Clinical Trials / Research Studies
Autism Spectrum Disorder (ASD) and Depression Study for Teens and Young Adults 13 to 26 years old
Why are we doing this research?
Cincinnati Children's is conducting a research study to evaluate the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) in reducing treatment resistant depressive symptoms in people with autism spectrum disorder (ASD). We want to better understand how to treat depression for those diagnosed with ASD.
Who can participate?
Teens and young adults 13 to 26 years old who:
- Have been diagnosed on the autism spectrum
- Have major depressive disorder (MDD)
- Have tried and not received benefit from at least one evidence-based antidepressant treatment
Conditions
- Autism
- Disabilities: Intellectual
- Mental Health
What will happen in the study?
This study includes 10 study visits at Cincinnati Children’s over 14 weeks. Here are some of the things that will happen in this study.
You or your child will be asked to:
- Go through the consent process with a research coordinator.
- Fill out questionnaires.
- Have sessions of TBS.
- Have neuropsychological testing: You will be given several tests of your memory, concentration, and motor skills.
- Submit a urine-based pregnancy test and drug screening.
- Be given an EEG. Have psychological assessments
What are the good things that can happen from this research?
You, or your child as the participant, will be receiving a treatment that is FDA approved to treat depression in adults and adolescents, and it is likely you may receive a benefit from this therapy. However, there is no guarantee that you will benefit from participating in this study.
What are the bad things that can happen from this research?
Possible risks and discomforts will be discussed with adult participants, parents or guardians interested in learning more about the study.
Will you/your child be paid to be in this research study?
Participants will receive up to $650 for participation in this study.
Contact
Priya Rameshpriya.ramesh@cchmc.org
513-636-4433
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave.
Cincinnati, OH 45229-3039
Study Doctor
Rana Elmaghraby, MD
Psychiatry
Cincinnati Children’s Hospital Medical Center
3333 Burnet Avenue, Cincinnati, Ohio 45229-3026
© 1999-2024 Cincinnati Children's Hospital Medical Center. All rights reserved.
