Lin Fei, PhD

Professor, UC Department of Pediatrics

lin.fei@cchmc.org

About

Biography

As a professor and researcher, I design clinical and non-clinical studies, perform data analysis and presentation and examine mathematical modeling. My primary interests are probability and statistical theory applied to medical research, including distributional theory and optimization.

My interest in this field stems from my mathematical and statistical training and quantitative research. One of my notable discoveries is the probabilistic relationship between sample size and discovery rate in clinical studies, which can be reviewed in some of my publications.

I have been a researcher for over 29 years and began working with Cincinnati Children’s in 2012.

Interests

Statistics; ranking and selection; sequential testing; multiple comparisons; probability modeling; stochastic process inference

Research Areas

Biostatistics and Epidemiology

Publications

Cystatin C Outperforms Creatinine in Predicting Cefepime Clearance in Pediatric Stem Cell Transplant Recipients. Hambrick, HR; Fei, L; Pavia, K; Kaplan, J; Mizuno, T; Tang, P; Schuler, E; Benoit, S; Girdwood, ST. Transplantation and cellular therapy. 2024; 30:614.e1-614.e11.

Tu2051 INSIGHTS INTO THE EXPLANTED PANCREAS AND ISLET YIELD: THE ROLE OF IMAGING MARKERS IN PEDIATRIC TOTAL PANCREATECTOMY ISLET AUTOTRANSPLANTATION. Saad, M; Ata, NA; Ahmad, S; Anton, C; Appakalai, BN; Brunner, J; Fei, L; Sun, Q; Abu-El-Haija, M; Trout, AT. Gastroenterology. 2024; 166:s-1507-s-1508.

Tu2045 THE CLINICAL SIGNIFICANCE OF ABNORMAL BOLUS CLEARANCE IN PEDIATRIC PATIENTS WITH NORMAL ESOPHAGEAL MANOMETRY METRICS. Elamrati, R; Dorfman, L; Mansi, SM; Fei, L; Kaul, A; El-Chammas, K. Gastroenterology. 2024; 166:s-1505-s-1506.

Su2044 EVALUATING THE UTILITY OF RECORDING FASTING PHASE IN COLONIC MANOMETRY FOR PEDIATRIC PATIENTS. Dorfman, L; Khanna, S; El-Chammas, K; Santucci, NR; Fei, L; Kaul, A. Gastroenterology. 2024; 166:s-904.

Safety and Effectiveness of Prucalopride in Children with Functional Constipation with and without Upper Symptoms. Velez, A; Kaul, A; El-Chammas, KI; Knowlton, L; Madis, E; Sahay, R; Fei, L; Stiehl, S; Santucci, NR. Pediatric Drugs. 2024; 26:187-195.

Percutaneous Electrical Nerve Field Stimulation in Children and Adolescents With Functional Dyspepsia-Integrating a Behavioral Intervention. Santucci, NR; Beigarten, AJ; Khalid, F; El-Chammas, KI; Graham, K; Sahay, R; Fei, L; Rich, K; Mellon, M. Neuromodulation. 2024; 27:372-381.

Psychological distress and coping efficacy in children with disorders of gut-brain interaction. Santucci, NR; Velasco-Benitez, CA; Cunningham, N; Li, J; Fei, L; Sun, Q; Saps, M. Neurogastroenterology and Motility. 2024; 36:e14724.

Predictive Value of Laryngeal Penetration to Aspiration in a Cohort of Pediatric Patients. Miller, AL; Miller, CK; Fei, L; Sun, Q; Willging, JP; de Alarcon, A; Pentiuk, SP. Dysphagia. 2024; 39:33-42.

Food Insecurity and Pediatric Nonalcoholic Fatty Liver Disease Severity. Orkin, S; Zhao, X; Setchell, KD R; Carr, E; Arce-Clachar, AC; Bramlage, K; Huang, R; Fei, L; Beck, AF; Fawaz, R; Valentino, PL; Xanthakos, SA; Mouzaki, M. The Journal of Pediatrics. 2024; 265:113818.

Real-Time Acute Kidney Injury Risk Stratification-Biomarker Directed Fluid Management Improves Outcomes in Critically Ill Children and Young Adults. Goldstein, SL; Krallman, KA; Roy, JP; Collins, M; Chima, RS; Basu, RK; Chawla, L; Fei, L. Kidney International Reports. 2023; 8:2690-2700.