Lin Fei, PhD

Professor, UC Department of Pediatrics

lin.fei@cchmc.org

About

Biography

As a professor and researcher, I design clinical and non-clinical studies, perform data analysis and presentation and examine mathematical modeling. My primary interests are probability and statistical theory applied to medical research, including distributional theory and optimization.

My interest in this field stems from my mathematical and statistical training and quantitative research. One of my notable discoveries is the probabilistic relationship between sample size and discovery rate in clinical studies, which can be reviewed in some of my publications.

I have been a researcher for over 29 years and began working with Cincinnati Children’s in 2012.

Interests

Statistics; ranking and selection; sequential testing; multiple comparisons; probability modeling; stochastic process inference

Research Areas

Biostatistics and Epidemiology

Publications

Diagnostic accuracy of serum matrix metalloproteinase-7 as a biomarker of biliary atresia in a large North American cohort. Pandurangi, S; Mourya, R; Nalluri, S; Fei, L; Dong, S; Harpavat, S; Guthery, SL; Molleston, JP; Rosenthal, P; Sokol, RJ; Shneider, BL; Horslen, SP; Teckman, JH; Bezerra, JA. Hepatology. 2024; 80:152-162.

High prevalence of gastrointestinal disorders in a large cohort of patients with joint hypermobility. Sood, V; Kaul, A; El-Chammas, KI; Mukkada, VA; Sun, Q; Fei, L; Santucci, NR. Journal of Pediatric Gastroenterology and Nutrition. 2024; 79:42-47.

Exploring Diagnostic Priorities: The Role of Colonic Manometry in Evaluating Pediatric Patients with Intractable Idiopathic Constipation Prior to Sacral Nerve Stimulation. Dorfman, L; El-Chammas, K; Singh, A; Fei, L; Mansi, S; Santucci, NR; Kaul, A. Children. 2024; 11.

Cystatin C Outperforms Creatinine in Predicting Cefepime Clearance in Pediatric Stem Cell Transplant Recipients. Hambrick, HR; Fei, L; Pavia, K; Kaplan, J; Mizuno, T; Tang, P; Schuler, E; Benoit, S; Girdwood, ST. Transplantation and Cellular Therapy. 2024; 30:614.e1-614.e11.

Tu2051 INSIGHTS INTO THE EXPLANTED PANCREAS AND ISLET YIELD: THE ROLE OF IMAGING MARKERS IN PEDIATRIC TOTAL PANCREATECTOMY ISLET AUTOTRANSPLANTATION. Saad, M; Ata, NA; Ahmad, S; Anton, C; Appakalai, BN; Brunner, J; Fei, L; Sun, Q; Abu-El-Haija, M; Trout, AT. Gastroenterology. 2024; 166:s-1507-s-1508.

Diagnostic yield of left-sided colonic manometry in identifying colonic dysmotility in pediatric patients. Dorfman, L; El-Chammas, K; Brijawi, O; Fei, L; Mansi, S; Kaul, A. Neurogastroenterology and Motility. 2024; 36:e14759.

Tu2045 THE CLINICAL SIGNIFICANCE OF ABNORMAL BOLUS CLEARANCE IN PEDIATRIC PATIENTS WITH NORMAL ESOPHAGEAL MANOMETRY METRICS. Elamrati, R; Dorfman, L; Mansi, SM; Fei, L; Kaul, A; El-Chammas, K. Gastroenterology. 2024; 166:s-1505-s-1506.

Su2044 EVALUATING THE UTILITY OF RECORDING FASTING PHASE IN COLONIC MANOMETRY FOR PEDIATRIC PATIENTS. Dorfman, L; Khanna, S; El-Chammas, K; Santucci, NR; Fei, L; Kaul, A. Gastroenterology. 2024; 166:s-904.

Characterization of pharyngeal contractile integral using pharyngeal manometry in children. Damrongmanee, A; El-Chammas, K; Santucci, N; Fei, L; Kaul, A. Journal of Pediatric Gastroenterology and Nutrition. 2024; 78:783-789.

Safety and Effectiveness of Prucalopride in Children with Functional Constipation with and without Upper Symptoms. Velez, A; Kaul, A; El-Chammas, KI; Knowlton, L; Madis, E; Sahay, R; Fei, L; Stiehl, S; Santucci, NR. Pediatric Drugs. 2024; 26:187-195.

Our Response to the IV Fluid Shortage