016; 22:23-4.

Li YR, Li J, Zhao SD, Bradfield JP, Mentch FD, Maggadottir SM, Hou C, Abrams DJ, Chang D, Gao F, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Glessner JT, Li D, Kao C, Thomas KA, Qiu H, et al. Meta-Analysis of Shared Genetic Architecture across Ten Pediatric Autoimmune Diseases. Nat Med. 2015; 21:1018-27.

Impact Factor