I’m an epidemiologist with applied research interests in pediatric cardiology, nutrition, and the impact of the developing infant intestinal microbiome on growth and early development. My areas of methodical research interest include applying and developing analytical methods for microbial metagenomic next-generation sequence data, dietary assessment and analysis methodology, predictive modeling and causal inference.
My interest in research stems from a desire to improve the health outcomes of children. I strive for the thoughtful application of epidemiologic research methods and biostatistics to support evidence-based care.
I collaborate broadly as a quantitative methodologist in health sciences research and lead the Biostatistics, Epidemiology and Research Design (BERD) Core of the Center for Clinical & Translational Science & Training (CCTST), the Microbial Metagenomics Analysis Center, and the Biostatistics Service for the Heart Institute Research Core at Cincinnati Children’s. My current work is largely focused on supporting these core services.
I have been a researcher for over 15 years and began working at Cincinnati Children’s in 2014.
PhD: Columbia University, New York, 2009.
MPhil: Columbia University, New York, 2009.
MS: University of Cincinnati, Cincinnati, OH, 2008.
BS: Miami University, Oxford, OH, 2004.
Pediatric cardiology; microbial metagenomics
Application and development of analytical methods for microbial metagenomic next-generation sequence data; dietary assessment and analysis methodology; predictive modeling; causal inference
Biostatistics and Epidemiology
Patent Ductus Arteriosus and Lung Magnetic Resonance Imaging Phenotype in Moderate and Severe Bronchopulmonary Dysplasia-Pulmonary Hypertension. American Journal of Respiratory and Critical Care Medicine. 2024; 210:318-328.
Crohn's Disease-Associated Pathogenic Mutation in the Manganese Transporter ZIP8 Shifts the Ileal and Rectal Mucosal Microbiota Implicating Aberrant Bile Acid Metabolism. Inflammatory Bowel Diseases. 2024; 30:1379-1388.
Precision in Norwood Shunt Sizing: Single Ventricle Reconstruction Trial Public Dataset Analysis. The Annals of Thoracic Surgery. 2024; 118:459-467.
Associations of Maternal Dietary Inflammation Potential and Body Mass Index with C-Reactive Protein Levels in Human Milk. Current Developments in Nutrition. 2024; 8:102999.
Factors associated with successful liberation from continuous renal replacement therapy in children and young adults: analysis of the worldwide exploration of renal replacement outcomes collaborative in Kidney Disease Registry. Intensive Care Medicine. 2024; 50:861-872.
Clinical Risk Assessment and Prediction in Congenital Heart Disease Across the Lifespan: JACC Scientific Statement. Journal of the American College of Cardiology. 2024; 83:2092-2111.
Cardiac atrial pathology in Duchenne muscular dystrophy. Muscle and Nerve. 2024; 69:572-579.
Mo1794 CROHN'S DISEASE-ASSOCIATED PATHOGENIC MUTATION IN MANGANESE TRANSPORTER ZIP8 SHIFTS THE ILEAL AND RECTAL MUCOSAL MICROBIOTA IMPLICATING ABERRANT BILE ACID METABOLISM. Gastroenterology. 2024; 166:s-1114.
Lung Transplantation for Children with Refractory Acute Respiratory Distress Syndrome. Annals of the American Thoracic Society. 2024; 21:672-675.
Selective Cytopheretic Device Use in Continuous Kidney Replacement Therapy in Children: A Cohort Study With a Historical Comparator. Kidney Medicine. 2024; 6:100792.