My philosophy of care is to be compassionate and honest, even when the news is difficult. This approach is how I hope my own family would be treated.
James F. Cnota, MD

About

Biography

While pediatric cardiology involves aspects of acute care and technical expertise, I chose this specialty because my relationship with patients and families is often long-lasting. A fetal cardiologist starts a relationship at the time of prenatal diagnosis, helps a family through the stress of the diagnosis and early cardiac care, and then watches as the child grows up. This relationship with patients and families is very fulfilling for me.

As a pediatric cardiologist, I treat children with congenital heart defects. I am also involved with echocardiography, and I direct the Fetal Heart Program at Cincinnati Children’s. My philosophy of care is to be compassionate and honest, even when the news is difficult. This approach is how I hope my own family would be treated.

The Fetal Heart Program can make a detailed diagnosis that informs prenatal counseling and care. In partnership with the obstetrician, we support mothers and families in a comprehensive manner to achieve the best possible delivery outcome for mom and cardiac outcome for the baby.

In my research, my colleagues and I are trying to improve outcomes in children with heart disease through multicenter research collaborations. We are also seeking to understand how genetics contributes to the cause of congenital heart disease and how genetics contributes to differences in outcomes between patients with congenital heart disease. Another goal is to understand why babies with congenital heart disease are often born too small and too early.

In my free time, I enjoy relaxing with my family, running and travel.

BS: Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, 1991.

MD: Tulane University School of Medicine, New Orleans, Louisiana, 1995.

Residency: University of Arizona Health Sciences Center, Tucson, Arizona, 1998.

Fellowship: Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2001.

MS: Clinical Epidemiology and Health Services Research, Wake Forest University School of Medicine, Winston-Salem, North Carolina, 2005.

Interests

Congenital heart disease; echocardiography; fetal cardiology; Cardiology Consult Service; General Cardiology Outpatient Clinic; Interstage Program

Services and Specialties

Fetal Care, Single Ventricular Interstage, Cardiac MRI, Heart

Interests

Multicenter clinical studies; perinatal outcomes in congenital heart disease

Research Areas

Cardiology, Heart

Insurance Information

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Publications

Selected

Effect of fetal hemodynamics on growth in fetuses with single ventricle or transposition of the great arteries. Alsaied, T; Tseng, S; King, E; Hahn, E; Divanovic, A; Habli, M; Cnota, J. Ultrasound in Obstetrics and Gynecology. 2018; 52:479-487.

Selected

Preoperative Aortic Arch Size and Late Outcome After Coarctation Repair by Lateral Thoracotomy. Ramachandran, P; Khoury, PR; Beekman, RH; Michelfelder, EC; Manning, PB; Tweddell, JS; Cnota, JF. The Annals of Thoracic Surgery. 2018; 106:575-580.

Selected

Fetal somatic growth trajectory differs by type of congenital heart disease. Puri, K; Warshak, CR; Habli, MA; Yuan, A; Sahay, RD; King, EC; Divanovic, A; Cnota, JF. Pediatric Research. 2018; 83:669-676.

Selected

Relationship of Echocardiographic Z Scores Adjusted for Body Surface Area to Age, Sex, Race, and Ethnicity: The Pediatric Heart Network Normal Echocardiogram Database. Lopez, L; Colan, S; Stylianou, M; Granger, S; Trachtenberg, F; Frommelt, P; Pearson, G; Camarda, J; Cnota, J; Cohen, M; Thankavel, P; van der Velde, M; Minich, L; Investigators, PH N. Circulation: Cardiovascular Imaging. 2017; 10.

Selected

Hypoplastic left heart syndrome is associated with structural and vascular placental abnormalities and leptin dysregulation. Jones, HN; Olbrych, SK; Smith, KL; Cnota, JF; Habli, M; Ramos-Gonzales, O; Owens, KJ; Hinton, AC; Polzin, WJ; Muglia, LJ; Hinton, RB. Placenta. 2015; 36:1078-1086.

Selected

Somatic growth trajectory in the fetus with hypoplastic left heart syndrome. Cnota, JF; Hangge, PT; Wang, Y; Woo, JG; Hinton, AC; Divanovic, AA; Michelfelder, EC; Hinton, RB. Pediatric Research. 2013; 74:284-289.

Selected

Superior cavopulmonary anastomosis timing and outcomes in infants with single ventricle. Cnota, JF; Allen, KR; Colan, S; Covitz, W; Graham, EM; Hehir, DA; Levine, JC; Margossian, R; McCrindle, BW; Minich, LL; Natarajan, S; Richmond, ME; Hsu, DT; Investigat, PH N. Journal of Thoracic and Cardiovascular Surgery. 2013; 145:1288-1296.

Selected

Congenital heart disease infant death rates decrease as gestational age advances from 34 to 40 weeks. Cnota, JF; Gupta, R; Michelfelder, EC; Ittenbach, RF. The Journal of Pediatrics. 2011; 159:761-765.

Selected

Prediction and perinatal management of severely restrictive atrial septum in fetuses with critical left heart obstruction: clinical experience using pulmonary venous Doppler analysis. Divanovic, A; Hor, K; Cnota, J; Hirsch, R; Kinsel-Ziter, M; Michelfelder, E. Journal of Thoracic and Cardiovascular Surgery. 2011; 141:988-994.

Identifying novel data-driven subgroups in congenital heart disease using multi-modal measures of brain structure. Vandewouw, MM; Norris-Brilliant, A; Rahman, A; Assimopoulos, S; Morton, SU; Kushki, A; Cunningham, S; King, E; Goldmuntz, E; Miller, TA; Panigrahy, A; Lerch, JP; Gelb, BD; Anagnostou, E. Neuroimage. 2024; 297:120721.

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