Dr. Sisk specializes in medical and surgical vitreoretinal diseases including diabetic retinopathy, macular pucker, macular hole, macular degeneration, complicated retinal detachment, retinopathy of prematurity, vascular diseases of the retina, uveitis, histoplasmosis, complications of anterior segment surgery, and ocular trauma. He has special interests in pediatric retinal and surgical diseases, hereditary diseases of the retina, and retinal electrophysiology.

Dr. Sisk is a board certified diplomate of the American Board of Ophthalmology and a fellow of the American College of Surgeons. His peers selected him as one of The Best Doctors in America. He is a member of the Retina Society, the Association of Pediatric Retinal Surgeons, the American Society of Retinal Specialists, the American Academy of Ophthalmology, the Association for Research in Vision and Ophthalmology, and a board member of the Cincinnati Society of Ophthalmology.