About

MD: UT Southwestern, Dallas, TX, 1993.

Residency: Children's Hospital of Dallas, Dallas, TX, 1996.

Fellowship: The Children's Hospital, Denver, CO, 2002.

Certification: American Board of Pediatrics, 1996; Sub-board of Pediatric Heme/Onc, 2002.

Interests

Histiocytic disorders: HLH and LCH

Services and Specialties

Cancer and Blood Diseases, Immune Deficiencies and Histiocytosis, Bone Marrow Transplantation BMT, Leukemia, Hemophagocytic lymphohistiocytosisHLH, Histiocytosis Center, Autoimmune Liver Disease, Rare Lung Diseases

Interests

Better understanding histiocytic disorders and developing novel therapies for them; regulation of the immune response; immunotherapy of cancer

Research Areas

Bone Marrow Transplantation and Immune Deficiency, Cancer and Blood Diseases, Immunobiology

Insurance Information

Cincinnati Children's strives to accept a wide variety of health plans. Please contact your health insurance carrier to verify coverage for your specific benefit plan.

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Publications

Emapalumab Treatment in Patients With Rheumatologic Disease-Associated Hemophagocytic Lymphohistiocytosis in the United States: A Retrospective Medical Chart Review Study. Chandrakasan, S; Allen, CE; Bhatla, D; Carter, J; Chien, M; Cooper, R; Draper, L; Eckstein, OS; Hanna, R; Hays, JA; Hermiston, ML; Modica, R; Baker, A; Ward, B. Arthritis and Rheumatology. 2025; 77:226-238.

The role of C-reactive protein and ferritin in the diagnosis of HLH, adult-onset still's disease, and COVID-19 cytokine storm. Goubran, M; Spaner, C; Stukas, S; Zoref-Lorenz, A; Shojania, K; Beckett, M; Li, A; Peterson, E; Sekhon, M; Grey, R; Mattman, A; Jordan, MB; Chen, LY C; Setiadi, A. Scientific Reports. 2024; 14:31306.

Emapalumab therapy for hemophagocytic lymphohistiocytosis before reduced-intensity transplantation improves chimerism. Verkamp, B; Jodele, S; Sabulski, A; Marsh, R; Kieser, P; Jordan, MB. Blood. 2024; 144:2625-2636.

Diagnostic guidelines for familial hemophagocytic lymphohistiocytosis revisited. Henter, JI; Sieni, E; Eriksson, J; Bergsten, E; Hed Myrberg, I; Canna, SW; Coniglio, ML; Cron, RQ; Kernan, KF; Kumar, AR; Bottai, M; Bryceson, YT; Horne, AC; Jordan, MB. Blood. 2024; 144:2308-2318.

Insights into the Natural History and Treatment Outcomes of Hemophagocytic Lymphohistiocytosis (INTO-HLH) Patient Registry: Study Design and Clinical Characteristics. Zoref-Lorenz, A; Fajgenbaum, DC; Korn, S; Kaufmann, T; Anderson, B; Oladapo, A; Saltonstall, L; Fournier, D; Behrens, E; Allen, CE; Jordan, MB. Blood. 2024; 144:5389.

Assessment of the Optimized HLH Inflammatory (OHI) Index in a Prospective Cohort of Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma. Zoref-Lorenz, A; Cahn, EJ; Mou, E; Wang, Y; Maurer, MJ; Feldman, AL; Negaard, BJ; Mwangi, R; Itchaki, G; Nowakowski, GS; Goyal, G; Witzig, TE; Cerhan, JR; Jordan, MB. Blood. 2024; 144:1624.

Transplant Related Outcomes in Patients with Hemophagocytic Lymphohistiocytosis Treated with Emapalumab As a Bridge to Hematopoietic Stem Cell Transplantation: The Real-HLH Study. Allen, CE; Chandrakasan, S; Jordan, MB; Leiding, JW; Marrone, M; Oladapo, A; Pednekar, P; Walkovich, KJ; Yee, J. Blood. 2024; 144:3489.

Targeting PRMT5 in Primary Hemophagocytic Lymphohistiocytosis: A Novel Therapeutic Approach Using a Perforin-Deficient Mouse Model. Steyn, S; Chen, C; Saadey, R; Mao, C; Scherle, PA; Bhagwat, N; Vaddi, K; Brooks, E; Baiocchi, R; Jordan, MB; Shindiapina, P. Blood. 2024; 144:809.

Real-world treatment patterns and outcomes in patients with primary hemophagocytic lymphohistiocytosis treated with emapalumab. Chandrakasan, S; Jordan, MB; Baker, A; Behrens, EM; Bhatla, D; Chien, M; Eckstein, OS; Henry, MM; Hermiston, ML; Hinson, AP; Walkovich, KJ; Yee, JD; Zoref-Lorenz, A; Allen, CE. Blood Advances. 2024; 8:2248-2258.

COVID-19 Vaccination in Patients with Inborn Errors of Immunity Reduces Hospitalization and Critical Care Needs Related to COVID-19: a USIDNET Report. McDonnell, J; Cousins, K; Younger, ME M; Lane, A; Abolhassani, H; Abraham, RS; Al-Tamemi, S; Aldave-Becerra, JC; Al-Faris, EH; Alfaro-Murillo, A; Lim, XR; Lopes, JP; López, AL; Tarquini, L. Journal of Clinical Immunology. 2024; 44:86.

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4.6
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