With my colleagues, I aim to decipher mechanisms of disease using a variety of microscopy techniques. I try to determine what abnormalities are present, as well as when and where. I am particularly interested in cancer biology, inflammatory response and musculoskeletal aberrations.
My path to research was paved by a curiosity about mysterious, small-scale failures that lead to abnormal functioning in tissues. I love using a microscope, and I have always wanted to help the sick.
A challenge in many tissue studies is identifying which cells make which product. As a pediatric pathologist, I am pleased to contribute to several such co-localization studies involving lesions caused by immunological and cancerous cell changes.
I have won many awards for molecular pathology teaching, including multiple Gold Apple teaching awards from medical students, and multiple Clinical Pathology Teacher of the Year awards from residents. I have also received the Dean’s Award for Teaching Excellence from the College of Medicine.
BSc: University of British Columbia, Vancouver, British Columbia, Canada.
MSc: University of Toronto, Toronto, Ontario, Canada.
MD: University of Calgary, Calgary, Alberta, Canada, 1995.
DABP: Anatomic and Pediatric Pathology.
Microscopic techniques for assessing mRNA expression; protein production and cellular identity in eukaryotic tissues; stem cell development and differentiation using animal models such as the zebrafish
Pathology
Pathology
Identification of alternative protein targets of glutamate-ureido-lysine associated with PSMA tracer uptake in prostate cancer cells. Proceedings of the National Academy of Sciences of USA. 2022; 119.
Integration of Genomic Medicine in Pathology Resident Training. American Journal of Clinical Pathology. 2020; 154:784-791.
Cyclin-like proteins tip regenerative balance in the liver to favour cancer formation. Carcinogenesis. 2020; 41:850-862.
Differential Expression of Glucose Transporters and Hexokinases in Prostate Cancer with a Neuroendocrine Gene Signature: A Mechanistic Perspective for 18F-FDG Imaging of PSMA-Suppressed Tumors. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2020; 61:904-910.
Juvenile OLFM4-null mice are protected from sepsis. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2020; 318:F809-F816.
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