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Sean R. Moore, MD, MS


  • Division Director, Division of Gastroenterology, Hepatology and Nutrition
  • Professor, UC Department of Pediatrics

About

BA: Asbury University, Wilmore, KY, 1996.

MS: University of Virginia, Charlottesville ,1998.

MD: Johns Hopkins University, Baltimore, MD, 2003.

Residency: Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 2006.

Fellowship: Gastroenterology and Nutrition, Vanderbilt University Medical Center, Nashville, TN, 2009.

Certification: Pediatric Gastroenterology.

Interests

Pediatric gastroenterology; enteropathies; undernutrition; global health

Services and Specialties

Gastroenterology

Interests

Structure and function of the gastrointestinal tract in the context of childhood nutrition, growth, immunity, and host-microbe interactions

Research Areas

Gastroenterology Hepatology and Nutrition

Publications

A novel method for culturing enteric neurons generates neurospheres containing functional myenteric neuronal subtypes. Mandal, A; Moneme, C; Tewari, BP; Goldstein, AM; Sontheimer, H; Cheng, L; Moore, SR; Levin, D. Journal of Neuroscience Methods. 2024; 407:110144.

A shared group of bacterial taxa in the duodenal microbiota of undernourished Pakistani children with environmental enteric dysfunction. Iqbal, NT; Chen, RY; Griffin, NW; Hibberd, MC; Khalid, A; Sadiq, K; Jamil, Z; Ahmed, K; Iqbal, J; Hotwani, A; Moore, SR; Ali, A; Barratt, MJ; Gordon, JI. mSphere. 2024; 9:e0019624.

Machine-learning-based integrative -'omics analyses reveal immunologic and metabolic dysregulation in environmental enteric dysfunction. Zulqarnain, F; Zhao, X; Setchell, KD R; Sharma, Y; Fernandes, P; Srivastava, S; Shrivastava, A; Ehsan, L; Jain, V; Raghavan, S; Brown, DE; Moore, SR; Ali, SA; Syed, S. iScience. 2024; 27:110013.

Microbial cues stimulate linear growth in undernourished mice. Moneme, C; Moore, SR. Nature Reviews: Gastroenterology and Hepatology. 2023; 20:485-486.

Impact of diarrhoea and acute respiratory infection on environmental enteric dysfunction and growth of malnourished children in Pakistan: a longitudinal cohort study. Sarfraz, A; Jamil, Z; Ahmed, S; Umrani, F; Qureshi, AK; Jakhro, S; Sajid, M; Rahman, N; Rizvi, A; Ma, JZ; Iqbal, J; Sadiq, K; Moore, SR; Ali, SA. The Lancet Regional Health - Southeast Asia. 2023; 15:100212.

Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease. Braun, T; Sosnovski, KE; Amir, A; BenShoshan, M; VanDussen, KL; Karns, R; Levhar, N; Abbas-Egbariya, H; Hadar, R; Efroni, G; Ferrer, J; Hyams, JS; Denson, LA; Haberman, Y. JCI insight. 2023; 8.

Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan. Sarfraz, A; Ahmed, S; Muhammad, S; Rehman, N; Soomro, SI; Qureshi, K; Jakhro, S; Umrani, F; Greene, A; Syed, S; Moore, SR; Ali, SA. PloS one. 2023; 18:e0287962.

GATA6-AS1 Regulates Intestinal Epithelial Mitochondrial Functions, and its Reduced Expression is Linked to Intestinal Inflammation and Less Favourable Disease Course in Ulcerative Colitis. Sosnovski, KE; Braun, T; Amir, A; Moshel, D; Benshoshan, M; Vandussen, KL; Levhar, N; Abbas-Egbariya, H; Beider, K; Ben-Yishay, R; Ulitsky, I; Hyams, JS; Denson, LA; Haberman, Y. Journal of Crohn's and Colitis. 2023; 17:960-971.

Quantitative Morphometry and Machine Learning Model to Explore Duodenal and Rectal Mucosal Tissue of Children with Environmental Enteric Dysfunction. Khan, M; Jamil, Z; Ehsan, L; Zulqarnain, F; Srivastava, S; Siddiqui, S; Fernandes, P; Raghib, M; Sengupta, S; Mujahid, Z; Moore, S; Ali, SA; Iqbal, J; Syed, S. American Journal of Tropical Medicine and Hygiene. 2023; 108:672-683.

Essential Fatty Acid Deficiency Associates with Growth Faltering and Environmental Enteric Dysfunction in Children. Narvaez-Rivas, M; Setchell, KD R; Galandi, SL; Zhao, X; Iqbal, NT; Ahmed, S; Iqbal, J; Syed, S; Ali, SA; Moore, SR. Metabolites. 2023; 13.