Jean Tkach, PhD
- Medical Physicist, Department of Radiology and Medical Imaging
- Professor, UC Department of Radiology
About
Biography
Jean Tkach, PhD, received her undergraduate and graduate training in biomedical engineering. She is an MRI physicist by training who has been involved in MRI research since 1985.
Dr. Tkach joined the Cincinnati Children's faculty in the Fall of 2010. Throughout her career, the majority of her effort has been dedicated to the development, implementation, optimization and application of novel MRI acquisition techniques to address clinical as well as more fundamental research questions. The majority of these efforts have been dedicated toward neuroimaging. However, she has also been actively involved in research to advance the fields of cardiac, body and musculoskeletal MR imaging. Although most of Dr. Tkach's work has been directed toward human imaging, she also has been actively involved in multiple animal MR imaging studies.
Dr. Tkach’s research currently focuses on the development and implementation of state of the art MRI acquisition techniques optimized for (and to best address the most relevant clinical needs of) the neonate that exploit new technology being developed for this purpose. Most recently, Dr. Tkach received the Caffey Award for the Best Basic Science Research Paper at the 2011 Annual Meeting of the International Society for Pediatric Radiology.
Dr. Tkach is also is a consultant on the Circulatory System Devices Panel of the Medical Devices Advisory Committee, Center for Devices and Radiological Health, Food and Drug Administration (FDA).
BSE: Biomedical Engineering, Duke University, 1982.
MS: Biomedical Engineering, Case Western Reserve University, 1985.
PhD: Biomedical Engineering, Case Western Reserve University, 1988.
Interests
Neonatal MR acquisition technique development, optimization and application
Research Areas
Imaging, Fibrosis
Publications
Accelerated Cine Cardiac MRI Using Deep Learning-Based Reconstruction: A Systematic Evaluation. Journal of Magnetic Resonance Imaging. 2024; 60:640-650.
Evaluation of T2W FLAIR MR image quality using artificial intelligence image reconstruction techniques in the pediatric brain. Pediatric Radiology: roentgenology, nuclear medicine, ultrasonics, CT, MRI. 2024; 54:1337-1343.
Precision and Test-Retest Repeatability of Stiffness Measurement with MR Elastography: A Multicenter Phantom Study. Radiology. 2024; 311:e233136.
Implementation of a Program for Appendicitis MRI in a Pediatric Hospital. American Journal of Roentgenology. 2024; 222:e2330695.
Structural connectivity at term equivalent age and language in preterm children at 2 years corrected. Brain Communications. 2024; 6:fcae126.
Corpus Callosum Abnormalities at Term-Equivalent Age Are Associated with Language Development at 2 Years' Corrected Age in Infants Born Very Preterm. 2024; 11:200101.
Technical and Diagnostic Performance of Rapid MRI for Evaluation of Appendicitis in a Pediatric Emergency Department. Academic Radiology. 2024; 31:1102-1110.
MRI AND BLOOD-BASED BIOMARKERS ASSOCIATED WITH SURGICAL MANAGEMENT IN CHILDREN AND ADULTS WITH SMALL BOWEL CROHN'S DISEASE. Gastroenterology. 2024; 166:s19-s20.
MRI AND BLOOD-BASED BIOMARKERS ASSOCIATED WITH SURGICAL MANAGEMENT IN CHILDREN AND ADULTS WITH SMALL BOWEL CROHN'S DISEASE. Inflammatory Bowel Diseases. 2024; 30:s14-s15.
P067 Volumetric Assessment of Treatment Response in Newly Diagnosed Crohn Disease: A Pilot Study. Journal of Crohn's and Colitis. 2024; 18:i337.
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