Dr. Elif Erkan received the prestigious SPR Fellow's Basic Research Award upon completion of her pediatric nephrology fellowship. She pursued a career as a physician scientist and continued to investigate the mechanism of proteinuria induced injury in proximal tubule cells following her fellowship. Her laboratory demonstrated an important link between endocytic adapter protein disabled-2 (Dab2) that binds to the cytoplasmic tail of albumin receptor megalin and protein kinase B (Akt). She received an NIH career development-KO8 award to support her studies elucidating the link between albumin endocytosis and cell signaling events.
MD: Ankara University School of Medicine, Ankara, Turkey, 1990.
Residency: Pediatrics, Marmara University Hospital, Istanbul, Turkey, 1992-1997.
Residency: Pediatrics, Montefiore Medical Center, Albert Einstein School of Medicine, Bronx, NY, 2000-2002.
Fellowship: Pediatric Nephrology, Montefiore Medical Center, Albert Einstein School of Medicine, Bronx, NY, 1997-2000.
MS: Clinical Research Methods Montefiore Medical Center, Albert Einstein School of Medicine, Bronx, NY, 1998-2001.
Proteinuria; nephrotic syndrome.
Nephrology and Hypertension
Proteinuria induced tubular injury; tubular apoptosis; albumin endocytosis.
Nephrology and Hypertension
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Pregnancy associated TMA in 13-year-old patient successfully treated with Eculizumab: case report. BMC Nephrology. 2022; 23:147.
Hypervitaminosis A in Pediatric Patients With Advanced Chronic Kidney Disease. Journal of Renal Nutrition. 2022; 32:275-281.
Improving Clinical Trials for Anticomplement Therapies in Complement-Mediated Glomerulopathies: Report of a Scientific Workshop Sponsored by the National Kidney Foundation. American Journal of Kidney Diseases. 2022; 79:570-581.
Omentectomy reduces the need for peritoneal dialysis catheter revision in children: a study from the Pediatric Nephrology Research Consortium. Pediatric Nephrology. 2021; 36:3953-3959.
Acute Kidney Injury. Pediatric Critical Care. : Springer Nature; Springer Nature; 2021.
Disarranged Sphingolipid Metabolism From Sphingosine-1-Phosphate Lyase Deficiency Leads to Congenital Nephrotic Syndrome. Kidney International Reports. 2019; 4:1763-1769.
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