Measurement Method
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Strengths
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Weaknesses
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Self-Report Questionnaires/ Structured Interviews
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- Easy to complete
- Inexpensive
- Comprehensive & flexible
- Available for multiple informants
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- Overestimates due to reporting biases (“faking good”)
- Recall problems
- Global estimates of behavior
- Not useful for younger children
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Electronic Monitors
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- Precise record of date, time and duration
- Continuous, long-term measurement
- Identification of patterns of non-adherence
- Feedback to patients and families on rates adherence
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- Technical problems
- Expense
- Assumes medication was ingested
- Patient reactivity
- Not available for all treatments (e.g., food intake)
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Pharmacy Refill History
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- Specifies type and amount of medication that was filled
- No patient burden
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- Does not indicate that medication was taken
- Limited to medication regimens
- Can require collecting data from multiple pharmacies
- Difficult to obtain given HIPAA Guidelines
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Biological Assays
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- Objectively verifies drug ingestion
- No reporting biases or recall problems
- Quantifiable
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- Instability of blood levels due to metabolism, food intake, etc.
- Pharmacokinetic variations
- Invasive
- Expensive
- Not useful for all chronic conditions
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Smart Phone Apps
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- Aids the users in tracking adherence
- Can generate alerts to remind users to take or record taking medication
- Can be a motivation aid
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- Limited effectiveness
- Depended on the patient owning a smartphone or tablet
- Not available for all treatments
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End of Module 3
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