The researchers are doing this study to see if early reinfusion of tisagenlecleucel can keep participants in B-CEll ApLasia at 6 months after their first infusion. The researchers will also look at the safety of early reinfusion and how effective it is at treating B-ALL.
22-220 REFUEL: Phase II Open Label Multicenter Study of Early REinFusion of Tisagenlecleucel to Promote DUrable B-CEll ApLasia in Pediatric and Young Adult Patients With Relapsed/Refractory CD19-Positive B-Cell Acute Lymphoblastic Leukemia (REFUEL).
Inclusion Criteria:
Age Mean GFR +/-SD (mL/min/1.73 m2)
Exclusion Criteria:
Age Mean GFR +/-SD (mL/min/1.73 m2)