A photo of Judith W. Dexheimer.

Judith W. Dexheimer, PhD


  • Associate Professor, UC Department of Pediatrics

About

Biography

The ultimate goal of my research is to harness technology to improve healthcare delivery and the quality of care for children. My research interests include machine learning (ML), decision support, personal health records and multi-center informatics implementations. During my National Library of Medicine (NLM) informatics training, I studied artificial intelligence and implemented reminder systems directly into clinical care in the adult and pediatric emergency departments. My goals are to improve disease detection, especially earlier disease detection, for patients with a long history of illness. I also want to provide technology and healthcare information to underserved populations, improve care delivery and help providers use the computer as a tool that incorporates ML directly into clinical care.

I see myself accomplishing this goal by designing ways to use ML to enhance the patient-clinician experience at the point of care and by improving patient interactions with health technology in and outside of the healthcare encounter.

I was drawn to this field of research after seeing well-designed ML algorithms created but not integrated into clinical care. I also noticed that patients frequently did not have access to their own healthcare data.

Working with a collaborative team, we want to improve the use of informatics. I have experience in designing, implementing and evaluating clinical information systems, including clinical decision support systems, computerized applications for emergency medicine, organizational and workflow aspects of informatics applications.

A few of my accomplishments include:

  • Collaborating with the Pestian lab to develop one of the first real-time integrations of machine learning (epilepsy classifier) into clinical care
  • Working with Dr. Yizhao Ni at Cincinnati Children’s to integrate an automated ML patient screening system into the pediatric emergency department
  • Collaborating with Mary Greiner (Mayerson Center for Safe and Healthy Children) and Sarah Beal (Behavioral Medicine and Clinical Psychology) to develop the IDENTITY platform to share data more efficiently between the hospital and Hamilton county job and family services caseworkers, including automated matching of patients in custody

I was nominated for the Presidential Early Career Awards for Scientists and Engineers (PECASE) in 2017 and invited as a presenter at the Amazon Web Services (AWS) Machine Learning Summit in 2019. I have been a researcher for over nine years and began my work at Cincinnati Children’s in 2011.

MBA: University of Cincinnati, Cincinnati, OH, 2020. 

PhD: Biomedical Informatics, Vanderbilt University, Nashville, TN, 2011.

MS: Biomedical Informatics, Vanderbilt University, Nashville, TN, 2006.

Research Areas

Biomedical Informatics, Emergency Medicine

Publications

Pediatric Health and System Impacts of Mass Incarceration, 2009-2020: A Matched Cohort Study. Boch, S; Wildeman, C; Dexheimer, J; Kahn, R; Lambert, J; Beal, S. Academic Pediatrics. 2024; 24:1285-1295.

3.4 What Matters Most: A Machine Learning Approach to Identify the Most Important Questions in the Automated Risk Assessment of School Violence. Kanbar, L; Osborn, AK; Cifuentes, A; Combs, J; Sorter, MT; Dexheimer, JW; Barzman, DH. Journal of the American Academy of Child and Adolescent Psychiatry. 2024; 63:s206-s207.

Secular and modulator-specific drifts in the predictive performance of a rapid lung function decline algorithm: a cystic fibrosis patient registry study. Wang, Z; Zhou, G; Palipana, A; Gecili, E; Dexheimer, JW; Siracusa, C; Szczesniak, R. 2024; 2:10.

Investigation of bias in the automated assessment of school violence. Kanbar, LJ; Mishra, A; Osborn, A; Cifuentes, A; Combs, J; Sorter, M; Barzman, D; Dexheimer, JW. Journal of Biomedical Informatics. 2024; 157:104709.

Machine Learning-Based Prediction of Escitalopram and Sertraline Side Effects With Pharmacokinetic Data in Children and Adolescents. Poweleit, EA; Vaughn, SE; Desta, Z; Dexheimer, JW; Strawn, JR; Ramsey, LB. Clinical Pharmacology and Therapeutics. 2024; 115:860-870.

Early Identification of Candidates for Epilepsy Surgery: A Multicenter, Machine Learning, Prospective Validation Study. Wissel, BD; Greiner, HM; Glauser, TA; Pestian, JP; Ficker, DM; Cavitt, JL; Estofan, L; Holland-Bouley, KD; Mangano, FT; Szczesniak, RD; Dexheimer, JW. Neurology. 2024; 102:e208048.

Social-environmental phenotypes of rapid cystic fibrosis lung disease progression in adolescents and young adults living in the United States. Palipana, AK; Vancil, A; Gecili, E; Rasnick, E; Ehrlich, D; Pestian, T; Andrinopoulou, ER; Afonso, PM; Keogh, RH; Ni, Y; Dexheimer, JW; Clancy, JP; Ryan, P; Brokamp, C; Szczesniak, RD. Environmental Advances. 2023; 14:100449.

Evaluating the implementation of a dynamic digital application to enable community-based decentralisation of rheumatic heart disease case management in Uganda: protocol for a hybrid type III effectiveness-implementation study. Minja, NW; Pulle, J; Rwebembera, J; De Loizaga, SR; Fall, N; Ollberding, N; Abrams, J; Atala, J; Kamarembo, J; Oyella, L; Danforth, K; Okello, E; Beaton, AZ; Watkins, DA. BMJ Open. 2023; 13:e071540.

Development and User Testing of a Dynamic Tool for Rheumatic Heart Disease Management. De Loizaga, SR; Pulle, J; Rwebembera, J; Abrams, J; Atala, J; Chesnut, E; Danforth, K; Fall, N; Felicelli, N; Lapthorn, K; Zühlke, L; Okello, E; Beaton, A; Dexheimer, JW. Applied Clinical Informatics - ACI. 2023; 14:866-877.

1.2 Forecasting Best Performance with Incomplete Resources: Automated Risk Assessment of School Violence. Kanbar, L; Mishra, A; Osborn, AK; Cifuentes, A; Combs, J; Sorter, MT; Dexheimer, JW; Barzman, DH. Journal of the American Academy of Child and Adolescent Psychiatry. 2023; 62:s155.