A photo of Natasha Pillay-Smiley.

Natasha Pillay Smiley, DO


  • Pediatric Neuro-Oncologist, Cancer and Blood Diseases Institute
  • Associate Professor, UC Department of Pediatrics

About

Biography

Dr. Pillay Smiley completed her medical training at Chicago College of Osteopathic Medicine and Pediatrics Residency at Advocate Children's Lutheran General Hospital in the Chicago area. She went on to the Pediatric Hematology/Oncology/Stem Cell Transplant Fellowship at Nationwide Children's Hospital in Columbus, OH before returning to Chicago for a Pediatric Neuro-Oncology Fellowship and the start of her career at Northwestern University/Ann & Robert H. Lurie Children's Hospital.

Interests

Pediatric CNS disease; CNS specific survivorship; CNS specific cancer predisposition including NF-1 and NF-2

Services and Specialties

Brain Tumor, Cancer and Blood Diseases

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Publications

14q22.3 duplication including OTX2 in a girl with medulloblastoma: A case report with literature review. Blake, C; Widmeyer, K; DAquila, K; Mochizuki, A; Smolarek, TA; Pillay-Smiley, N; Kim, SY. American Journal of Medical Genetics, Part A. 2024; 194:e63604.

DIPG-91. CLINICAL, RADIOGRAPHIC, HISTOPATHOLOGIC, AND MOLECULAR CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA-AN UPDATE FROM THE INTERNATIONAL AND EUROPEAN SOCIETY FOR PEDIATRIC ONCOLOGY DIPG REGISTRIES (IDIPGR/SIOPE-DIPGR). Pillay-Smiley, N; Nussbaumer, G; Damen-Corbijn, C; Baugh, J; Webster, A; Lane, A; Godschalk, TC; Grill, J; Hawkins, C; Leach, J; Hummel, T; Kramm, C; van Zanten, SV; Hoffman, LM. Neuro-Oncology. 2024; 26:0.

DIPG-67. RE-IRRADIATION PRACTICES AND OUTCOMES IN PATIENTS WITH DIPG/DMG: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY. Pillay-Smiley, N; Webster, A; Lane, A; Hawkins, C; Hassall, T; Leach, J; Jones, B; Dorris, K; Hansford, JR; Zaghloul, M; Cheng, S; Hummel, TR; Hoffman, LM; Warren, KE. Neuro-Oncology. 2024; 26:0.

QOL-38. PSYCHOSOCIAL OUTCOMES OF CHILDREN WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND HIGH-GRADE GLIOMA (HGG) –PROSPECTIVE, LONGITUDINAL PROMIS ASSESSMENTS OF PATIENTS ENROLLED ON CONNECT PHASE I CLINICAL TRIALS. Wright-Nadkarni, ML; Moscato, EL; Stanek, JR; Schaefer, MR; Gerhardt, CA; Ashley, DM; Baxter, PA; Chi, SN; Dorris, K; Fisher, MJ; Murala, M; Mikael, L; Fouladi, M; Lazow, MA. Neuro-Oncology. 2024; 26:0.

LGG-37. A PHASE III STUDY COMPARING TWO CARBOPLATIN CONTAINING REGIMENS FOR CHILDREN AND YOUNG ADULTS WITH PREVIOUSLY UNTREATED LOW-GRADE GLIOMA. Lenen, A; Waanders, AJ; Bazzi, L; Zhang, H; Lai, J; Plant-Fox, AS; Cluster, A; Crawford, J; Cohen, K; Dickens, D; Fangusaro, J; Lulla, R; Goldman, S; Pillay-Smiley, N. Neuro-Oncology. 2024; 26:0.

MDB-09. WNT AND GROUP 4 MEDULLOBLASTOMAS OF EARLY CHILDHOOD TREATED WITH HIGH DOSE CHEMOTHERAPY AND CRANIOSPINAL IRRADIATION SPARING APPROACH. Cansanay, RD; Erker, C; Ratterman, E; Schlosser, MP; Ronsley, R; Cacciotti, C; Hukin, J; Cheng, S; Pillay-Smiley, N; Magimairajan, V; Rutkowski, S; Lassaletta, A; Bouffet, E; Lafay-Cousin, L. Neuro-Oncology. 2024; 26:0.

IMMU-17. A PHASE I STUDY OF INTRATUMORAL/PERITUMORAL HERPES SIMPLEX VIRUS-1 MUTANT HSV1716 IN PATIENTS WITH REFRACTORY OF RECURRENT HIGH-GRADE GLIOMAS: A PEDIATRIC BRAIN TUMOR CONSORTIUM STUDY. Mochizuki, AY; Hummel, TR; Cripe, T; Fouladi, M; Stevenson, CB; Pollack, I; Mitchell, D; Poussaint, TY; Onar-Thomas, A; DeWire-Schottmiller, M; Pillay-Smiley, N. Neuro-Oncology. 2024; 26:0.

DIPG-17. DYSREGULATED PURINE METABOLISM IN A LETHAL CHILDHOOD BRAINSTEM TUMOR REVEALS NEW TREATMENT STRATEGIES WITH OLD DRUGS. Mersich, I; Congrove, S; Horchar, M; Caceres, R; Desai, J; Desai, P; Sallans, L; Haines, J; Menon, R; Stevenson, C; Tavassoli, A; D’Alessandro, A; Phoenix, T; Dasgupta, B. Neuro-Oncology. 2024; 26:0.

QOL-06. RECURRENCE PATTERNS AND SURVEILLANCE IMAGING IN PEDIATRIC BRAIN TUMOR SURVIVORS. Cacciotti, C; Lenzen, A; Self, C; Pillay-Smiley, N. Neuro-Oncology. 2024; 26:0.

LGG-05. REPORT ON PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC)-029B, A PROSPECTIVE PHASE 2 CLINICAL TRIAL OF SELUMETINIB IN TREATING YOUNG PATIENTS WITH RECURRENT/PROGRESSIVE LOW-GRADE GLIOMA: NEW RESULTS ON STRATA 2, 5, AND 6 WITH UPDATED LONG-TERM SURVIVAL OUTCOMES ON STRATA 1, 3, AND 4. Fangusaro, J; Onar-Thomas, A; Poussaint, TY; Lensing, S; Ligon, AH; Lindeman, N; Banerjee, A; Kilburn, L; Lenzen, A; Pillay-Smiley, N; Jones, DT W; Stewart, CF; Fouladi, M; Dunkel, IJ. Neuro-Oncology. 2024; 26:0.

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